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Protein
Submitted name:

cDNA FLJ50413, highly similar to Tyrosine-protein phosphatase non-receptor type3 (EC 3.1.3.48)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei510Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphataseSAAS annotation, ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ50413, highly similar to Tyrosine-protein phosphatase non-receptor type3 (EC 3.1.3.48)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiB7Z3R0
PRIDEiB7Z3R0

Structurei

3D structure databases

ProteinModelPortaliB7Z3R0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini178 – 250PDZInterPro annotationAdd BLAST73
Domaini314 – 569Tyrosine-protein phosphataseInterPro annotationAdd BLAST256
Domaini487 – 560TYR_PHOSPHATASE_2InterPro annotationAdd BLAST74

Phylogenomic databases

HOVERGENiHBG008322

Family and domain databases

Gene3Di2.30.29.30, 1 hit
3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
IPR011993 PH-like_dom_sf
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR000387 TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00595 PDZ, 1 hit
PF00102 Y_phosphatase, 1 hit
PRINTSiPR00700 PRTYPHPHTASE
SMARTiView protein in SMART
SM00228 PDZ, 1 hit
SM00194 PTPc, 1 hit
SM00404 PTPc_motif, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
SSF52799 SSF52799, 1 hit
PROSITEiView protein in PROSITE
PS50106 PDZ, 1 hit
PS00383 TYR_PHOSPHATASE_1, 1 hit
PS50056 TYR_PHOSPHATASE_2, 1 hit
PS50055 TYR_PHOSPHATASE_PTP, 1 hit

Sequencei

Sequence statusi: Complete.

B7Z3R0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNYRSCKNL WKSCVEHHTF FQAKKLLPQE KNVLSQYWTM GSRNTKKRSP
60 70 80 90 100
RLRHEIRKPR HSSADNLANE MTYITETEDV FYTYKGSLAP QDSDSEVSQN
110 120 130 140 150
RSPHQESLSE NNPAQSYLTQ KSSSSVSPSS NAPGSCSPDG VDQQLLDDFH
160 170 180 190 200
RVTKGGSTED ASQYYCDKND NGDSYLVLIR ITPDEDGKFG FNLKGGVDQK
210 220 230 240 250
MPLVVSRINP ESPADTCIPK LNEGDQIVLI NGRDISEHTH DQVVMFIKAS
260 270 280 290 300
RESHSRELAL VIRRRAVRSF ADFKSEDELN QLFPEAIFPM CPEGGDTLEG
310 320 330 340 350
SMAQLKKGLE SGTVLIQFEQ LYRKKPGLAI TFAKLPQNLD KNRYKDVLPY
360 370 380 390 400
DTTRVLLQGN EDYINASYVN MGIPAANLVN KYIATQGPLP HTCAQFWQVV
410 420 430 440 450
WDQKLSLIVM LTTLTERGRT KCHQYWPDPP DVMNHGGFHI QCQSEDCTIA
460 470 480 490 500
YVSREMLVTN TQTGEEHTVT HLQYVAWPDH GVPDDSSDFL EFVNYVRSLR
510 520 530 540 550
VDSEPVLVHC SAGIGRTGVL VTMETAMCLT ERNLPIYPLD IVRKMRDQRA
560 570 580
MMVQTSSQYK FVCEAILRVY EEGLVQMLDP S
Length:581
Mass (Da):65,816
Last modified:March 3, 2009 - v1
Checksum:i8622A143249D9F25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK296265 mRNA Translation: BAH12296.1
UniGeneiHs.436429

Similar proteinsi

Entry informationi

Entry nameiB7Z3R0_HUMAN
AccessioniPrimary (citable) accession number: B7Z3R0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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