UniProtKB - B6DU67 (B6DU67_HUMAN)
Protein
Submitted name:
Estrogen receptor alpha delta 3*,4,5,6,7*/775 hypothalamic isoform
Gene
ESR1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity Source: InterPro
- sequence-specific DNA binding Source: InterPro
- zinc ion binding Source: InterPro
Keywordsi
Molecular function | DNA-bindingARBA annotation, ReceptorImportedARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Estrogen receptor alpha delta 3*,4,5,6,7*/775 hypothalamic isoformImported |
Gene namesi | Name:ESR1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Nucleus
- nucleus Source: UniProtKB-KW
Keywords - Cellular componenti
NucleusARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 43 | Nuclear receptorInterPro annotationAdd BLAST | 43 |
Keywords - Domaini
Zinc-fingerARBA annotationFamily and domain databases
Gene3Di | 3.30.50.10, 1 hit |
InterProi | View protein in InterPro IPR001628, Znf_hrmn_rcpt IPR013088, Znf_NHR/GATA |
Pfami | View protein in Pfam PF00105, zf-C4, 1 hit |
SMARTi | View protein in SMART SM00399, ZnF_C4, 1 hit |
PROSITEi | View protein in PROSITE PS51030, NUCLEAR_REC_DBD_2, 1 hit |
i Sequence
Sequence statusi: Fragment.
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FJ169501 mRNA Translation: ACI04256.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FJ169501 mRNA Translation: ACI04256.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | B6DU67 |
Miscellaneous databases
ChiTaRSi | ESR1, human |
Family and domain databases
Gene3Di | 3.30.50.10, 1 hit |
InterProi | View protein in InterPro IPR001628, Znf_hrmn_rcpt IPR013088, Znf_NHR/GATA |
Pfami | View protein in Pfam PF00105, zf-C4, 1 hit |
SMARTi | View protein in SMART SM00399, ZnF_C4, 1 hit |
PROSITEi | View protein in PROSITE PS51030, NUCLEAR_REC_DBD_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B6DU67_HUMAN | |
Accessioni | B6DU67Primary (citable) accession number: B6DU67 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 25, 2008 |
Last sequence update: | November 25, 2008 | |
Last modified: | October 7, 2020 | |
This is version 78 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |