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Protein

L-fuculokinase

Gene

fucK

Organism
Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of L-fuculose.UniRule annotation

Catalytic activityi

ATP + L-fuculose = ADP + L-fuculose 1-phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotation

Pathwayi: L-fucose degradation

This protein is involved in step 2 of the subpathway that synthesizes L-lactaldehyde and glycerone phosphate from L-fucose.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. L-fucose isomerase (fucI)
  2. L-fuculokinase (fucK)
  3. L-fuculose phosphate aldolase (fucA), L-fuculose phosphate aldolase (mtnB)
This subpathway is part of the pathway L-fucose degradation, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-lactaldehyde and glycerone phosphate from L-fucose, the pathway L-fucose degradation and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
Biological processCarbohydrate metabolism, Fucose metabolismUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00563; UER00625

Names & Taxonomyi

Protein namesi
Recommended name:
L-fuculokinaseUniRule annotation (EC:2.7.1.51UniRule annotation)
Alternative name(s):
L-fuculose kinaseUniRule annotation
Gene namesi
Name:fucKUniRule annotationImported
Ordered Locus Names:ECUMN_3132Imported
OrganismiEscherichia coli O17:K52:H18 (strain UMN026 / ExPEC)Imported
Taxonomic identifieri585056 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000007097 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliB7N737
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 259FGGY_NInterPro annotationAdd BLAST245
Domaini269 – 448FGGY_CInterPro annotationAdd BLAST180

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili377 – 397Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the FGGY kinase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000124178
KOiK00879
OMAiKKGRIFC

Family and domain databases

HAMAPiMF_00986 Fuculokinase, 1 hit
InterProiView protein in InterPro
IPR000577 Carb_kinase_FGGY
IPR018485 Carb_kinase_FGGY_C
IPR018483 Carb_kinase_FGGY_CS
IPR018484 Carb_kinase_FGGY_N
IPR013450 Fuculokinase
PANTHERiPTHR10196:SF60 PTHR10196:SF60, 1 hit
PfamiView protein in Pfam
PF02782 FGGY_C, 1 hit
PF00370 FGGY_N, 1 hit
PIRSFiPIRSF000538 GlpK, 1 hit
TIGRFAMsiTIGR02628 fuculo_kin_coli, 1 hit
PROSITEiView protein in PROSITE
PS00933 FGGY_KINASES_1, 1 hit
PS00445 FGGY_KINASES_2, 1 hit

Sequencei

Sequence statusi: Complete.

B7N737-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSGYIAGAI MKQEVILVLD CGATNVRAIA VNRQGKIVAR ASTPNASDIA
60 70 80 90 100
MENNTWHQWS LDAILQRFAD CCRQINSELT DCHIRGIAVT TFGVDGALVD
110 120 130 140 150
KQGNLLYPII SWKCPRTAAV MDNIERLISA QQLQAISGVG AFSFNTLYKL
160 170 180 190 200
VWLKENHPQL LERAHAWLFI SSLINHRLTG EFTTDITMAG TSQMLDIQQR
210 220 230 240 250
DFSPQILQAT GIPRRLFPRL VEAGEQIGTL QNSAAAMLGL PVGIPVISAG
260 270 280 290 300
HDTQFALFGA GADQNEPVLS SGTWEILMVR SAQVDTSLLS QYAGSTCELD
310 320 330 340 350
SQAGLYNPGM QWLASGVLEW VRKLFWTAET PWQMLIEEAR LIAPGADGVK
360 370 380 390 400
MQCDLLSCQN AGWQGVTLNT TRGHFYRAAL EGLTAQLQRN LQMLEKIGHF
410 420 430 440 450
KASELLLVGG GSRNTLWNQI KANMLDIPVK VLDDAETTVA GAALFGWYGV
460 470 480
GEFNSPEEAR AQIHYQYRYF YPQTEPEFIE EV
Length:482
Mass (Da):53,180
Last modified:February 10, 2009 - v1
Checksum:iDD8E2AF291F619ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928163 Genomic DNA Translation: CAR14298.1
RefSeqiYP_002413818.2, NC_011751.1

Genome annotation databases

EnsemblBacteriaiCAR14298; CAR14298; ECUMN_3132
GeneIDi7156470
KEGGieum:ECUMN_3132
PATRICifig|585056.7.peg.3314

Similar proteinsi

Entry informationi

Entry nameiB7N737_ECOLU
AccessioniPrimary (citable) accession number: B7N737
Entry historyiIntegrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: March 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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