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Protein

RNA binding protein fox-1 homolog

Gene

RBFOX1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

RNA-binding protein that regulates alternative splicing events.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingUniRule annotation
Biological processmRNA processing, mRNA splicingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA binding protein fox-1 homologUniRule annotation
Gene namesi
Name:RBFOX1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000078328.19
HGNCiHGNC:18222 RBFOX1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000078328

PTM / Processingi

Proteomic databases

MaxQBiB7Z1U7
PeptideAtlasiB7Z1U7
PRIDEiB7Z1U7

Expressioni

Gene expression databases

BgeeiENSG00000078328
ExpressionAtlasiB7Z1U7 baseline and differential

Interactioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei161Interaction with RNAUniRule annotation1
Sitei169Interaction with RNAUniRule annotation1
Sitei170Interaction with RNAUniRule annotation1
Sitei194Interaction with RNAUniRule annotation1
Sitei199Interaction with RNAUniRule annotation1
Sitei203Interaction with RNAUniRule annotation1
Sitei227Interaction with RNAUniRule annotation1
Sitei237Interaction with RNAUniRule annotation1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini160 – 236RRMInterPro annotationAdd BLAST77

Phylogenomic databases

eggNOGiKOG0125 Eukaryota
ENOG4111WJT LUCA
GeneTreeiENSGT00390000013767
HOVERGENiHBG000044

Family and domain databases

CDDicd12407 RRM_FOX1_like, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR025670 Fox-1_C_dom
IPR034237 FOX1_RRM
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR017325 RNA-bd_Fox-1
IPR000504 RRM_dom
PfamiView protein in Pfam
PF12414 Fox-1_C, 1 hit
PF00076 RRM_1, 1 hit
PIRSFiPIRSF037932 Ataxin_2_bd_A2BP, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequencei

Sequence statusi: Complete.

B7Z1U7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METGQRTHAS GTYSFLDRTQ HSDIKADCNT CVEIEDRKVS RQQMNCEREQ
60 70 80 90 100
LRGNQEAAAA PDTMAQPYAS AQFAPPQNGI PAEYTAPHPH PAPEYTGQTT
110 120 130 140 150
VPEHTLNLYP PAQTHSEQSP ADTSAQTVSG TATQTDDAAP TDGQPQTQPS
160 170 180 190 200
ENTENKSQPK RLHVSNIPFR FRDPDLRQMF GQFGKILDVE IIFNERGSKG
210 220 230 240 250
FGFVTFENSA DADRAREKLH GTVVEGRKIE VNNATARVMT NKKTVNPYTN
260 270 280 290 300
GWKLNPVVGA VYSPEFYAGT VLLCQANQEG SSMYSAPSSL VYTSAMPGFP
310 320 330 340 350
YPAATAAAAY RGAHLRGRGR TVYNTFRAAA PPPPIPAYGG VVYQDGFYGA
360 370 380 390 400
DIYGGYAAYR YAQPTPATAA AYSDSYGRVY AADPYHHALA PAPTYGVGAM
410 420
PQGSSPSTDF RGAKLHTSRP LLSGS
Length:425
Mass (Da):45,950
Last modified:March 3, 2009 - v1
Checksum:iE03E6ABD235979C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005347 Genomic DNA No translation available.
AC005364 Genomic DNA No translation available.
AC005563 Genomic DNA No translation available.
AC005569 Genomic DNA No translation available.
AC005737 Genomic DNA No translation available.
AC012175 Genomic DNA No translation available.
AC023822 Genomic DNA No translation available.
AC074051 Genomic DNA No translation available.
KF495794 Genomic DNA No translation available.
AK293951 mRNA Translation: BAH11633.1
RefSeqiNP_001295046.1, NM_001308117.1
UniGeneiHs.459842

Genome annotation databases

EnsembliENST00000422070; ENSP00000391269; ENSG00000078328
GeneIDi54715
UCSCiuc010uxz.1 human

Similar proteinsi

Entry informationi

Entry nameiB7Z1U7_HUMAN
AccessioniPrimary (citable) accession number: B7Z1U7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 18, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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