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Entry version 62 (17 Jun 2020)
Sequence version 1 (16 Dec 2008)
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Protein

Spermatogenesis-associated protein 31

Gene

Spata31

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in spermatogenesis.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDifferentiation, Spermatogenesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Spermatogenesis-associated protein 31
Alternative name(s):
Acrosome-expressed protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Spata31
Synonyms:Aep1, Vad1.3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Rat genome database

More...
RGDi
727950 Spata31

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei22 – 42HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cytoplasmic vesicle, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004205731 – 1048Spermatogenesis-associated protein 31Add BLAST1048

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
B6VQA5

PRoteomics IDEntifications database

More...
PRIDEi
B6VQA5

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
B6VQA5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
B6VQA5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Specifically expressed in testis by haploid germ cells.2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

First detected at day 25 postpartum, the expression increases until day 35 and remains identical till adulthood.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000018202 Expressed in testis and 1 other tissue

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
B6VQA5 RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

May interact with ACTB and the syntaxin STX1A and/or STX1B.

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000024504

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SPATA31 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IF6X Eukaryota
ENOG4111EH8 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183043

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005668_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
B6VQA5

Identification of Orthologs from Complete Genome Data

More...
OMAi
IQHPEWP

Database of Orthologous Groups

More...
OrthoDBi
1095565at2759

TreeFam database of animal gene trees

More...
TreeFami
TF338531

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039509 SPATA31/FAM205

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14650 FAM75, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B6VQA5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENLPSLLES IYTTWLSLSS TIWAMDMILA FVCGLGLYLL LLPFLESHLS
60 70 80 90 100
SSPSDINFTR KPQIQMTWQS QYMKKFRNHC RNDAKAWEEC LKKLKEKEKD
110 120 130 140 150
ELFLEEMSPG HHLNSLGNMF NSASAKQDST TLSPFWNLKE KSEEQMATQK
160 170 180 190 200
LSYPKISGDH LQEKYDQLYW GLPSLHSESL VAAAWIPQTT STLPSPFFLF
210 220 230 240 250
NVISSVYPIH LQDKMSPVLP HTHPLSYLDL QPPPLILSPL EFQSPALNQV
260 270 280 290 300
HFQSPLPVLL PSSLPYSRDS GACYSQSQSK PHCPTTEIQY RERPLVTKQL
310 320 330 340 350
ESRLTLPLMV QKDAYSILAS NPSHDWAVPI FPDNFPISCE LRDKLEQHIQ
360 370 380 390 400
KWFIQHQWYF PPEIQESEEV MGLQNSVTGN YQIRDQPCTS QAHMSTGEHN
410 420 430 440 450
KQGQKVKFQL ENESCKNLGP ILGKGPKDPV KGLEKNVVKV QGANILEPER
460 470 480 490 500
NLVKHFKSDS RNDSSNYIDE DLENNWKANF GTKSGQINQG LTPLSMRQSW
510 520 530 540 550
LAMNDSFCDT DIHMETRNLT AIKSSEKFMC SREKLAFLNP ETRQTLEEHV
560 570 580 590 600
VRFWVKHRWG LPLKMLKPIN LFKLKSTESL PLTLCTQPSS TNSVHRTNSA
610 620 630 640 650
VEVVRFLGKP CLRQIIIKDS SPPPGNLLLV SSPSCKRAAI RRPPSGVDHE
660 670 680 690 700
PSVALPNKPQ SAYLAETLAY NFMETPTQSG GVLKDEMETE EVLLLPRMTC
710 720 730 740 750
APNLRAHNPQ AKVVSEYPYN VETELTGQPQ IYTTSVLLPK HSRSMPLPVD
760 770 780 790 800
TLTSNALGDI VMVDGGNGLV QQRPSTPKHQ VSQKGQIKML VPTYQGEDTK
810 820 830 840 850
RQSERKYEDM SKFSPVTERK NNFENQYYQT LPKTTQVLPE SLFQRLLSRF
860 870 880 890 900
LPRVHPKKTI KGQECHPQKD NPTAATAQNQ RRQVRKQPYM DDNVTEAQKL
910 920 930 940 950
MTTVGQMLEK KMMQHQHHAS KVNQPRVVPP GPTSWFSHGH MPVSCLKRRR
960 970 980 990 1000
PPSYPANSLC QRRYIQGRHN RGQLPQKSVQ FSQKPQILRN PRHMYPKSAL
1010 1020 1030 1040
NVVNSSQNRT TVPRTPNQHL CCPRHCAFQR NVCRELGHPS VAFPNRKT
Length:1,048
Mass (Da):119,551
Last modified:December 16, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6917B272715EAC8D
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAP42847 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC085936 mRNA Translation: AAH85936.2
AF511042 mRNA Translation: AAP42847.2 Different initiation.

NCBI Reference Sequences

More...
RefSeqi
NP_001008360.2, NM_001008359.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000024504; ENSRNOP00000024504; ENSRNOG00000018202

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
353306

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:353306

UCSC genome browser

More...
UCSCi
RGD:727950 rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC085936 mRNA Translation: AAH85936.2
AF511042 mRNA Translation: AAP42847.2 Different initiation.
RefSeqiNP_001008360.2, NM_001008359.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000024504

PTM databases

iPTMnetiB6VQA5
PhosphoSitePlusiB6VQA5

Proteomic databases

PaxDbiB6VQA5
PRIDEiB6VQA5

Genome annotation databases

EnsembliENSRNOT00000024504; ENSRNOP00000024504; ENSRNOG00000018202
GeneIDi353306
KEGGirno:353306
UCSCiRGD:727950 rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
727905
RGDi727950 Spata31

Phylogenomic databases

eggNOGiENOG410IF6X Eukaryota
ENOG4111EH8 LUCA
GeneTreeiENSGT00950000183043
HOGENOMiCLU_005668_2_1_1
InParanoidiB6VQA5
OMAiIQHPEWP
OrthoDBi1095565at2759
TreeFamiTF338531

Miscellaneous databases

Protein Ontology

More...
PROi
PR:B6VQA5

Gene expression databases

BgeeiENSRNOG00000018202 Expressed in testis and 1 other tissue
GenevisibleiB6VQA5 RN

Family and domain databases

InterProiView protein in InterPro
IPR039509 SPATA31/FAM205
PfamiView protein in Pfam
PF14650 FAM75, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPT31_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B6VQA5
Secondary accession number(s): Q5U2N7, Q7TSL1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2013
Last sequence update: December 16, 2008
Last modified: June 17, 2020
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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