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Protein
Submitted name:

Tyrosine-protein phosphatase non-receptor type 6

Gene

PTN6

Organism
Salmo salar (Atlantic salmon)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei422SubstrateUniRule annotation1
Active sitei456Phosphocysteine intermediateUniRule annotation1
Binding sitei503SubstrateUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphataseSAAS annotation, ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Tyrosine-protein phosphatase non-receptor type 6Imported
Submitted name:
tyrosine-protein phosphatase non-receptor type 6 isoform X4Imported
Gene namesi
Name:PTN6Imported
Synonyms:ptn6Imported
OrganismiSalmo salar (Atlantic salmon)Imported
Taxonomic identifieri8030 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeSalmo
Proteomesi
  • UP000087266 Componenti: Genome assembly

Structurei

3D structure databases

ProteinModelPortaliB5X4B3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 100SH2InterPro annotationAdd BLAST97
Domaini110 – 213SH2InterPro annotationAdd BLAST104
Domaini248 – 518Tyrosine-protein phosphataseInterPro annotationAdd BLAST271
Domaini433 – 509TYR_PHOSPHATASE_2InterPro annotationAdd BLAST77

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG000223
KOiK05697

Family and domain databases

Gene3Di3.30.505.10, 2 hits
3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR012152 Tyr_Pase_non-rcpt_typ-6/11
IPR000387 TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00017 SH2, 2 hits
PF00102 Y_phosphatase, 1 hit
PIRSFiPIRSF000929 Tyr-Ptase_nr_6, 1 hit
PRINTSiPR00700 PRTYPHPHTASE
PR00401 SH2DOMAIN
SMARTiView protein in SMART
SM00194 PTPc, 1 hit
SM00404 PTPc_motif, 1 hit
SM00252 SH2, 2 hits
SUPFAMiSSF52799 SSF52799, 1 hit
SSF55550 SSF55550, 2 hits
PROSITEiView protein in PROSITE
PS50001 SH2, 2 hits
PS00383 TYR_PHOSPHATASE_1, 1 hit
PS50056 TYR_PHOSPHATASE_2, 1 hit
PS50055 TYR_PHOSPHATASE_PTP, 1 hit

Sequencei

Sequence statusi: Complete.

B5X4B3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRWFHRDIS GLDAESVLKS RGIHGSFLAR PSRKNQGDFS LSVRVGELVT
60 70 80 90 100
HIRIQNTGDF YDLYGGEKFA TLSELVEYYT AENGILQDKD GTIIELKYPF
110 120 130 140 150
NCSDPTTERW YHGHLSGPNA EKLLWERDEP GTFLVRESLS KPGDFVLSVL
160 170 180 190 200
TEEKSKASSG GRRVSHIKIM CQNDRYTVGG TEMFDTLADL MEHYKRKGIE
210 220 230 240 250
EMSGTWVHLK QPYFSTRVNA ADIDSRVRLL DQTAERENEG DKKSKAGFWE
260 270 280 290 300
EFDALQKQET KVKKSREEGM RPENKSKNRY KNILPFDETR VILSSGDPNI
310 320 330 340 350
IGSDYINANY VTNKLQESGD QKVYIACQGC LATTVNDFWQ MVWQEKTRVI
360 370 380 390 400
VMTTREVEKG RNKCVPYWPE MQGSKEVGPY VVTCVSERDA TDYKVRVMEI
410 420 430 440 450
SPLDQSDSVR TIWHYQYLSW PDHGVPEEPG GVLSFLSQVN LKQAEFTNAG
460 470 480 490 500
PMIIHCSAGI GRTGTIVVID MIIKTIDTKG LDCDIDIQKS IQMVRDQRSG
510 520 530 540 550
MVQTEAQYKF IYLAVSEYIE ASKTYNKGAE TEYGNLQFKH QPASRKVSKN
560 570 580
KEQELYENLA KGKKDVKKQK SEEKKSGSVR KR
Length:582
Mass (Da):66,427
Last modified:November 25, 2008 - v1
Checksum:iA494CFDB4C0EBEA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT045882 mRNA Translation: ACI34144.1
RefSeqiNP_001133922.1, NM_001140450.1
XP_014007788.1, XM_014152313.1
XP_014007795.1, XM_014152320.1
XP_014007805.1, XM_014152330.1
XP_014007810.1, XM_014152335.1
UniGeneiSsa.5973

Genome annotation databases

GeneIDi100195421
KEGGisasa:100195421

Similar proteinsi

Entry informationi

Entry nameiB5X4B3_SALSA
AccessioniPrimary (citable) accession number: B5X4B3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: May 23, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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