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Entry version 78 (29 Sep 2021)
Sequence version 1 (16 Dec 2008)
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Protein
Submitted name:

Ankyrin repeat-containing protein

Gene

BN1205_078640

Organism
Toxoplasma gondii (strain ATCC 50861 / VEG)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ankyrin repeat-containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:BN1205_078640Imported, TGVEG_255510Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiToxoplasma gondii (strain ATCC 50861 / VEG)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri432359 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaSarAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002226 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Partially assembled WGS sequence

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
ToxoDB:TGVEG_255510

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
B6KAP5

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati342 – 374ANKPROSITE-ProRule annotationAdd BLAST33
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini348 – 439Ankyrin_rpt-contain_domInterPro annotationAdd BLAST92
Repeati375 – 407ANKPROSITE-ProRule annotationAdd BLAST33
Repeati410 – 437ANKPROSITE-ProRule annotationAdd BLAST28
Repeati507 – 539ANKPROSITE-ProRule annotationAdd BLAST33
Domaini512 – 599Ankyrin_rpt-contain_domInterPro annotationAdd BLAST88
Repeati540 – 572ANKPROSITE-ProRule annotationAdd BLAST33
Domaini667 – 741RNA_GG_bindInterPro annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni28 – 116DisorderedSequence analysisAdd BLAST89
Regioni202 – 339DisorderedSequence analysisAdd BLAST138
Regioni452 – 498DisorderedSequence analysisAdd BLAST47
Regioni754 – 844DisorderedSequence analysisAdd BLAST91
Regioni857 – 886DisorderedSequence analysisAdd BLAST30
Regioni904 – 929DisorderedSequence analysisAdd BLAST26
Regioni1021 – 1158DisorderedSequence analysisAdd BLAST138

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi32 – 51Polar residuesSequence analysisAdd BLAST20
Compositional biasi202 – 241Basic and acidic residuesSequence analysisAdd BLAST40
Compositional biasi303 – 317Polar residuesSequence analysisAdd BLAST15
Compositional biasi455 – 490Basic and acidic residuesSequence analysisAdd BLAST36
Compositional biasi821 – 844Polar residuesSequence analysisAdd BLAST24
Compositional biasi1031 – 1064Basic and acidic residuesSequence analysisAdd BLAST34
Compositional biasi1072 – 1089Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi1105 – 1158Basic and acidic residuesSequence analysisAdd BLAST54

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4177, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
B6KAP5

Identification of Orthologs from Complete Genome Data

More...
OMAi
KREWRAE

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.1440, 1 hit
1.25.40.20, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR019385, PHAX_RNA-binding_domain
IPR038092, PHAX_RNA-binding_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796, Ank_2, 2 hits
PF10258, RNA_GG_bind, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403, SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50088, ANK_REPEAT, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B6KAP5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPHLLLPSC SSPCLPAGSP ETAEALLAAA TKSKSASKSP PATSSFSLAS
60 70 80 90 100
EASDAKPDAP MASCPPSDAA CPTAAPAASP PDENPRRTRA KPDVTPTACS
110 120 130 140 150
AGELPRPAAA PAFPSGSEVV TRFEPDAQIA EALLNGYRLS EDTAGDADFT
160 170 180 190 200
FPLDFQMPLN YEIYSFISQC LNATQLKQSL SEQGADAVPA VAKSLLAAGL
210 220 230 240 250
AKAREERRGG SCARERRESA ERTPKRTEEM SGQRKEPEEN AWPTLEAGAA
260 270 280 290 300
TQRRQLEKEN NERGQPARPA TGKQSKCRKQ WKVKEHNDRE ETPAASAPAE
310 320 330 340 350
TPGAPVSSDS ASPQTAQPAA LLGPAPLASP TVRAPPGLSG PDVNTALLRA
360 370 380 390 400
AFLGREDIVD LCLKRGGDVS FSDRVGRSAL HYGAATGTER IVRKLLEAGG
410 420 430 440 450
AKNINQRDRK HWTPLLIAVT KTHSACVRLL LEKGAEVGAT LCHRCAPCRS
460 470 480 490 500
SAQRAPETRE SEKSEKDGQA KDAAEAAEAN ASEKAEAKTD VKPSACGAGE
510 520 530 540 550
AEGPIQTWSA AIHFAAIKGN IEISKLLLDY GATVNDLDSD KRPPLHYAAC
560 570 580 590 600
RDNSHYVSWL LARGARLDLF DVNGRSALHA AAIKGQLQNA QSILEAADPV
610 620 630 640 650
TALLLLRRKD KWDITPAQLA KLHGQNGAFL LLKSYADQLE ATLGEHAALI
660 670 680 690 700
EPETADACLL NQTITEVLAT GMQEVKKNKL ERTVARLGTV TCLKAYQKTM
710 720 730 740 750
MVQGMGGMLV ADGSRPKTAG GVFFTLLREM ARQGEISRDD LVYIEMEDGE
760 770 780 790 800
AKKALRRRAR QKHSSSSGAE AAPRLPHRTP AAASGRENRQ LAGNSTRPMN
810 820 830 840 850
APEGARGPAS RRPGGKQRPE GSAKTQESVQ TSHPSQGNSS TSRKNSVGFF
860 870 880 890 900
VSAKNFSKPA VPPRLAPSAA KTRPGSALSS KSSGASTVGG CAYTPLAMAI
910 920 930 940 950
DAETLSSNSS SRGSSPQQQT PTNFPAVGSF VGSQPQGFLP FSMYPVYPFW
960 970 980 990 1000
PMGFPTPLSP PPVMGASLAG KEDAPSFFST PSFYPQAPGA SAFFRGEKGD
1010 1020 1030 1040 1050
GHKKKASGLV PNFAPFFPGA PGMYVHPREE SDAQAASRKK GKSQRKKGRE
1060 1070 1080 1090 1100
EEETKREEEA GRVNAEADGV SCEGQGEKEA NERTVEAPRA RIPQEQNARP
1110 1120 1130 1140 1150
NASVEKPPSR DKGADEDGWK VVKSRHEKRT HEPGNARGRG GRGRSDRARG

RGGRRSPE
Length:1,158
Mass (Da):123,048
Last modified:December 16, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF5D07CD2EC29A011
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
LN714497 Genomic DNA Translation: CEL74642.1
AAYL02000028 Genomic DNA Translation: ESS35507.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
ESS35507; ESS35507; TGVEG_255510

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN714497 Genomic DNA Translation: CEL74642.1
AAYL02000028 Genomic DNA Translation: ESS35507.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiB6KAP5

Genome annotation databases

EnsemblProtistsiESS35507; ESS35507; TGVEG_255510

Organism-specific databases

VEuPathDBiToxoDB:TGVEG_255510

Phylogenomic databases

eggNOGiKOG4177, Eukaryota
InParanoidiB6KAP5
OMAiKREWRAE

Family and domain databases

Gene3Di1.10.10.1440, 1 hit
1.25.40.20, 2 hits
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR019385, PHAX_RNA-binding_domain
IPR038092, PHAX_RNA-binding_sf
PfamiView protein in Pfam
PF12796, Ank_2, 2 hits
PF10258, RNA_GG_bind, 1 hit
SMARTiView protein in SMART
SM00248, ANK, 6 hits
SUPFAMiSSF48403, SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50088, ANK_REPEAT, 5 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB6KAP5_TOXGV
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B6KAP5
Secondary accession number(s): A0A0F7UWQ6, B9QC33, S8GKV1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 16, 2008
Last sequence update: December 16, 2008
Last modified: September 29, 2021
This is version 78 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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