UniProtKB - B7Z425 (B7Z425_HUMAN)
Protein
Submitted name:
Syntaxin 4A (Placental), isoform CRA_a
Gene
STX4A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- SNAP receptor activity Source: InterPro
GO - Biological processi
- intracellular protein transport Source: InterPro
- vesicle-mediated transport Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Syntaxin 4A (Placental), isoform CRA_aImportedSubmitted name: cDNA FLJ57517, highly similar to Syntaxin-4Imported |
Gene namesi | Name:STX4AImported ORF Names:hCG_21149Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 196 – 218 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 122 – 184 | T-SNARE coiled-coil homologyInterPro annotationAdd BLAST | 63 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 5 – 25 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the syntaxin family.ARBA annotation
Keywords - Domaini
Coiled coilPROSITE-ProRule annotationARBA annotation, Transmembrane, Transmembrane helixSequence analysisFamily and domain databases
CDDi | cd00179, SynN, 1 hit |
InterProi | View protein in InterPro IPR010989, SNARE IPR006012, Syntaxin/epimorphin_CS IPR006011, Syntaxin_N IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit PF00804, Syntaxin, 1 hit |
SMARTi | View protein in SMART SM00397, t_SNARE, 1 hit |
SUPFAMi | SSF47661, SSF47661, 1 hit |
PROSITEi | View protein in PROSITE PS00914, SYNTAXIN, 1 hit PS50192, T_SNARE, 1 hit |
i Sequence
Sequence statusi: Complete.
B7Z425-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKQELQNLRD EIKQLGREIR LQLKAIEPQK EEADENYNSV NTRMRKTQHG
60 70 80 90 100
VLSQQFVELI NKCNSMQSEY REKNVERIRR QLKITNAGMV SDEELEQMLD
110 120 130 140 150
SGQSEVFVSN ILKDTQVTRQ ALNEISARHS EIQQLERSIR ELHDIFTFLA
160 170 180 190 200
TEVEMQGEMI NRIEKNILSS ADYVERGQEH VKTALENQKK ARKKKVLIAI
210
CVSITVVLLA VIIGVTVVG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK296652 mRNA Translation: BAH12411.1 CH471192 Genomic DNA Translation: EAW52175.1 |
RefSeqi | NP_001259024.1, NM_001272095.1 |
Genome annotation databases
GeneIDi | 6810 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK296652 mRNA Translation: BAH12411.1 CH471192 Genomic DNA Translation: EAW52175.1 |
RefSeqi | NP_001259024.1, NM_001272095.1 |
3D structure databases
SMRi | B7Z425 |
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | B7Z425 |
PRIDEi | B7Z425 |
Protocols and materials databases
DNASUi | 6810 |
Genome annotation databases
GeneIDi | 6810 |
Organism-specific databases
CTDi | 6810 |
Miscellaneous databases
BioGRID-ORCSi | 6810, 209 hits in 997 CRISPR screens |
ChiTaRSi | STX4, human |
GenomeRNAii | 6810 |
Family and domain databases
CDDi | cd00179, SynN, 1 hit |
InterProi | View protein in InterPro IPR010989, SNARE IPR006012, Syntaxin/epimorphin_CS IPR006011, Syntaxin_N IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit PF00804, Syntaxin, 1 hit |
SMARTi | View protein in SMART SM00397, t_SNARE, 1 hit |
SUPFAMi | SSF47661, SSF47661, 1 hit |
PROSITEi | View protein in PROSITE PS00914, SYNTAXIN, 1 hit PS50192, T_SNARE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B7Z425_HUMAN | |
Accessioni | B7Z425Primary (citable) accession number: B7Z425 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 3, 2009 |
Last sequence update: | March 3, 2009 | |
Last modified: | April 7, 2021 | |
This is version 78 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |