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Entry version 50 (11 Dec 2019)
Sequence version 1 (25 Nov 2008)
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Protein
Submitted name:

Acriflavin resistance protein

Gene

Gdia_1842

Organism
Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
GDIA272568:G1GTW-1880-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Acriflavin resistance proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Gdia_1842Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri272568 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGluconacetobacter
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000736 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei336 – 353HelicalSequence analysisAdd BLAST18
Transmembranei360 – 381HelicalSequence analysisAdd BLAST22
Transmembranei431 – 453HelicalSequence analysisAdd BLAST23
Transmembranei459 – 479HelicalSequence analysisAdd BLAST21
Transmembranei539 – 559HelicalSequence analysisAdd BLAST21
Transmembranei922 – 940HelicalSequence analysisAdd BLAST19
Transmembranei973 – 998HelicalSequence analysisAdd BLAST26
Transmembranei1023 – 1045HelicalSequence analysisAdd BLAST23
Transmembranei1051 – 1077HelicalSequence analysisAdd BLAST27

GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
272568.GDI1129

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. [View classification]SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
COG0841 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000158127

KEGG Orthology (KO)

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KOi
K07789

Database of Orthologous Groups

More...
OrthoDBi
145346at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.30.2090.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027463 AcrB_DN_DC_subdom
IPR001036 Acrflvin-R

The PANTHER Classification System

More...
PANTHERi
PTHR32063 PTHR32063, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00873 ACR_tran, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00702 ACRIFLAVINRP

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF82714 SSF82714, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B5ZLS5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNPCRPFILR PVATTLISLA LVIAGLFAYR ALPVGDLPNI SVPIIYVVAT
60 70 80 90 100
QPGSSPQQMA TSVTTPLERR LGQISGISAI ESDSTDSTAF ILLTFDDSRN
110 120 130 140 150
IDGAANDVQA ALRAATQDMP ATLQMVPQYW KANPADNPIM IMALTSDTRP
160 170 180 190 200
MADLYDVMKT HLQPMLSQIK GVGWIEITGS SAPAVRVEMN PYPLFKYGIG
210 220 230 240 250
FEDIRSALAS ANANTPKGFV DVGPQRYSIS TNDQARHAAD YRDLVVGYRG
260 270 280 290 300
SRPVRLTDVA SVVDGVEDER QTGYFNGHRA VMAIVRPQPG ANVIRVMDEI
310 320 330 340 350
KARTPAIIGA LPRGMTLTPA MDRSITIRAS LADTQLTLLI SVLLVVGVVL
360 370 380 390 400
VFLRAPRSTL IPAVTVPISL AGTLAAMYLL GFSLDTLSLM ALTIATGFVV
410 420 430 440 450
DDAIVVVENI ARHMEAGMDR RAASMLGAGE IAFTVLSITI ALVAVFLPLL
460 470 480 490 500
LMPGTPGKIF YEFAMTLAVT VGISLFLSIS LTPMMCSLLL DVAHGAPLPA
510 520 530 540 550
GASRTRRALR RLSDGIEATF EAILHTYVRS LDWALRHRWW VLSTLPLSLV
560 570 580 590 600
ATAGIIVLMP KNIIPKQDVA LIVGYFRGDE TGSFQKMDGK IRAVSAAMMA
610 620 630 640 650
DPDTESVAAF SGDTRVEGQA FAQMTDKHDR SDGPDEMIAR IHKRLEGLTG
660 670 680 690 700
VRLSLFSAGD VNGGGGRQQQ GAYRYVLRSD NAEDIYTWTP RLVQALQGSK
710 720 730 740 750
VMTDITTNLT NRAAASYVDI ARDTAARYLV TPQLISNALF DAYGQRSASN
760 770 780 790 800
ISTPIATYHV VMEVAPPYRQ SPDVMQAFRV STSGGSAGGG TVSNTVRVAL
810 820 830 840 850
SDPAATSQAS SLSQQSFRNA VANRLAGGAG ASSGSAVSSS IETMVPLPVV
860 870 880 890 900
SRIEQRPTSI SVSHRDGFVS GAVSFNLAKN RSLDEAAAEI RATMVRLHVP
910 920 930 940 950
ESVQGGFTGE AAQFQTAMIN ELLVFIAALA TMYVTLGILY ESYVHPLTIL
960 970 980 990 1000
STLPSAAVGA VLALWLTGQE FSLIAMIGVI LLVGIVKKNA ILMVDFALHA
1010 1020 1030 1040 1050
ERDGAMSPEE AIREACAKRF RPILMTTLAA AFGAVPLILS GGYGIELRRP
1060 1070 1080 1090 1100
LGIAVVGGLA MSQLLTLYTT PVVYLLLERI RSWVVRTASS RWRSHIGRAT

SLDRPTA
Length:1,107
Mass (Da):118,521
Last modified:November 25, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB31370D2498B7248
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP001189 Genomic DNA Translation: ACI51602.1

NCBI Reference Sequences

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RefSeqi
WP_012554001.1, NC_011365.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ACI51602; ACI51602; Gdia_1842

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
gdj:Gdia_1842

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001189 Genomic DNA Translation: ACI51602.1
RefSeqiWP_012554001.1, NC_011365.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi272568.GDI1129

Genome annotation databases

EnsemblBacteriaiACI51602; ACI51602; Gdia_1842
KEGGigdj:Gdia_1842

Phylogenomic databases

eggNOGiCOG0841 LUCA
HOGENOMiHOG000158127
KOiK07789
OrthoDBi145346at2

Enzyme and pathway databases

BioCyciGDIA272568:G1GTW-1880-MONOMER

Family and domain databases

Gene3Di3.30.2090.10, 3 hits
InterProiView protein in InterPro
IPR027463 AcrB_DN_DC_subdom
IPR001036 Acrflvin-R
PANTHERiPTHR32063 PTHR32063, 2 hits
PfamiView protein in Pfam
PF00873 ACR_tran, 2 hits
PRINTSiPR00702 ACRIFLAVINRP
SUPFAMiSSF82714 SSF82714, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB5ZLS5_GLUDA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B5ZLS5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: December 11, 2019
This is version 50 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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