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Protein
Submitted name:

cDNA FLJ55326, highly similar to Ral guanine nucleotide dissociation stimulator

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGuanine-nucleotide releasing factorPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ55326, highly similar to Ral guanine nucleotide dissociation stimulatorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

PTM / Processingi

Proteomic databases

PRIDEiB7Z1W0

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini183 – 320N-terminal Ras-GEFInterPro annotationAdd BLAST138
Domaini457 – 719Ras-GEFInterPro annotationAdd BLAST263
Domaini869 – 956Ras-associatingInterPro annotationAdd BLAST88

Phylogenomic databases

eggNOGiKOG3629 Eukaryota
ENOG410ZUT5 LUCA
HOGENOMiHOG000231592
HOVERGENiHBG005864

Family and domain databases

CDDicd00155 RasGEF, 1 hit
cd06224 REM, 1 hit
Gene3Di1.10.840.10, 1 hit
InterProiView protein in InterPro
IPR000159 RA_dom
IPR015758 RalGDS
IPR000651 Ras-like_Gua-exchang_fac_N
IPR019804 Ras_G-nucl-exch_fac_CS
IPR023578 Ras_GEF_dom_sf
IPR001895 RASGEF_cat_dom
IPR036964 RASGEF_cat_dom_sf
IPR029071 Ubiquitin-like_domsf
PANTHERiPTHR23113:SF35 PTHR23113:SF35, 1 hit
PfamiView protein in Pfam
PF00788 RA, 1 hit
PF00617 RasGEF, 1 hit
PF00618 RasGEF_N, 1 hit
SMARTiView protein in SMART
SM00314 RA, 1 hit
SM00147 RasGEF, 1 hit
SM00229 RasGEFN, 1 hit
SUPFAMiSSF48366 SSF48366, 2 hits
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50200 RA, 1 hit
PS00720 RASGEF, 1 hit
PS50009 RASGEF_CAT, 1 hit
PS50212 RASGEF_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

B7Z1W0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHRRRLALGL GFCLLAGTSL SVLWVYLENW LPVSYVPYYL PCPEILPMMM
60 70 80 90 100
ALSCLCHQQH EAALQEGEAT PARGMVTVPS AQAAGAQAHT AADTHTLVGA
110 120 130 140 150
HRLRGNLQPR ASAAHLPATE PDHWGHGVCR GESSTQEIGE ELINGVIYSI
160 170 180 190 200
SLRKVQLHHG GNKGQRWLGY ENESALNLYE TCKVRTVKAG TLEKLVEHLV
210 220 230 240 250
PAFQGSDLSY VTIFLCTYRA FTTTQQVLDL LFKRYGRCDA LTASSRYGCI
260 270 280 290 300
LPYSDEDGGP QDQLKNAISS ILGTWLDQYS EDFCQPPDFP CLKQLVAYVQ
310 320 330 340 350
LNMPGSDLER RAHLLLAQLE HSEPIEAEPE ALSPVPALKP TPELELALTP
360 370 380 390 400
ARAPSPVPAP APEPEPAPTP APGSELEVAP APAPELQQAP EPAVGLESAP
410 420 430 440 450
APALELEPAP EQDPAPSQTL ELEPAPAPVP SLQPSWPSPV VAENGLSEEK
460 470 480 490 500
PHLLVFPPDL VAEQFTLMDA ELFKKVVPYH CLGSIWSQRD KKGKEHLAPT
510 520 530 540 550
IRATVTQFNS VANCVITTCL GNRSTKAPDR ARVVEHWIEV ARECRILKNF
560 570 580 590 600
SSLYAILSAL QSNSIHRLKK TWEDVSRDSF RIFQKLSEIF SDENNYSLSR
610 620 630 640 650
ELLIKEGTSK FATLEMNPKR AQKRPKETGI IQGTVPYLGT FLTDLVMLDT
660 670 680 690 700
AMKDYLYGRL INFEKRRKEF EVIAQIKLLQ SACNNYSIAP DEQFGAWFRA
710 720 730 740 750
VERLSETESY NLSCELEPPS ESASNTLRTK KNTAIVKRWS DRQAPSTELS
760 770 780 790 800
TSGSSHSKSC DQLRCGPYLS SGDIADALSV HSAGSSSSDV EEINISFVPE
810 820 830 840 850
SPDGQEKKFW ESASQSSPET SGISSASSST SSSSASTTPV AATRTHKRSV
860 870 880 890 900
SGLCNSSSAL PLYNQQVGDC CIIRVSLDVD NGNMYKSILV TSQDKAPAVI
910 920 930 940 950
RKAMDKHSLE EEEPEDYELL QILSDDRKLK IPENANVFYA MNSTANYDFV
960 970 980
LKKRTFTKGV KVKHGASSTL PRMKQKGLKI AKGIF
Length:985
Mass (Da):108,223
Last modified:March 3, 2009 - v1
Checksum:i37263491DFB5A26B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293997 mRNA Translation: BAH11646.1

Similar proteinsi

Entry informationi

Entry nameiB7Z1W0_HUMAN
AccessioniPrimary (citable) accession number: B7Z1W0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 18, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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