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Protein

50S ribosomal protein L5

Gene

rplE

Organism
Escherichia coli (strain 55989 / EAEC)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L5UniRule annotation
Gene namesi
Name:rplEUniRule annotation
Ordered Locus Names:EC55989_3724
OrganismiEscherichia coli (strain 55989 / EAEC)
Taxonomic identifieri585055 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000746 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001661321 – 17950S ribosomal protein L5Add BLAST179

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei3N6-acetyllysineUniRule annotation1

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiB7L4J7

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7L4J7
SMRiB7L4J7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL5 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231311
KOiK02931
OMAiEQVMFHE

Family and domain databases

Gene3Di3.30.1440.10, 1 hit
HAMAPiMF_01333_B Ribosomal_L5_B, 1 hit
InterProiView protein in InterPro
IPR002132 Ribosomal_L5
IPR020930 Ribosomal_L5_bac-type
IPR031309 Ribosomal_L5_C
IPR020929 Ribosomal_L5_CS
IPR022803 Ribosomal_L5_dom_sf
IPR031310 Ribosomal_L5_N
PANTHERiPTHR11994 PTHR11994, 1 hit
PfamiView protein in Pfam
PF00281 Ribosomal_L5, 1 hit
PF00673 Ribosomal_L5_C, 1 hit
PIRSFiPIRSF002161 Ribosomal_L5, 1 hit
SUPFAMiSSF55282 SSF55282, 1 hit
PROSITEiView protein in PROSITE
PS00358 RIBOSOMAL_L5, 1 hit

Sequencei

Sequence statusi: Complete.

B7L4J7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKLHDYYKD EVVKKLMTEF NYNSVMQVPR VEKITLNMGV GEAIADKKLL
60 70 80 90 100
DNAAADLAAI SGQKPLITKA RKSVAGFKIR QGYPIGCKVT LRGERMWEFF
110 120 130 140 150
ERLITIAVPR IRDFRGLSAK SFDGRGNYSM GVREQIIFPE IDYDKVDRVR
160 170
GLDITITTTA KSDEEGRALL AAFDFPFRK
Length:179
Mass (Da):20,302
Last modified:February 10, 2009 - v1
Checksum:iB2E95A8BE4B8D2A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928145 Genomic DNA Translation: CAV00017.1
RefSeqiWP_001096200.1, NC_011748.1

Genome annotation databases

EnsemblBacteriaiCAV00017; CAV00017; EC55989_3724
GeneIDi32369203
KEGGieck:EC55989_3724

Similar proteinsi

Entry informationi

Entry nameiRL5_ECO55
AccessioniPrimary (citable) accession number: B7L4J7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 10, 2009
Last modified: November 22, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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