Neurod6

Functionⁱ

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro
RNA polymerase II proximal promoter sequence-specific DNA binding Source: Ensembl
transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cell differentiation Source: UniProtKB-KW
dentate gyrus development Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Developmental proteinUniRule annotation, DNA-bindingUniRule annotation
Biological process	DifferentiationUniRule annotation, NeurogenesisUniRule annotation, Transcription, Transcription regulationUniRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Neurogenic differentiation factorUniRule annotation
Gene namesⁱ	Name:Neurod6Imported ORF Names:rCG_52313Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 4

Organism-specific databases

Rat genome database More...RGDⁱ	1562793 Neurod6

RGDⁱ

1562793 Neurod6

Keywords - Cellular componentⁱ

NucleusUniRule annotation

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000026055 Expressed in 1 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000026055 Expressed in 1 organ(s), highest expression level in brain

Interactionⁱ

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000016182

STRINGⁱ

10116.ENSRNOP00000016182

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	94 – 146	BHLHInterPro annotationAdd BLAST		53

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	51 – 71	Sequence analysisAdd BLAST		21
Coiled coilⁱ	100 – 120	Sequence analysisAdd BLAST		21

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG410IQ4G Eukaryota ENOG41118Y2 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00680000099860
HOGENOMⁱ	HOG000049256
HOVERGENⁱ	HBG000250
KEGG Orthology (KO) More...KOⁱ	K09080
OMAⁱ	GSPHFDG
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G15AI
TreeFamⁱ	TF315153

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf IPR032650 Neurod6 IPR022575 Neurogenic_DUF IPR016637 TF_bHLH_NeuroD
PANTHERⁱ	PTHR19290:SF9 PTHR19290:SF9, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit PF12533 Neuro_bHLH, 1 hit
PIRSFⁱ	PIRSF015618 bHLH_NeuroD, 1 hit
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

B5DEY7-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLTLPFDESV VMPESQMCRK FARQCEDQKQ IKKPESFPKQ VVLRGKSIKR 
        60         70         80         90        100
APGEETEKEE EEEDREEEDE NGLPRRRGLR KKKTTKLRLE RVKFRRQEAN 
       110        120        130        140        150
ARERNRMHGL NDALDNLRKV VPCYSKTQKL SKIETLRLAK NYIWALSEIL 
       160        170        180        190        200
RIGKRPDLLT FVQNLCKGLS QPTTNLVAGC LQLNARSFLM GQGGEAAHHT 
       210        220        230        240        250
RSPYSTFYPP YHSPELATPP GHGTLDNSKS MKPYNYCSAY ESFYESTSPE 
       260        270        280        290        300
CASPQFEGPL SPPPINYNGI FSLKQEETLD YGKNYNYGMH YCAVPPRGPL 
       310        320        330 
GQGAMFRLPT DSHFPYDLHL RSQSLTMQDE LNAVFHN

Length:337

Mass (Da):38,654

Last modified:October 14, 2008 - v1

Checksum:ⁱCAF28ACC2C71EFBA

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07060615 Genomic DNA No translation available. BC168855 mRNA Translation: AAI68855.1 CH474011 Genomic DNA Translation: EDL88072.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001102707.1, NM_001109237.1
UniGeneⁱ	Rn.220502 Rn.84947

Genome annotation databases

Ensemblⁱ	ENSRNOT00000016182; ENSRNOP00000016182; ENSRNOG00000026055
GeneIDⁱ	500137
KEGGⁱ	rno:500137
UCSC genome browser More...UCSCⁱ	RGD:1562793 rat

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
B5DEY7	Neurogenic differentiation factor 6		MOUSE		337	UniRef90_P48986
Neurogenic differentiation factor 6		BOVIN		337
Neurogenic differentiation factor 6		HUMAN		337
Neurogenic differentiation factor 6		MACFA		337
Neurogenic differentiation factor		CERAT		337
+170

Protein	Similar proteins		Species	Score	Length	Source
B5DEY7	Neurogenic differentiation factor 6		MOUSE		337	UniRef50_P48986
Neurogenic differentiation factor 6		HUMAN		337
Neurogenic differentiation factor 6		MACFA		337
Neurogenic differentiation factor 6		BOVIN		337
Neurogenic differentiation factor 6-A		DANRE		327
+277

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07060615 Genomic DNA No translation available. BC168855 mRNA Translation: AAI68855.1 CH474011 Genomic DNA Translation: EDL88072.1
RefSeqⁱ	NP_001102707.1, NM_001109237.1
UniGeneⁱ	Rn.220502 Rn.84947

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000016182

STRINGⁱ

10116.ENSRNOP00000016182

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000016182; ENSRNOP00000016182; ENSRNOG00000026055
GeneIDⁱ	500137
KEGGⁱ	rno:500137
UCSCⁱ	RGD:1562793 rat

Organism-specific databases

CTDⁱ	63974
RGDⁱ	1562793 Neurod6

Phylogenomic databases

eggNOGⁱ	ENOG410IQ4G Eukaryota ENOG41118Y2 LUCA
GeneTreeⁱ	ENSGT00680000099860
HOGENOMⁱ	HOG000049256
HOVERGENⁱ	HBG000250
KOⁱ	K09080
OMAⁱ	GSPHFDG
OrthoDBⁱ	EOG091G15AI
TreeFamⁱ	TF315153

Gene expression databases

Bgeeⁱ	ENSRNOG00000026055 Expressed in 1 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000026055 Expressed in 1 organ(s), highest expression level in brain

Family and domain databases

CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf IPR032650 Neurod6 IPR022575 Neurogenic_DUF IPR016637 TF_bHLH_NeuroD
PANTHERⁱ	PTHR19290:SF9 PTHR19290:SF9, 1 hit
Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit PF12533 Neuro_bHLH, 1 hit
PIRSFⁱ	PIRSF015618 bHLH_NeuroD, 1 hit
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	B5DEY7_RAT
Accessionⁱ	B5DEY7Primary (citable) accession number: B5DEY7
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 14, 2008
	Last sequence update:	October 14, 2008
	Last modified:	September 12, 2018
	This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - B5DEY7 (B5DEY7_RAT)

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Neurogenic differentiation factor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ