UniProtKB - B5LBL2 (B5LBL2_STREE)
Protein
Prephenate dehydratase
Gene
pheA
Organism
Streptococcus pneumoniae
Status
Functioni
Catalytic activityi
- EC:4.2.1.51UniRule annotationARBA annotation
: L-phenylalanine biosynthesis Pathwayi
This protein is involved in step 1 of the subpathway that synthesizes phenylpyruvate from prephenate.UniRule annotationARBA annotationProteins known to be involved in this subpathway in this organism are:
- Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Shikimate kinase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA2), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA), Prephenate dehydratase (pheA)
View all proteins of this organism that are known to be involved in the subpathway that synthesizes phenylpyruvate from prephenate, the pathway L-phenylalanine biosynthesis and in Amino-acid biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 171 | Essential for prephenate dehydratase activityUniRule annotation | 1 |
GO - Molecular functioni
- chorismate mutase activity Source: InterPro
- prephenate dehydratase activity Source: UniProtKB-UniRule
GO - Biological processi
- L-phenylalanine biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | LyaseUniRule annotationARBA annotation |
Biological process | Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Phenylalanine biosynthesisUniRule annotationARBA annotation |
Enzyme and pathway databases
UniPathwayi | UPA00121;UER00345 |
Names & Taxonomyi
Protein namesi | Recommended name: Prephenate dehydrataseUniRule annotationARBA annotation (EC:4.2.1.51UniRule annotationARBA annotation)Short name: PDTUniRule annotation |
Gene namesi | Name:pheAUniRule annotationImported |
Organismi | Streptococcus pneumoniaeImported |
Taxonomic identifieri | 1313 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 178 | Prephenate dehydrataseInterPro annotationAdd BLAST | 177 | |
Domaini | 194 – 270 | ACTInterPro annotationAdd BLAST | 77 |
Family and domain databases
InterProi | View protein in InterPro IPR002912, ACT_dom IPR008242, Chor_mutase/pphenate_deHydtase IPR001086, Preph_deHydtase IPR018528, Preph_deHydtase_CS |
Pfami | View protein in Pfam PF00800, PDT, 1 hit |
PIRSFi | PIRSF001500, Chor_mut_pdt_Ppr, 1 hit |
PROSITEi | View protein in PROSITE PS51671, ACT, 1 hit PS00858, PREPHENATE_DEHYDR_2, 1 hit PS51171, PREPHENATE_DEHYDR_3, 1 hit |
i Sequence
Sequence statusi: Complete.
B5LBL2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKIAYLGPKG SFSHHVVQTA FPKEELHAFA NITDVIKAYE QGLVDYSVVP
60 70 80 90 100
VENSIEGSVH ESLDYLFHQA RIQAVAEIVQ PIHQQLMAVP GHTKIEKIFS
110 120 130 140 150
HPQALAQGKK FIDEHYPEAQ IEVTASTAYA ARFISEHPDQ PYAAIAPKSS
160 170 180 190 200
AEEYGLELIA EDIQEMEANF TRFWVLGAEI PKIPLNSQAE KMSLALTLPD
210 220 230 240 250
NLPGALYKAL STFAWRGIDL TKIESRPLKT ALGEYFFIID VDYSDKELVH
260 270 280
FARQELEAIG IQHKILGIYP IFTITDIEKE SQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EU675999 Genomic DNA Translation: ACH47975.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EU675999 Genomic DNA Translation: ACH47975.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Enzyme and pathway databases
UniPathwayi | UPA00121;UER00345 |
Family and domain databases
InterProi | View protein in InterPro IPR002912, ACT_dom IPR008242, Chor_mutase/pphenate_deHydtase IPR001086, Preph_deHydtase IPR018528, Preph_deHydtase_CS |
Pfami | View protein in Pfam PF00800, PDT, 1 hit |
PIRSFi | PIRSF001500, Chor_mut_pdt_Ppr, 1 hit |
PROSITEi | View protein in PROSITE PS51671, ACT, 1 hit PS00858, PREPHENATE_DEHYDR_2, 1 hit PS51171, PREPHENATE_DEHYDR_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B5LBL2_STREE | |
Accessioni | B5LBL2Primary (citable) accession number: B5LBL2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 14, 2008 |
Last sequence update: | October 14, 2008 | |
Last modified: | August 12, 2020 | |
This is version 31 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |