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Protein
Submitted name:

Maltase-glucoamylase

Gene

Mgam

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionGlycosidaseImported, Hydrolase

Enzyme and pathway databases

ReactomeiR-MMU-189085 Digestion of dietary carbohydrate
R-MMU-6798695 Neutrophil degranulation

Protein family/group databases

CAZyiGH31 Glycoside Hydrolase Family 31

Names & Taxonomyi

Protein namesi
Submitted name:
Maltase-glucoamylaseImported (EC:3.2.1.20Imported)
Gene namesi
Name:MgamImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1203495 Mgam

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 35HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi87 ↔ 104PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000068587 Expressed in 83 organ(s), highest expression level in intestine

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000071466

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 108P-typeInterPro annotationAdd BLAST46
Domaini924 – 974P-typeInterPro annotationAdd BLAST51

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1065 Eukaryota
COG1501 LUCA
GeneTreeiENSGT00760000119229
HOVERGENiHBG080721
KOiK12047
OrthoDBiEOG091G01E3
TreeFamiTF314577

Family and domain databases

CDDicd00111 Trefoil, 2 hits
Gene3Di2.60.40.1180, 4 hits
InterProiView protein in InterPro
IPR031727 Gal_mutarotase_N
IPR011013 Gal_mutarotase_sf_dom
IPR000322 Glyco_hydro_31
IPR030458 Glyco_hydro_31_AS
IPR030459 Glyco_hydro_31_CS
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR000519 P_trefoil_dom
PfamiView protein in Pfam
PF01055 Glyco_hydro_31, 2 hits
PF16863 NtCtMGAM_N, 2 hits
PF00088 Trefoil, 2 hits
SMARTiView protein in SMART
SM00018 PD, 2 hits
SUPFAMiSSF51445 SSF51445, 2 hits
SSF74650 SSF74650, 2 hits
PROSITEiView protein in PROSITE
PS00129 GLYCOSYL_HYDROL_F31_1, 2 hits
PS00707 GLYCOSYL_HYDROL_F31_2, 1 hit
PS51448 P_TREFOIL_2, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

B5THE2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGRRFKKFS KLELVLIVLL LVLFIIAVVL IVLLANSTPE NAIGAETTGT
60 70 80 90 100
PDTTVTRTTL NSPNCPVLSE LERINCIPDQ SSNKGTCDER GCCWDPQGSI
110 120 130 140 150
SVPCYYSRNH GYKMESDVVN TNAGFTATLK NLPSAPVFGN SIENILLTAE
160 170 180 190 200
YQTSNRFHFK LTDQTKKRYE VPHEHVQPFS GNAPSSLNYK VEVSKEPFSI
210 220 230 240 250
KVTRKSNNRV LFDSSIGPLL FSDQFLQFST HLPSANVYGL GEHVHQQYRH
260 270 280 290 300
NMNWKTWPMF SRDTTPNEDG TNLYGVQTFF LCLEDNSGLS FGVFLMNSNA
310 320 330 340 350
MEVTLQPTPA ITYRTTGGIL DFYVFLGNTP EQVVQEYLEL IGRPALPSYW
360 370 380 390 400
TLGFQLSRYD YKSLDNMKAV VERNRAAQLP YDVQHADIDY MDQKKDFTYD
410 420 430 440 450
PVNFKGFPEF VKELHNNGQK LVIILDPAIS NNSFSSNPYG PYDRGSAMKI
460 470 480 490 500
WVNSSDGISP VIGKVWPGTT VFPDYTSPNC AVWWTKEFEL FHKEVEFDGI
510 520 530 540 550
WIDMNEVSNF IDGSFSGCSQ NNLNYPPFTP KVLDGYLFSK TLCMDAVQHW
560 570 580 590 600
GKQYDVHNLY GYSMAIATAK AVKDVFPDKR SFIITRSTFA GSGKFAAHWL
610 620 630 640 650
GDNTATWKDL QWSIPGMLEF NLFGIPMVGA DICGFAQDTY EELCRRWMQL
660 670 680 690 700
GAFYPFSRNH NGQGYKDQDP ASFGNNSLLL NSSRHYLNIR YTLLPYLYTL
710 720 730 740 750
FYRAHSRGDT VARPLLHEFY DDNNTWGIDR QFLWGPGLLI TPVLDQGAEK
760 770 780 790 800
VKAYVPNATW YDYETGEELG WRKQSIEMQL PGDKIGLHLR GGYIFPTQQP
810 820 830 840 850
ATTTEASRKN PLGLIVALDE NKEARGELFW DDGESKDTVA QNIYLFSEFS
860 870 880 890 900
VTQNHLDVTI SSPNYKDPNN LEFQEIKIFG TREFRNVRVK QNGNLLQMSP
910 920 930 940 950
QVTYNPNLKV ATITNIHLRL GEAYTVEWDF FTREEERIDC YPDEHGASEA
960 970 980 990 1000
NCSARGCIWE ASNTTRGPPC YFAHELYSVS NVQYDSHGAT ADISLKASTY
1010 1020 1030 1040 1050
SNAFPSTPVN KLKLQVTYHK NEMLQFKIYD PNHSRYEVPV PLNIPSAPLS
1060 1070 1080 1090 1100
TPEGRLYDVL IKENPFGIQI RRKTTGTVIW DSQLLGFTFN DMFIRISTRL
1110 1120 1130 1140 1150
PSTYIYGFGE TEHTTFKIDM NWHTWGMFSR DEPPGYKKNS YGVHPYYMGL
1160 1170 1180 1190 1200
EEDGNAHGVL LMNSNAMDVT FQPMPALTYR TIGGILDFYV FLGPTPEIVT
1210 1220 1230 1240 1250
QQYTELIGRP VMVPYWSLGF QLCRYGYEND TEIANLYDEM VAKQIPYDVQ
1260 1270 1280 1290 1300
YSDIDYMERQ LDFKLSPKFS GFPALINRMK ANGMRVILIL DPAISGNETE
1310 1320 1330 1340 1350
PYPAFTRGVE NDVFIRYPNN GSIVWGKVWP DYPNITVDPS LGWDHQVEQY
1360 1370 1380 1390 1400
RAYVAFPDFF RNSTATWWKK EIKELHSNTQ DPAKSLKFDG LWIDMNEPSS
1410 1420 1430 1440 1450
FVNGAVPSGC SDATLNHPPY MPYLEARDRG LSSKTLCMES EQILPDGSRV
1460 1470 1480 1490 1500
RHYDVHNLYG WSQTRPTYEA VQEVTGERGI VITRSTFPSS GRWGGHWLGD
1510 1520 1530 1540 1550
NTAAWDQLGK SIIGMMDFSL FGISYTGSDI CGFFQDAEYE MCVRWMQLGA
1560 1570 1580 1590 1600
FYPFSRNHNT IGTRRQDPVS WNKTFEDISR SVLETRYTLL PYLYTLMYKA
1610 1620 1630 1640 1650
HTEGSTVVRP LLHEFVSDRE TWNIDKQFLL GPAFLVSPVL EPNARKVEAY
1660 1670 1680 1690 1700
FPRARWYDYY KGVDINATGE WKTLEAPLEY INLHIRGGYI LPWQEPAMNT
1710 1720 1730 1740 1750
HLSRQKFMGL RAALNAEGRA EGWLFWDDGK RINTDQYYLA RFSVNQTTLL
1760 1770 1780 1790 1800
THEKFNNYLT GTAPLYLGYI DIWGLSSSSI TNVSISWNTN NEEVFANYNS
1810 1820
TTKILSVNMT DKKISLHTFN SLTWSSS
Length:1,827
Mass (Da):208,549
Last modified:November 4, 2008 - v1
Checksum:i00FD29494C846ACE
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6XK23Q6XK23_MOUSE
Maltase-glucoamylase
Mgam
316Annotation score:
A0A0J9YVJ0A0A0J9YVJ0_MOUSE
Maltase-glucoamylase
Mgam
986Annotation score:
A0A0J9YVE6A0A0J9YVE6_MOUSE
Maltase-glucoamylase
Mgam
1,200Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC153378 Genomic DNA No translation available.
AC158685 Genomic DNA No translation available.
EU937529 mRNA Translation: ACH86011.1
RefSeqiNP_001164474.1, NM_001171003.1
UniGeneiMm.33401

Genome annotation databases

EnsembliENSMUST00000071535; ENSMUSP00000071466; ENSMUSG00000068587
ENSMUST00000201148; ENSMUSP00000143946; ENSMUSG00000068587
GeneIDi232714
KEGGimmu:232714
UCSCiuc009bnf.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC153378 Genomic DNA No translation available.
AC158685 Genomic DNA No translation available.
EU937529 mRNA Translation: ACH86011.1
RefSeqiNP_001164474.1, NM_001171003.1
UniGeneiMm.33401

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000071466

Protein family/group databases

CAZyiGH31 Glycoside Hydrolase Family 31

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000071535; ENSMUSP00000071466; ENSMUSG00000068587
ENSMUST00000201148; ENSMUSP00000143946; ENSMUSG00000068587
GeneIDi232714
KEGGimmu:232714
UCSCiuc009bnf.2 mouse

Organism-specific databases

CTDi8972
MGIiMGI:1203495 Mgam

Phylogenomic databases

eggNOGiKOG1065 Eukaryota
COG1501 LUCA
GeneTreeiENSGT00760000119229
HOVERGENiHBG080721
KOiK12047
OrthoDBiEOG091G01E3
TreeFamiTF314577

Enzyme and pathway databases

ReactomeiR-MMU-189085 Digestion of dietary carbohydrate
R-MMU-6798695 Neutrophil degranulation

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000068587 Expressed in 83 organ(s), highest expression level in intestine

Family and domain databases

CDDicd00111 Trefoil, 2 hits
Gene3Di2.60.40.1180, 4 hits
InterProiView protein in InterPro
IPR031727 Gal_mutarotase_N
IPR011013 Gal_mutarotase_sf_dom
IPR000322 Glyco_hydro_31
IPR030458 Glyco_hydro_31_AS
IPR030459 Glyco_hydro_31_CS
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR000519 P_trefoil_dom
PfamiView protein in Pfam
PF01055 Glyco_hydro_31, 2 hits
PF16863 NtCtMGAM_N, 2 hits
PF00088 Trefoil, 2 hits
SMARTiView protein in SMART
SM00018 PD, 2 hits
SUPFAMiSSF51445 SSF51445, 2 hits
SSF74650 SSF74650, 2 hits
PROSITEiView protein in PROSITE
PS00129 GLYCOSYL_HYDROL_F31_1, 2 hits
PS00707 GLYCOSYL_HYDROL_F31_2, 1 hit
PS51448 P_TREFOIL_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiB5THE2_MOUSE
AccessioniPrimary (citable) accession number: B5THE2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 4, 2008
Last sequence update: November 4, 2008
Last modified: November 7, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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