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Entry version 64 (02 Dec 2020)
Sequence version 1 (25 Nov 2008)
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Protein
Submitted name:

Type VI secretion system Vgr family protein

Gene

KPK_3062

Organism
Klebsiella pneumoniae (strain 342)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
KPNE507522:GI0B-3049-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Type VI secretion system Vgr family proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:KPK_3062Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiKlebsiella pneumoniae (strain 342)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri507522 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001734 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini404 – 471Phage_base_VInterPro annotationAdd BLAST68
Domaini489 – 585T6SS_VgrInterPro annotationAdd BLAST97
Domaini610 – 755DUF2345InterPro annotationAdd BLAST146

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the VgrG protein family.ARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004121_4_0_6

Identification of Orthologs from Complete Genome Data

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OMAi
YRVNMLF

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
2.40.50.230, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018769, DUF2345_Vgr_C
IPR006531, Gp5/Vgr_OB
IPR028244, T6SS_Rhs_Vgr_dom
IPR017847, T6SS_RhsGE_Vgr_subset
IPR006533, T6SS_Vgr_RhsGE
IPR037026, Vgr_OB-fold_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10106, DUF2345, 1 hit
PF04717, Phage_base_V, 1 hit
PF13296, T6SS_Vgr, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01646, vgr_GE, 1 hit
TIGR03361, VI_Rhs_Vgr, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B5XRR4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKSLLFSHNH HLLSVKGCEA GLDVLAFEGD EALSQPFRYR IEFTSADHAI
60 70 80 90 100
SKEMMLMKAA SLTLQAPVAQ GFGINVQQPV RVIQGVVTGF ERLSTSRDET
110 120 130 140 150
HYALTLQPRL ALLNRSHQNA IYQDQSVPQI VEKILRERHG LRGQDFLFSL
160 170 180 190 200
TKTYPRREQV MQYGEDDLRF ITRLLGEVGI WFRFTADTRL HIDVAEFCDS
210 220 230 240 250
QQGYEKGLTL PSVPPSGQQS AGVDAVWEMA CRHRVVEQQV STRDYNYREA
260 270 280 290 300
TADMSAQVDV TRGETTTFGE AYHWGDNYLT AGNAHDRHPA PESGAFYARL
310 320 330 340 350
RHERYLNGQT RMQATTSCPT LCPGQVLKVI GGEEVAGEFA EGVLVTAMHS
360 370 380 390 400
HARRDADFAV EFAGIPDSPD VGYRPEPGAR PVMAGTLPAR VTSTRENDTY
410 420 430 440 450
GHIDKHGRYR VNMLFDRARW ETGFESLWVR QSRPYAGDTY GLHLPLLAGT
460 470 480 490 500
EVAIGFEDGN PDRPYIAGVL HDSAHGDHVT IRNDKRNVLR TPANNKIRLD
510 520 530 540 550
DERGKEHIKV STEYGGKSQL NLGHLVDSDR RPRGEGFELR TDSRGAIRAQ
560 570 580 590 600
KGIFISADGQ AKAQGQVLAM EPAVSLLKGA VNQVTEWGSI TQTHHNVIPD
610 620 630 640 650
TGPLSALTTG TSDLKQPTLL MSAPQGIAAV TPETTLLHSG NGLYLQSLGE
660 670 680 690 700
VNITTAQRCS LNASQAISLL AQQEGMRLVS AKGPLEVESH GEILSLTALK
710 720 730 740 750
DITVQSTQGH LQLTAKNGIT LGCGGAYIRL TPQGEVQIHG PGVISLKGQH
760 770 780
DLQGPVSEAF PLPELPASVC KECLKKAQAL AQGFVPREA
Length:789
Mass (Da):86,487
Last modified:November 25, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i37482ABE3EE2D2AC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP000964 Genomic DNA Translation: ACI08501.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ACI08501; ACI08501; KPK_3062

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
kpe:KPK_3062

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA Translation: ACI08501.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiACI08501; ACI08501; KPK_3062
KEGGikpe:KPK_3062

Phylogenomic databases

HOGENOMiCLU_004121_4_0_6
OMAiYRVNMLF

Enzyme and pathway databases

BioCyciKPNE507522:GI0B-3049-MONOMER

Family and domain databases

Gene3Di2.40.50.230, 1 hit
InterProiView protein in InterPro
IPR018769, DUF2345_Vgr_C
IPR006531, Gp5/Vgr_OB
IPR028244, T6SS_Rhs_Vgr_dom
IPR017847, T6SS_RhsGE_Vgr_subset
IPR006533, T6SS_Vgr_RhsGE
IPR037026, Vgr_OB-fold_dom_sf
PfamiView protein in Pfam
PF10106, DUF2345, 1 hit
PF04717, Phage_base_V, 1 hit
PF13296, T6SS_Vgr, 1 hit
TIGRFAMsiTIGR01646, vgr_GE, 1 hit
TIGR03361, VI_Rhs_Vgr, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB5XRR4_KLEP3
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B5XRR4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: December 2, 2020
This is version 64 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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