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Protein
Submitted name:

NAD-dependent protein deacetylase sirtuin-2

Gene

SIRT2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
NAD-dependent protein deacetylase sirtuin-2Imported
Gene namesi
Name:SIRT2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000068903.19
HGNCiHGNC:10886 SIRT2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000068903

PTM / Processingi

Proteomic databases

MaxQBiB5MCS1
PeptideAtlasiB5MCS1
PRIDEiB5MCS1

Expressioni

Gene expression databases

BgeeiENSG00000068903
ExpressionAtlasiB5MCS1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB5MCS1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 169Deacetylase sirtuin-typeInterPro annotationAdd BLAST142

Phylogenomic databases

eggNOGiKOG2682 Eukaryota
COG0846 LUCA
GeneTreeiENSGT00870000136486
HOGENOMiHOG000085952

Family and domain databases

InterProiView protein in InterPro
IPR029035 DHS-like_NAD/FAD-binding_dom
IPR003000 Sirtuin
IPR026590 Ssirtuin_cat_dom
PfamiView protein in Pfam
PF02146 SIR2, 1 hit
SUPFAMiSSF52467 SSF52467, 1 hit
PROSITEiView protein in PROSITE
PS50305 SIRTUIN, 1 hit

Sequencei

Sequence statusi: Fragment.

B5MCS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFLRNLFSQ TLSLGSQKER LLDELTLEGV ARYMQSERCR RVICLVGAGI
60 70 80 90 100
STSAGIPDFR SPSTGLYDNL EKYHLPYPEA IFEISYFKKH PEPFFALAKE
110 120 130 140 150
LYPGQFKPTI CHYFMRLLKD KGLLLRCYTQ NIDTLERIAG LEQEDLVEAH
160
GTFYTSHCVS ASCRHEYPL
Length:169
Mass (Da):19,467
Last modified:October 14, 2008 - v1
Checksum:i924D7C0175CB6375
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei169Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011455 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000407552; ENSP00000385146; ENSG00000068903
UCSCiuc060yhc.1 human

Similar proteinsi

Entry informationi

Entry nameiB5MCS1_HUMAN
AccessioniPrimary (citable) accession number: B5MCS1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 14, 2008
Last modified: March 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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