UniProtKB - B7UJZ2 (FIS_ECO27)
Protein
DNA-binding protein Fis
Gene
fis
Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Status
Functioni
Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.UniRule annotation
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 74 – 93 | H-T-H motifUniRule annotationAdd BLAST | 20 |
GO - Molecular functioni
- DNA-binding transcription factor activity Source: UniProtKB-UniRule
- sequence-specific DNA binding Source: InterPro
Keywordsi
Molecular function | Activator, DNA-binding |
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: DNA-binding protein FisUniRule annotation |
Gene namesi | Name:fisUniRule annotation Ordered Locus Names:E2348C_3531 |
Organismi | Escherichia coli O127:H6 (strain E2348/69 / EPEC) |
Taxonomic identifieri | 574521 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000123605 | 1 – 98 | DNA-binding protein FisAdd BLAST | 98 |
Interactioni
Subunit structurei
Homodimer.
UniRule annotationFamily & Domainsi
Sequence similaritiesi
Belongs to the transcriptional regulatory Fis family.UniRule annotation
Phylogenomic databases
HOGENOMi | CLU_158040_3_0_6 |
OMAi | MVLCEVE |
Family and domain databases
HAMAPi | MF_00166, DNA_binding_Fis, 1 hit |
InterProi | View protein in InterPro IPR005412, Fis_DNA-bd IPR009057, Homeobox-like_sf IPR002197, HTH_Fis |
Pfami | View protein in Pfam PF02954, HTH_8, 1 hit |
PIRSFi | PIRSF002097, DNA-binding_Fis, 1 hit |
PRINTSi | PR01591, DNABINDNGFIS PR01590, HTHFIS |
SUPFAMi | SSF46689, SSF46689, 1 hit |
i Sequence
Sequence statusi: Complete.
B7UJZ2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFEQRVNSDV LTVSTVNSQD QVTQKPLRDS VKQALKNYFA QLNGQDVNDL
60 70 80 90
YELVLAEVEQ PLLDMVMQYT RGNQTRAALM MGINRGTLRK KLKKYGMN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FM180568 Genomic DNA Translation: CAS11079.1 |
RefSeqi | WP_000462905.1, NC_011601.1 |
Genome annotation databases
EnsemblBacteriai | CAS11079; CAS11079; E2348C_3531 |
GeneIDi | 9127117 |
KEGGi | ecg:E2348C_3531 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FM180568 Genomic DNA Translation: CAS11079.1 |
RefSeqi | WP_000462905.1, NC_011601.1 |
3D structure databases
SMRi | B7UJZ2 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | CAS11079; CAS11079; E2348C_3531 |
GeneIDi | 9127117 |
KEGGi | ecg:E2348C_3531 |
Phylogenomic databases
HOGENOMi | CLU_158040_3_0_6 |
OMAi | MVLCEVE |
Family and domain databases
HAMAPi | MF_00166, DNA_binding_Fis, 1 hit |
InterProi | View protein in InterPro IPR005412, Fis_DNA-bd IPR009057, Homeobox-like_sf IPR002197, HTH_Fis |
Pfami | View protein in Pfam PF02954, HTH_8, 1 hit |
PIRSFi | PIRSF002097, DNA-binding_Fis, 1 hit |
PRINTSi | PR01591, DNABINDNGFIS PR01590, HTHFIS |
SUPFAMi | SSF46689, SSF46689, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | FIS_ECO27 | |
Accessioni | B7UJZ2Primary (citable) accession number: B7UJZ2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 28, 2009 |
Last sequence update: | February 10, 2009 | |
Last modified: | December 2, 2020 | |
This is version 65 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |