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Protein

N-acetyl-D-glucosamine kinase

Gene

nagK

Organism
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.UniRule annotation

Catalytic activityi

ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate.UniRule annotation

Pathwayi: peptidoglycan recycling

This protein is involved in the pathway peptidoglycan recycling, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan recycling and in Cell wall biogenesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi157ZincUniRule annotation1
Metal bindingi177ZincUniRule annotation1
Metal bindingi179ZincUniRule annotation1
Metal bindingi184ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi4 – 11ATPUniRule annotation8
Nucleotide bindingi133 – 140ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processCarbohydrate metabolism
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCyciEFER585054:EFER_RS06490-MONOMER
UniPathwayiUPA00544

Names & Taxonomyi

Protein namesi
Recommended name:
N-acetyl-D-glucosamine kinaseUniRule annotation (EC:2.7.1.59UniRule annotation)
Alternative name(s):
GlcNAc kinaseUniRule annotation
Gene namesi
Name:nagKUniRule annotation
Ordered Locus Names:EFER_1283
OrganismiEscherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Taxonomic identifieri585054 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000745 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001401891 – 303N-acetyl-D-glucosamine kinaseAdd BLAST303

Proteomic databases

PRIDEiB7LPQ4

Structurei

3D structure databases

ProteinModelPortaliB7LPQ4
SMRiB7LPQ4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ROK (NagC/XylR) family. NagK subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000150087
KOiK00884
OMAiLQLNYHA
OrthoDBiPOG091H07RB

Family and domain databases

HAMAPiMF_01271 GlcNAc_kinase, 1 hit
InterProiView protein in InterPro
IPR023505 N-acetyl-D-glucosamine_kinase
IPR000600 ROK
PANTHERiPTHR18964 PTHR18964, 1 hit
PfamiView protein in Pfam
PF00480 ROK, 1 hit
PROSITEiView protein in PROSITE
PS01125 ROK, 1 hit

Sequencei

Sequence statusi: Complete.

B7LPQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYYGFDIGGT KIALGVFDSG RQLQWEKRVP TPRDSYDAFL DAVCELVAEA
60 70 80 90 100
DQRFGCKGSV GIGIPGMPET EDGTLYAANV PAASGKPLRA DLSARLDRDV
110 120 130 140 150
RLDNDANCFA LSEAWDDEFT QYPLVMGLIL GTGVGGGLIF NGKPITGKSY
160 170 180 190 200
ITGEFGHMRL PVDALTMMGL DFPLRRCGCG QIGCIENYLS GRGFAWLWQH
210 220 230 240 250
YYHQPLQAPE IIALWEEGDE RAQAHVDRYL DLLAVCLGNI LTIVDPDLVV
260 270 280 290 300
IGGGLSNFTA ITTQLADRLP RHLLPVARVP RIERARHGDA GGMRGAAFLH

LSD
Length:303
Mass (Da):33,056
Last modified:February 10, 2009 - v1
Checksum:i1394E3FA654ECAB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928158 Genomic DNA Translation: CAQ88807.1
RefSeqiWP_000291279.1, NC_011740.1

Genome annotation databases

EnsemblBacteriaiCAQ88807; CAQ88807; EFER_1283
KEGGiefe:EFER_1283

Similar proteinsi

Entry informationi

Entry nameiNAGK_ESCF3
AccessioniPrimary (citable) accession number: B7LPQ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: June 20, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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