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UniProtKB - B5X0T0 (B5X0T0_SALSA)

Entry version 58 (10 Feb 2021)
Sequence version 1 (25 Nov 2008)
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Protein

Fructose-bisphosphate aldolase

Gene

ALDOC

Organism
Salmo salar (Atlantic salmon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: glycolysis

This protein is involved in step 4 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationARBA annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. Hexokinase (LOC106589825), Hexokinase (LOC106564733), Hexokinase (LOC106589825), Hexokinase (LOC106612430), Phosphotransferase (LOC106585167), Hexokinase (LOC106585103), Hexokinase (LOC106587516), Phosphotransferase (LOC106580495), Hexokinase (LOC106580495), Phosphotransferase (LOC106580581), Phosphotransferase (LOC106585167), Phosphotransferase (LOC106568009), Phosphotransferase (LOC106585167), Hexokinase (LOC106585103), Phosphotransferase (LOC106580581), Phosphotransferase (LOC106585167), Hexokinase (LOC106612435)
  2. Glucose-6-phosphate isomerase (LOC106587569), Glucose-6-phosphate isomerase (G6PI)
  3. ATP-dependent 6-phosphofructokinase, liver type-like (LOC106593347), ATP-dependent 6-phosphofructokinase (LOC106568830), ATP-dependent 6-phosphofructokinase (k6pp), ATP-dependent 6-phosphofructokinase, muscle type-like (LOC106572730), ATP-dependent 6-phosphofructokinase (LOC106568830), ATP-dependent 6-phosphofructokinase (k6pp), ATP-dependent 6-phosphofructokinase (LOC106578535), ATP-dependent 6-phosphofructokinase (LOC106582566), ATP-dependent 6-phosphofructokinase (LOC106583067), ATP-dependent 6-phosphofructokinase (K6PP), ATP-dependent 6-phosphofructokinase (LOC106565515), ATP-dependent 6-phosphofructokinase (LOC106578535), ATP-dependent 6-phosphofructokinase (k6pp), ATP-dependent 6-phosphofructokinase (LOC106578535), ATP-dependent 6-phosphofructokinase (LOC106572792), ATP-dependent 6-phosphofructokinase (LOC106566997), ATP-dependent 6-phosphofructokinase (LOC106578535), ATP-dependent 6-phosphofructokinase (LOC106578535), ATP-dependent 6-phosphofructokinase (LOC106578535), ATP-dependent 6-phosphofructokinase (LOC106578535)
  4. Fructose-bisphosphate aldolase (ALDOB), Fructose-bisphosphate aldolase (LOC106612788), Fructose-bisphosphate aldolase (ALDOB), Fructose-bisphosphate aldolase A, Fructose-bisphosphate aldolase (aldA), Fructose-bisphosphate aldolase (aldoc), Fructose-bisphosphate aldolase (LOC100194624), Fructose-bisphosphate aldolase (ALF1), Fructose-bisphosphate aldolase (ALDOC), Fructose-bisphosphate aldolase, Fructose-bisphosphate aldolase (LOC100194623), Fructose-bisphosphate aldolase (LOC106604855), Fructose-bisphosphate aldolase (ALDOA)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLyaseUniRule annotation
Biological processGlycolysisUniRule annotation
LigandSchiff baseARBA annotation

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00109;UER00183

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Fructose-bisphosphate aldolaseUniRule annotationARBA annotation (EC:4.1.2.13UniRule annotationARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ALDOCImported
Synonyms:aldocImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSalmo salar (Atlantic salmon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8030 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Protacanthopterygii › Salmoniformes › Salmonidae › Salmoninae › Salmo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000087266 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Protein family/group databases

Allergome; a platform for allergen knowledge

More...Allergomei		10151, Sal s 3

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the class I fructose-bisphosphate aldolase family.UniRule annotationARBA annotation

Phylogenomic databases

Database of Orthologous Groups

More...OrthoDBi		799973at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.20.20.70, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029768, Aldolase_I_AS
IPR013785, Aldolase_TIM
IPR000741, FBA_I

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00274, Glycolytic, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00158, ALDOLASE_CLASS_I, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B5X0T0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTHQFPALSS GQKQELQEIA LRIVTPGKGI LAADESVGSM AKRLNQIGVE 
        60         70         80         90        100
NTEENRRQYR QILFRADDRI NSCIGGVIFF HETLYQHADD GTPFVKMIKD 
       110        120        130        140        150
RGITVGIKVD KGVVPLAGTN AESTTQGLDG LSERCIQYKK DGANFAKWRC 
       160        170        180        190        200
VFKISETTPS KLSIEENANV LARYSSICQQ HGIVPIVEPE ILSDGDHDLR 
       210        220        230        240        250
RCQYVTEKVL AALYKAMSDH HVYLEGTLLK PNMATPGHSC PTKYSAEEVA 
       260        270        280        290        300
MATVTALRRT VPPAVTGVTF LSGGQSEEEA SVHLNAINNC SLVKPWALTF 
       310        320        330        340        350
SYGRALQVSA LKTWRGHKEN ENAATEQFIK RAEVNGLACQ GKYTGGGDSE 
       360 
SDQIYVANHA Y
Length:361
Mass (Da):39,634
Last modified:November 25, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i56FE5B70A8C533F2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BT044649 mRNA Translation: ACI32911.1

NCBI Reference Sequences

More...RefSeqi		NP_001135182.1, NM_001141710.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSSSAT00000071267; ENSSSAP00000044518; ENSSSAG00000046596

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100196688

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		sasa:100196688

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT044649 mRNA Translation: ACI32911.1
RefSeqiNP_001135182.1, NM_001141710.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein family/group databases

Allergomei10151, Sal s 3

Genome annotation databases

EnsembliENSSSAT00000071267; ENSSSAP00000044518; ENSSSAG00000046596
GeneIDi100196688
KEGGisasa:100196688

Phylogenomic databases

OrthoDBi799973at2759

Enzyme and pathway databases

UniPathwayiUPA00109;UER00183

Family and domain databases

Gene3Di3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR029768, Aldolase_I_AS
IPR013785, Aldolase_TIM
IPR000741, FBA_I
PfamiView protein in Pfam
PF00274, Glycolytic, 1 hit
PROSITEiView protein in PROSITE
PS00158, ALDOLASE_CLASS_I, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB5X0T0_SALSA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B5X0T0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: February 10, 2021
This is version 58 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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