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Protein

Glutathione-regulated potassium-efflux system ancillary protein KefG

Gene

kefG

Organism
Escherichia coli O7:K1 (strain IAI39 / ExPEC)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.UniRule annotation

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

BioCyciECOL585057:ECIAI39_3833-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione-regulated potassium-efflux system ancillary protein KefGUniRule annotation
Alternative name(s):
Putative quinone oxidoreductase KefGUniRule annotation (EC:1.6.5.2UniRule annotation)
Gene namesi
Name:kefGUniRule annotation
Ordered Locus Names:ECIAI39_3833
OrganismiEscherichia coli O7:K1 (strain IAI39 / ExPEC)
Taxonomic identifieri585057 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000749 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001455731 – 184Glutathione-regulated potassium-efflux system ancillary protein KefGAdd BLAST184

Interactioni

Subunit structurei

Interacts with KefB.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7NMB9
SMRiB7NMB9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000149972
KOiK11748
OMAiRYPMSDI

Family and domain databases

Gene3Di3.40.50.360, 1 hit
HAMAPiMF_01415 K_H_efflux_KefG, 1 hit
InterProiView protein in InterPro
IPR003680 Flavodoxin_fold
IPR029039 Flavoprotein-like_sf
IPR023947 K_H_efflux_KefG
PfamiView protein in Pfam
PF02525 Flavodoxin_2, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit

Sequencei

Sequence statusi: Complete.

B7NMB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSQPAKVLL LYAHPESQDS VANRVLLKPA TQLSNVTVHD LYAHYPDFFI
60 70 80 90 100
DIPREQALLR EHEVIVFQHP LYTYSCPALL KEWLDRVLSR GFASGPGGNQ
110 120 130 140 150
LAGKYWRSVI TTGEPESAYR YDALNRYPMS DVLRPFELAA GMCRMHWLSP
160 170 180
IIIYWARRQS AQELASHARA YGDWLANPLS PGGR
Length:184
Mass (Da):20,958
Last modified:March 24, 2009 - v1
Checksum:iF3B1123F7378EAB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928164 Genomic DNA Translation: CAR19947.1
RefSeqiWP_000987657.1, NC_011750.1
YP_002409728.1, NC_011750.1

Genome annotation databases

EnsemblBacteriaiCAR19947; CAR19947; ECIAI39_3833
GeneIDi7151894
KEGGiect:ECIAI39_3833
PATRICifig|585057.6.peg.3970

Similar proteinsi

Entry informationi

Entry nameiKEFG_ECO7I
AccessioniPrimary (citable) accession number: B7NMB9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 24, 2009
Last modified: June 20, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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