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Entry version 52 (08 May 2019)
Sequence version 1 (25 Nov 2008)
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Protein
Submitted name:

TPR repeat-containing protein

Gene

AmaxDRAFT_0056

Organism
Arthrospira maxima CS-328
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
TPR repeat-containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:AmaxDRAFT_0056Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArthrospira maxima CS-328Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri513049 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesMicrocoleaceaeArthrospira
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000004061 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 604TPR_REGIONInterPro annotationAdd BLAST604
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati6 – 39TPRPROSITE-ProRule annotationAdd BLAST34
Repeati40 – 73TPRPROSITE-ProRule annotationAdd BLAST34
Repeati74 – 107TPRPROSITE-ProRule annotationAdd BLAST34
Repeati108 – 141TPRPROSITE-ProRule annotationAdd BLAST34
Repeati142 – 174TPRPROSITE-ProRule annotationAdd BLAST33
Repeati175 – 208TPRPROSITE-ProRule annotationAdd BLAST34
Repeati298 – 331TPRPROSITE-ProRule annotationAdd BLAST34
Repeati332 – 365TPRPROSITE-ProRule annotationAdd BLAST34
Repeati366 – 399TPRPROSITE-ProRule annotationAdd BLAST34
Repeati400 – 433TPRPROSITE-ProRule annotationAdd BLAST34
Repeati436 – 469TPRPROSITE-ProRule annotationAdd BLAST34
Repeati470 – 503TPRPROSITE-ProRule annotationAdd BLAST34
Repeati504 – 537TPRPROSITE-ProRule annotationAdd BLAST34
Repeati538 – 571TPRPROSITE-ProRule annotationAdd BLAST34
Repeati572 – 604TPRPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili476 – 499Sequence analysisAdd BLAST24

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105EN5 Bacteria
COG0457 LUCA
COG3914 LUCA

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 5 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037919 OGT
IPR029489 OGT/SEC/SPY_C
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

The PANTHER Classification System

More...
PANTHERi
PTHR44366 PTHR44366, 5 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13844 Glyco_transf_41, 2 hits
PF13181 TPR_8, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00028 TPR, 15 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50005 TPR, 15 hits
PS50293 TPR_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B5VU12-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNSEQIKVYC CQGQVFFSRG DYPASIEAYM KALELDIKNA DVYIMLAESY
60 70 80 90 100
IYNQEIDAAI SALEKALKLQ PDLAGAYMRV GNALQMCNCL DLAIWAYTQG
110 120 130 140 150
LEIEPNYSIA YSNLGGVYYQ QQRWHEAINC YQKCLGIDPD LAIVHWMLGN
160 170 180 190 200
ALIKSGDMAG AITCYQRAIN LQDRPDFYRK LAEALEKNGQ INEAIANYKT
210 220 230 240 250
ALKLDANNSD IIGKIAELKS RLETPVSGSI SESMNFIEDA TDSFDEQGVD
260 270 280 290 300
FSGQVLEGEL HYQEETQESE DLVTPPTEQL LIQADAKFWA QKPINPRVLS
310 320 330 340 350
LQKQAELYLS QGKLEETVAT CQQILKLDPN FLFVYVVLGN ALHFQGKISS
360 370 380 390 400
AIRAYNQALE IHPDFAEVHA NLATMYLQNG QVNEAIAAYQ KSIEIKPDLA
410 420 430 440 450
AVHWNLGRVY QQLGNTEAAI NSWKIALELK PDLVEADFHF ELGNILARRG
460 470 480 490 500
EYEPAIASYQ RAISRKPNWA EPYANIGCLR VQQDRLKEAL DQLQKAIALS
510 520 530 540 550
PKMPELYLHT ARIFTKLRRH QDAINHYQKV IELQPNFPDA YANLANMQAI
560 570 580 590 600
LGQLPEAIAN YQKTLQLKPE WAEVYCRLAH IQKQKEPKEA VANLEKALEL
610 620 630 640 650
KPDFAEAYQQ LCDLLSHSTN LGKARKVADR YWENCGKTLP VLCAIAYIFS
660 670 680 690 700
YTQSGACEQA LAKLEHLETI CNNSMETLTE IEIRLIYEII LFTVPHLRDN
710 720 730 740 750
LEGNAQFYQI ICQSYYQEPI ATPPSIYAEP RSPLKIGFLS KHFRRHSVGW
760 770 780 790 800
CAEGVIKEMS AITPHINLYI SGILHPDEVT ARYEQTVAKC YWPKSYPNGF
810 820 830 840 850
ASAEELSQEI RSDRIDVLVD LDSVTIPVNV QVLHKSPAPV CVTWLGFDAP
860 870 880 890 900
YLTSNHYLIC DQHTHPPGIE KHYLERLVRL PDTAVAIAGL PTRPVDRNMV
910 920 930 940 950
RQQLNIPPNA VAYLCVAPGR KTNGEMIKAQ VNILRSVPNS VLIRKGQGDA
960 970 980 990 1000
QLLREMYNQA CEDLGVDINR LIFLGLTKTE EEHRAIYKVA DVMLDSYPYN
1010 1020 1030 1040 1050
GGTHNLEALW SELPVVTRSG RQYLSRMGYA FLKSVNLDIG VAWSWEEYTQ
1060 1070 1080 1090 1100
LGIEFGQNAT LRQQISNHLA RVKQPETLAP LWNPKQLAIQ MYRTFEQLRR

VTN
Length:1,103
Mass (Da):124,862
Last modified:November 25, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF2C971E1115A5E8A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
ABYK01000001 Genomic DNA Translation: EDZ97028.1

NCBI Reference Sequences

More...
RefSeqi
WP_006667893.1, NZ_ABYK01000001.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
EDZ97028; EDZ97028; AmaxDRAFT_0056

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABYK01000001 Genomic DNA Translation: EDZ97028.1
RefSeqiWP_006667893.1, NZ_ABYK01000001.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiEDZ97028; EDZ97028; AmaxDRAFT_0056

Phylogenomic databases

eggNOGiENOG4105EN5 Bacteria
COG0457 LUCA
COG3914 LUCA

Family and domain databases

Gene3Di1.25.40.10, 5 hits
InterProiView protein in InterPro
IPR037919 OGT
IPR029489 OGT/SEC/SPY_C
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PANTHERiPTHR44366 PTHR44366, 5 hits
PfamiView protein in Pfam
PF13844 Glyco_transf_41, 2 hits
PF13181 TPR_8, 2 hits
SMARTiView protein in SMART
SM00028 TPR, 15 hits
SUPFAMiSSF48452 SSF48452, 3 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 15 hits
PS50293 TPR_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB5VU12_ARTMA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B5VU12
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: May 8, 2019
This is version 52 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health

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