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Protein

Ribosomal RNA small subunit methyltransferase F

Gene

rsmF

Organism
Klebsiella pneumoniae (strain 342)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(1407) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(1407) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei149S-adenosyl-L-methionineUniRule annotation1
Binding sitei176S-adenosyl-L-methionineUniRule annotation1
Binding sitei194S-adenosyl-L-methionineUniRule annotation1
Active sitei247NucleophileUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, RNA-binding, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase FUniRule annotation (EC:2.1.1.178UniRule annotation)
Alternative name(s):
16S rRNA m5C1407 methyltransferaseUniRule annotation
rRNA (cytosine-C(5)-)-methyltransferase RsmFUniRule annotation
Gene namesi
Name:rsmFUniRule annotation
Ordered Locus Names:KPK_1939
OrganismiKlebsiella pneumoniae (strain 342)
Taxonomic identifieri507522 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000001734 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001475711 – 477Ribosomal RNA small subunit methyltransferase FAdd BLAST477

Proteomic databases

PRIDEiB5XQ35

Structurei

3D structure databases

ProteinModelPortaliB5XQ35
SMRiB5XQ35
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni125 – 131S-adenosyl-L-methionine bindingUniRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000218115
KOiK11392
OMAiDPLFHAG

Family and domain databases

HAMAPiMF_01579 16SrRNA_methyltr_F, 1 hit
InterProiView protein in InterPro
IPR018314 Fmu/NOL1/Nop2p_CS
IPR031341 Methyltr_RsmF_N
IPR001678 MeTrfase_RsmB/NOP2
IPR027391 Nol1_Nop2_Fmu_2
IPR011023 Nop2p
IPR023267 RCMT
IPR023545 rRNA_ssu_MeTfrase_F
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF17125 Methyltr_RsmF_N, 1 hit
PF13636 Methyltranf_PUA, 1 hit
PRINTSiPR02008 RCMTFAMILY
SUPFAMiSSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00446 nop2p, 1 hit
PROSITEiView protein in PROSITE
PS01153 NOL1_NOP2_SUN, 1 hit
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

B5XQ35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAENTVYFPE AFLAQMRAAM PAHLSFDDFI AACQRPLRRS IRVNTLKISV
60 70 80 90 100
ADFLSLVAPY GWQLTPVPWC EEGFWIERDG DDALPLGSTA EHLSGLFYIQ
110 120 130 140 150
EASSMLPVAA LFADNPQPER VMDVAAAPGS KTTQIAARMG NAGGILANEF
160 170 180 190 200
SASRVKVLHA NISRCGISNV ALTHFDGRVF GAALPEAFDA ILLDAPCSGE
210 220 230 240 250
GVVRKDADAL KNWSPESNLD IAATQRELID SAFHALRPGG TLVYSTCTLN
260 270 280 290 300
REENQSVVQW LLSRYPQAVE ILPLGDLFSG AADALTAEGF LHVFPQIYDC
310 320 330 340 350
EGFFVARLRK TAAIDPLPAP GYKVGKFPFT PLKSREAAAV TAAANAVGLA
360 370 380 390 400
WDAGHTLWQR DKELWLFPQA MEPLFGQVRF SRIGVRLAEV HNKGYRWQHE
410 420 430 440 450
AVIAFAAPQR AFELTQEEAE EWYRGRDVYP QTAPQQDEAI VTFQGVPLGL
460 470
AKRVGSRLKN SYPRELVRDG KLFAGKV
Length:477
Mass (Da):52,392
Last modified:November 25, 2008 - v1
Checksum:iC65B0A7B9D42D7A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA Translation: ACI10246.1
RefSeqiWP_012541265.1, NC_011283.1

Genome annotation databases

EnsemblBacteriaiACI10246; ACI10246; KPK_1939
KEGGikpe:KPK_1939

Similar proteinsi

Entry informationi

Entry nameiRSMF_KLEP3
AccessioniPrimary (citable) accession number: B5XQ35
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 25, 2008
Last modified: May 23, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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