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UniProtKB - B5XRR5 (B5XRR5_KLEP3)

Entry version 75 (02 Dec 2020)
Sequence version 1 (25 Nov 2008)
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Protein
Submitted name:

Type VI secretion ATPase, ClpV1 family

Gene

clpV

Organism
Klebsiella pneumoniae (strain 342)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperoneARBA annotation
LigandATP-bindingARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Type VI secretion ATPase, ClpV1 familyImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:clpVImported
Ordered Locus Names:KPK_3063Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiKlebsiella pneumoniae (strain 342)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri507522 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Klebsiella ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001734 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8 – 157Clp RInterPro annotationAdd BLAST150

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili447 – 467Sequence analysisAdd BLAST21
Coiled coili479 – 499Sequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ClpA/ClpB family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_005070_1_0_6

Identification of Orthologs from Complete Genome Data

More...OMAi		STALIEW

Database of Orthologous Groups

More...OrthoDBi		44062at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1780.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003593, AAA+_ATPase
IPR003959, ATPase_AAA_core
IPR017729, ATPase_T6SS_ClpV1
IPR019489, Clp_ATPase_C
IPR036628, Clp_N_dom_sf
IPR004176, Clp_R_dom
IPR001270, ClpA/B
IPR018368, ClpA/B_CS1
IPR041546, ClpA/ClpB_AAA_lid
IPR027417, P-loop_NTPase

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00004, AAA, 1 hit
PF07724, AAA_2, 1 hit
PF17871, AAA_lid_9, 1 hit
PF02861, Clp_N, 1 hit
PF10431, ClpB_D2-small, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00300, CLPPROTEASEA

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00382, AAA, 2 hits
SM01086, ClpB_D2-small, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540, SSF52540, 2 hits
SSF81923, SSF81923, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR03345, VI_ClpV1, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51903, CLP_R, 1 hit
PS00870, CLPAB_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B5XRR5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENPASLLRR LNPCCARAME GAASLCQTRA HAEILPEHWL LKLLEQGEGD 
        60         70         80         90        100
LTVLARRYEW DMDALWQDLL SWLDKQPRSV RHRPQLSDHT LRLMQEAWLI 
       110        120        130        140        150
ASLSGEAQIR SVHLLMALVE KQNLIQCDGL WPLLTLGQRQ LERLRPLLDA 
       160        170        180        190        200
QSDERPPAQQ EAALAQPHGG DVEFVGRPAG SELNADGLNP ALQNALDKFT 
       210        220        230        240        250
LDVTAKARDG QIDPVFGRDT EIRQMVDILS RRRKNNPILV GEPGVGKTAL 
       260        270        280        290        300
VEGLALRIAE GNVPDALKPV SVRTLDLGLL QAGAGVKGEF EQRLKNIIEA 
       310        320        330        340        350
VQQSPSPVLL FIDEAHTIIG AGNQAGGADA ANLLKPALAR GELRTIAATT 
       360        370        380        390        400
WSEYKQYFER DAALERRFQM VKVDEPDDET ACLMLRGLKS RYADHHGVHI 
       410        420        430        440        450
TDDAVRAAVT LSRRYLTGRQ LPDKAVDLLD TASARLRMSL DTVPEPLTRM 
       460        470        480        490        500
KAQLTALAME KQALLEDIAL GNSAHGERLA AIEQEETRLI LALDTLETQY 
       510        520        530        540        550
GQELQLTEAL LACRRDISRQ AEISDLQNAL IAVQLGNPLL GLDVDVRTVA 
       560        570        580        590        600
TVIADWTGVP LSSLMKDEQT ELLSLEESLG KRVVGQEAAL SAIARRLRAA 
       610        620        630        640        650
KTGLTPENGP QGVFLLVGPS GTGKTETALA LADALFGGEK ALITINLSEY 
       660        670        680        690        700
QEPHTVSQLK GSPPGYVGYG QGGILTEAVR KRPYSVVLLD EVEKAHRDVM 
       710        720        730        740        750
NLFYQVFDRG VMRDGEGREI DFRNTVILMT ANLGSDLLMQ LLDEQPQASE 
       760        770        780        790        800
SDLHELLRPV LRGHFQPALL ARFQTVIYRP LPAGALRAIV GMKLGQVSQR 
       810        820        830        840        850
LACHYGITTT LSESLFDALT EACLLPDTGA RNVDSLLNQQ ILPALSQQLL 
       860        870        880 
SHMAAGQKPR QVTLGYHEEE GVMMAFDEGT ISDE
Length:884
Mass (Da):96,987
Last modified:November 25, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2AB9DFBBF46A0D4E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CP000964 Genomic DNA Translation: ACI09800.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		ACI09800; ACI09800; KPK_3063

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		kpe:KPK_3063

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA Translation: ACI09800.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiACI09800; ACI09800; KPK_3063
KEGGikpe:KPK_3063

Phylogenomic databases

HOGENOMiCLU_005070_1_0_6
OMAiSTALIEW
OrthoDBi44062at2

Family and domain databases

Gene3Di1.10.1780.10, 1 hit
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR003959, ATPase_AAA_core
IPR017729, ATPase_T6SS_ClpV1
IPR019489, Clp_ATPase_C
IPR036628, Clp_N_dom_sf
IPR004176, Clp_R_dom
IPR001270, ClpA/B
IPR018368, ClpA/B_CS1
IPR041546, ClpA/ClpB_AAA_lid
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF00004, AAA, 1 hit
PF07724, AAA_2, 1 hit
PF17871, AAA_lid_9, 1 hit
PF02861, Clp_N, 1 hit
PF10431, ClpB_D2-small, 1 hit
PRINTSiPR00300, CLPPROTEASEA
SMARTiView protein in SMART
SM00382, AAA, 2 hits
SM01086, ClpB_D2-small, 1 hit
SUPFAMiSSF52540, SSF52540, 2 hits
SSF81923, SSF81923, 1 hit
TIGRFAMsiTIGR03345, VI_ClpV1, 1 hit
PROSITEiView protein in PROSITE
PS51903, CLP_R, 1 hit
PS00870, CLPAB_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB5XRR5_KLEP3
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B5XRR5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: December 2, 2020
This is version 75 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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