UniProtKB - B7UQR2 (B7UQR2_ECO27)
Protein
Regulator of ribonuclease activity B
Gene
rraB
Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Status
Functioni
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.UniRule annotation
GO - Molecular functioni
- endoribonuclease inhibitor activity Source: UniProtKB-UniRule
- enzyme binding Source: UniProtKB-UniRule
Names & Taxonomyi
Protein namesi | Recommended name: Regulator of ribonuclease activity BUniRule annotation |
Gene namesi | Name:rraBUniRule annotationImported Ordered Locus Names:E2348C_4579Imported |
Organismi | Escherichia coli O127:H6 (strain E2348/69 / EPEC)Imported |
Taxonomic identifieri | 574521 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmUniRule annotationARBA annotationInteractioni
Subunit structurei
Interacts with the C-terminal region of Rne.
UniRule annotationGO - Molecular functioni
- enzyme binding Source: UniProtKB-UniRule
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 12 – 113 | RraBInterPro annotationAdd BLAST | 102 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 114 – 138 | DisorderedSequence analysisAdd BLAST | 25 |
Sequence similaritiesi
Belongs to the RraB family.UniRule annotation
Phylogenomic databases
HOGENOMi | CLU_128640_0_0_6 |
OMAi | FCFDAIA |
Family and domain databases
Gene3Di | 3.30.70.970, 1 hit |
HAMAPi | MF_01888, RraB, 1 hit |
InterProi | View protein in InterPro IPR016716, RraB IPR036701, RraB-like_sf IPR009671, RraB_dom |
Pfami | View protein in Pfam PF06877, RraB, 1 hit |
PIRSFi | PIRSF018193, UCP018193, 1 hit |
SUPFAMi | SSF89946, SSF89946, 1 hit |
i Sequence
Sequence statusi: Complete.
B7UQR2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MANPEQLEEQ REETRLIIEE LLEDGSDPDA LYTIEHHLSA DDLETLEKAA
60 70 80 90 100
VEAFKLGYEV TDPEELEVED GDIVICCDIL SECALNADLI DAQVEQLMTL
110 120 130
AEKFDVEYDG WGTYFEDPNG EDGDDEDFVD EDDDGVRH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FM180568 Genomic DNA Translation: CAS12127.1 |
RefSeqi | WP_000002953.1, NC_011601.1 |
Genome annotation databases
EnsemblBacteriai | CAS12127; CAS12127; E2348C_4579 |
GeneIDi | 49586360 |
KEGGi | ecg:E2348C_4579 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FM180568 Genomic DNA Translation: CAS12127.1 |
RefSeqi | WP_000002953.1, NC_011601.1 |
3D structure databases
SMRi | B7UQR2 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | CAS12127; CAS12127; E2348C_4579 |
GeneIDi | 49586360 |
KEGGi | ecg:E2348C_4579 |
Phylogenomic databases
HOGENOMi | CLU_128640_0_0_6 |
OMAi | FCFDAIA |
Family and domain databases
Gene3Di | 3.30.70.970, 1 hit |
HAMAPi | MF_01888, RraB, 1 hit |
InterProi | View protein in InterPro IPR016716, RraB IPR036701, RraB-like_sf IPR009671, RraB_dom |
Pfami | View protein in Pfam PF06877, RraB, 1 hit |
PIRSFi | PIRSF018193, UCP018193, 1 hit |
SUPFAMi | SSF89946, SSF89946, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B7UQR2_ECO27 | |
Accessioni | B7UQR2Primary (citable) accession number: B7UQR2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 10, 2009 |
Last sequence update: | February 10, 2009 | |
Last modified: | December 2, 2020 | |
This is version 54 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |