UniProtKB - B7Z1I7 (B7Z1I7_HUMAN)
Protein
Submitted name:
Nik-related protein kinase
Gene
NRK
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- kinase activity Source: UniProtKB-KW
Keywordsi
Molecular function | KinaseImported, Transferase |
Names & Taxonomyi
Protein namesi | Submitted name: Nik-related protein kinaseImportedSubmitted name: cDNA FLJ50079, highly similar to Homo sapiens Nik related kinase (NRK), mRNAImported |
Gene namesi | Name:NRKImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:25391, NRK |
VEuPathDBi | HostDB:ENSG00000123572.16 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 12 – 32 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 38 – 57 | HelicalSequence analysisAdd BLAST | 20 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000123572, Expressed in metanephros and 153 other tissues |
ExpressionAtlasi | B7Z1I7, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 42 – 129 | CNHInterPro annotationAdd BLAST | 88 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000161533 |
HOGENOMi | CLU_1626448_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR001180, CNH_dom |
Pfami | View protein in Pfam PF00780, CNH, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
B7Z1I7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQVPRERIKI AFRLWIPILV IRIVVAGTWP QAPGLSTLGL NIIILPDCLG
60 70 80 90 100
IGMMLTFNAE ALSVEANEQL FKKILEMWKD IPSSIAFECT QRTTGWGQKA
110 120 130 140 150
IEVRSLQSRV LESELKRRSI KKLRFLCTRG DKLFFTSTLR NHHSRVYFMT
160
LGKLEELQSN YDV
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ7Z2Y5 | NRK_HUMAN | Nik-related protein kinase | NRK | 1,582 | Annotation score: | ||
F5H049 | F5H049_HUMAN | Nik-related protein kinase | NRK | 355 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | KF459286 Genomic DNA No translation available. KF459287 Genomic DNA No translation available. KF510615 Genomic DNA No translation available. Z68339 Genomic DNA No translation available. Z69734 Genomic DNA No translation available. Z70274 Genomic DNA No translation available. Z97356 Genomic DNA No translation available. AK293500 mRNA Translation: BAH11523.1 |
Genome annotation databases
Ensembli | ENST00000540278; ENSP00000438148; ENSG00000123572 |
UCSCi | uc011msi.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | KF459286 Genomic DNA No translation available. KF459287 Genomic DNA No translation available. KF510615 Genomic DNA No translation available. Z68339 Genomic DNA No translation available. Z69734 Genomic DNA No translation available. Z70274 Genomic DNA No translation available. Z97356 Genomic DNA No translation available. AK293500 mRNA Translation: BAH11523.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PRIDEi | B7Z1I7 |
ProteomicsDBi | 6335 |
Protocols and materials databases
Antibodypediai | 2074, 61 antibodies |
Genome annotation databases
Ensembli | ENST00000540278; ENSP00000438148; ENSG00000123572 |
UCSCi | uc011msi.3, human |
Organism-specific databases
HGNCi | HGNC:25391, NRK |
OpenTargetsi | ENSG00000123572 |
VEuPathDBi | HostDB:ENSG00000123572.16 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000161533 |
HOGENOMi | CLU_1626448_0_0_1 |
Miscellaneous databases
ChiTaRSi | NRK, human |
Gene expression databases
Bgeei | ENSG00000123572, Expressed in metanephros and 153 other tissues |
ExpressionAtlasi | B7Z1I7, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR001180, CNH_dom |
Pfami | View protein in Pfam PF00780, CNH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B7Z1I7_HUMAN | |
Accessioni | B7Z1I7Primary (citable) accession number: B7Z1I7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 3, 2009 |
Last sequence update: | March 3, 2009 | |
Last modified: | February 10, 2021 | |
This is version 72 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |