UniProtKB - B7FU22 (B7FU22_PHATC)
Protein
Peptidyl-prolyl cis-trans isomerase
Gene
PHATRDRAFT_44426
Organism
Phaeodactylum tricornutum (strain CCAP 1055/1)
Status
Functioni
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.UniRule annotation
Catalytic activityi
- [protein]-peptidylproline (ω=180) = [protein]-peptidylproline (ω=0)UniRule annotationARBA annotationEC:5.2.1.8UniRule annotationARBA annotation
GO - Molecular functioni
- peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-UniRule
- RNA binding Source: UniProtKB-UniRule
Keywordsi
Molecular function | Isomerase, RNA-bindingPROSITE-ProRule annotation, RotamaseUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Peptidyl-prolyl cis-trans isomeraseUniRule annotation (EC:5.2.1.8UniRule annotation)Short name: PPIaseUniRule annotation |
Gene namesi | ORF Names:PHATRDRAFT_44426Imported |
Organismi | Phaeodactylum tricornutum (strain CCAP 1055/1)Imported |
Taxonomic identifieri | 556484 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Stramenopiles › Ochrophyta › Bacillariophyta › Bacillariophyceae › Bacillariophycidae › Naviculales › Phaeodactylaceae › Phaeodactylum › |
Proteomesi |
|
Subcellular locationi
- Nucleus UniRule annotation
GO - Cellular componenti
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusUniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 25 – 216 | PPIase cyclophilin-typeInterPro annotationAdd BLAST | 192 | |
Domaini | 315 – 393 | RRMInterPro annotationAdd BLAST | 79 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 404 – 638 | DisorderedSequence analysisAdd BLAST | 235 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 465 – 584 | PolyampholyteSequence analysisAdd BLAST | 120 | |
Compositional biasi | 591 – 627 | PolyampholyteSequence analysisAdd BLAST | 37 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG0415, Eukaryota |
HOGENOMi | CLU_018791_2_1_1 |
InParanoidi | B7FU22 |
OMAi | LPRIHHS |
OrthoDBi | 1436035at2759 |
Family and domain databases
Gene3Di | 2.40.100.10, 1 hit 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR035542, CRIP IPR029000, Cyclophilin-like_dom_sf IPR002130, Cyclophilin-type_PPIase_dom IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
PANTHERi | PTHR45843, PTHR45843, 1 hit |
Pfami | View protein in Pfam PF00160, Pro_isomerase, 1 hit PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF50891, SSF50891, 1 hit SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50072, CSA_PPIASE_2, 1 hit PS50102, RRM, 1 hit |
i Sequence
Sequence statusi: Complete.
B7FU22-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNGGLTLRLA REGSIKNLTM AVLLETDVGD MVIDLDVEGS PELSRNLLKL
60 70 80 90 100
CKARYYTKTL IYNVNSRFCQ AGDPIGDGTG GGCMYGLLDQ HSSSPLADIR
110 120 130 140 150
QSQRRFLKGK GRKLSASECR EKGRVVATEL NGVPDTIGSQ FLITLESGEG
160 170 180 190 200
RALDGYVRSS IVSDEASKES GKSVSSFLSL GTVTEDVDGA LDKIAASYCD
210 220 230 240 250
PDGRPYADIR IIRALVIHDP FDDPEGMDEL LAKRDVVVHA ESGRVTSSPS
260 270 280 290 300
PERPVEEAVA VRIPISQIEP DEEGLTEVEL RRREEQAQKQ EDRGRAVVLE
310 320 330 340 350
MLGDLPDADI KAPENVLFIC KLNPITQDED LELIFSRFDP TVKVEIIRDQ
360 370 380 390 400
STGKSLQYAF AEFEEKQQAV EAYFKMNNAL VDDRRIKVDF SQSVSKIWNK
410 420 430 440 450
YTQKMRMPTG GPGGTFQNSA STGPGVSRGR GGRHSCQGGN WQVRNDDRHR
460 470 480 490 500
PSERSDMRSY YGSPNRSNDD RHRDSRRSAD ARKMDWQRDH RDKRERQRSD
510 520 530 540 550
DPSSHSKGDR NGSRHRGRAG DGDRRKRDER THEDRENDRE RHYHTERDAG
560 570 580 590 600
RIDDGRSHSV RREYDRVERK RKDRTGYDDN YHRRSKSSHR HRDEGHKERR
610 620 630
RDKERSYSGE DSHRKSEHRD RDHERSRRDS KRKRRSRS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CM000607 Genomic DNA Translation: EEC50192.1 |
RefSeqi | XP_002178527.1, XM_002178491.1 |
Genome annotation databases
EnsemblProtistsi | Phatr3_J44426.t1; Phatr3_J44426.p1; Phatr3_J44426 |
GeneIDi | 7197667 |
KEGGi | pti:PHATRDRAFT_44426 |
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CM000607 Genomic DNA Translation: EEC50192.1 |
RefSeqi | XP_002178527.1, XM_002178491.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 2850.Phatr44426 |
Genome annotation databases
EnsemblProtistsi | Phatr3_J44426.t1; Phatr3_J44426.p1; Phatr3_J44426 |
GeneIDi | 7197667 |
KEGGi | pti:PHATRDRAFT_44426 |
Phylogenomic databases
eggNOGi | KOG0415, Eukaryota |
HOGENOMi | CLU_018791_2_1_1 |
InParanoidi | B7FU22 |
OMAi | LPRIHHS |
OrthoDBi | 1436035at2759 |
Family and domain databases
Gene3Di | 2.40.100.10, 1 hit 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR035542, CRIP IPR029000, Cyclophilin-like_dom_sf IPR002130, Cyclophilin-type_PPIase_dom IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
PANTHERi | PTHR45843, PTHR45843, 1 hit |
Pfami | View protein in Pfam PF00160, Pro_isomerase, 1 hit PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF50891, SSF50891, 1 hit SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50072, CSA_PPIASE_2, 1 hit PS50102, RRM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B7FU22_PHATC | |
Accessioni | B7FU22Primary (citable) accession number: B7FU22 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 10, 2009 |
Last sequence update: | February 10, 2009 | |
Last modified: | December 2, 2020 | |
This is version 67 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |