UniProtKB - B7UQI1 (HFQ_ECO27)
Protein
RNA-binding protein Hfq
Gene
hfq
Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Status
Functioni
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.UniRule annotation
GO - Molecular functioni
- RNA binding Source: UniProtKB-UniRule
GO - Biological processi
- regulation of transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | RNA-binding |
Biological process | Stress response |
Names & Taxonomyi
Protein namesi | Recommended name: RNA-binding protein HfqUniRule annotation |
Gene namesi | Name:hfqUniRule annotation Ordered Locus Names:E2348C_4495 |
Organismi | Escherichia coli O127:H6 (strain E2348/69 / EPEC) |
Taxonomic identifieri | 574521 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000135031 | 1 – 102 | RNA-binding protein HfqAdd BLAST | 102 |
Interactioni
Subunit structurei
Homohexamer.
UniRule annotationFamily & Domainsi
Sequence similaritiesi
Belongs to the Hfq family.UniRule annotation
Phylogenomic databases
HOGENOMi | CLU_113688_2_1_6 |
OMAi | QQMVYKH |
Family and domain databases
CDDi | cd01716, Hfq, 1 hit |
HAMAPi | MF_00436, Hfq, 1 hit |
InterProi | View protein in InterPro IPR005001, Hfq IPR010920, LSM_dom_sf |
PANTHERi | PTHR34772, PTHR34772, 1 hit |
Pfami | View protein in Pfam PF17209, Hfq, 1 hit |
SUPFAMi | SSF50182, SSF50182, 1 hit |
TIGRFAMsi | TIGR02383, Hfq, 1 hit |
i Sequence
Sequence statusi: Complete.
B7UQI1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKGQSLQDP FLNALRRERV PVSIYLVNGI KLQGQIESFD QFVILLKNTV
60 70 80 90 100
SQMVYKHAIS TVVPSRPVSH HSNNAGGGTS SNYHHGSSAQ NTSAQQDSEE
TE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FM180568 Genomic DNA Translation: CAS12043.1 |
RefSeqi | WP_001051883.1, NC_011601.1 |
Genome annotation databases
EnsemblBacteriai | CAS12043; CAS12043; E2348C_4495 |
GeneIDi | 52078547 |
KEGGi | ecg:E2348C_4495 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FM180568 Genomic DNA Translation: CAS12043.1 |
RefSeqi | WP_001051883.1, NC_011601.1 |
3D structure databases
SMRi | B7UQI1 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | CAS12043; CAS12043; E2348C_4495 |
GeneIDi | 52078547 |
KEGGi | ecg:E2348C_4495 |
Phylogenomic databases
HOGENOMi | CLU_113688_2_1_6 |
OMAi | QQMVYKH |
Family and domain databases
CDDi | cd01716, Hfq, 1 hit |
HAMAPi | MF_00436, Hfq, 1 hit |
InterProi | View protein in InterPro IPR005001, Hfq IPR010920, LSM_dom_sf |
PANTHERi | PTHR34772, PTHR34772, 1 hit |
Pfami | View protein in Pfam PF17209, Hfq, 1 hit |
SUPFAMi | SSF50182, SSF50182, 1 hit |
TIGRFAMsi | TIGR02383, Hfq, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | HFQ_ECO27 | |
Accessioni | B7UQI1Primary (citable) accession number: B7UQI1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 28, 2009 |
Last sequence update: | February 10, 2009 | |
Last modified: | December 2, 2020 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |