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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Wolbachia endosymbiont of Culex quinquefasciatus JHB
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi482MagnesiumUniRule annotation1
Metal bindingi488MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotation, RNA-bindingUniRule annotation, Transferase
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotationImported
ORF Names:C1A_403Imported
OrganismiWolbachia endosymbiont of Culex quinquefasciatus JHBImported
Taxonomic identifieri569881 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeWolbachieaeWolbachia
Proteomesi
  • UP000004540 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini618 – 686S1 motifInterPro annotationAdd BLAST69

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili238 – 258Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

OrthoDBiPOG091H00M0

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 2 hits
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

B6Y6D3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFEIIKKSID WEGRTLSLET GKIARQADGS VVVKLWRYFY LSHCCTKKKE
60 70 80 90 100
ESVDFLPLNV QFIAKSYAMG KIPGGFFKRE GKPSDRETLI SRVIDRSIRP
110 120 130 140 150
LFPEGFHDEI SVVCNLLTYD TVNSPEVPAL IGTVAALAIS GVPFHFTIAG
160 170 180 190 200
VMVGCDENNN YILNPSVQEM KASNLDLFLS GDENSILMVE SEVKELSEEN
210 220 230 240 250
VLNAIKFGHE HLQPVIKLIK EFADTVGNKP ESFAPVDISD ITQELEKYRK
260 270 280 290 300
DFEEAYSKTV KQERVQALEV VRNNILNTLK EAGKDEKLIT YAVKSFERSL
310 320 330 340 350
VREMIRRKSV RIDSRKYDEI RQIEIEADIL PKTHGSALFT RGSTQALVVT
360 370 380 390 400
ALGTTQDEQI VDDIEGDRRE HFMLHYNFPP FAVGEASAIR APGRREIGHG
410 420 430 440 450
KLAWKAIHPV LPDKSEFPYT IRVVSEIMES DGSSSMATVC GTSIALMDTG
460 470 480 490 500
VPIKAPVAGI AMGLIKDKNE HIILSDILGD EDYLGDMDFK VAGTSEGITA
510 520 530 540 550
LQMDMKIPGI SFEIVEKSLE QAKVGRLHIL EKMNAVISEH RKDIKDHVPR
560 570 580 590 600
VLSFYIDKDK ISAAIGTKGK NIRSVCERSN AKIEIGDDGK VSVFAISSTE
610 620 630 640 650
AEAAKNMMID SITELEQGSI IDAKVVKIEK SIVELELLNG RKGKMHISEV
660 670 680 690 700
ANQHVESIED ILKQGDTFKA LIIDFEKGGC PKLSRRRVDQ ETGEFFEGKL
710 720 730 740 750
YNEERRDGLN NRDNYYNNSF NKKPEDNYHS NRPTRPRSGF SNRSRPKFGN

NDSSSGFY
Length:758
Mass (Da):84,947
Last modified:January 20, 2009 - v1
Checksum:i02EBD94C27461178
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABZA01000001 Genomic DNA Translation: EEB56221.1
RefSeqiWP_007302238.1, NZ_DS996942.1

Genome annotation databases

EnsemblBacteriaiEEB56221; EEB56221; C1A_403

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABZA01000001 Genomic DNA Translation: EEB56221.1
RefSeqiWP_007302238.1, NZ_DS996942.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiEEB56221; EEB56221; C1A_403

Phylogenomic databases

OrthoDBiPOG091H00M0

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 2 hits
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB6Y6D3_9RICK
AccessioniPrimary (citable) accession number: B6Y6D3
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2009
Last sequence update: January 20, 2009
Last modified: February 28, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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