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Protein

60 kDa chaperonin

Gene

groL

Organism
Prosthecochloris aestuarii (strain DSM 271 / SK 413)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPAES290512:G1GCD-684-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:Paes_0680
OrganismiProsthecochloris aestuarii (strain DSM 271 / SK 413)
Taxonomic identifieri290512 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeProsthecochloris
Proteomesi
  • UP000002725 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001300451 – 54960 kDa chaperoninAdd BLAST549

Proteomic databases

PRIDEiB4S6H2

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi290512.Paes_0680

Structurei

3D structure databases

ProteinModelPortaliB4S6H2
SMRiB4S6H2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9 Bacteria
COG0459 LUCA
HOGENOMiHOG000076290
KOiK04077
OMAiTDTDKME
OrthoDBiPOG091H00E7

Family and domain databases

CDDicd03344 GroEL, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
HAMAPiMF_00600 CH60, 1 hit
InterProiView protein in InterPro
IPR018370 Chaperonin_Cpn60_CS
IPR001844 Chaprnin_Cpn60
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00298 CHAPERONIN60
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 1 hit
TIGRFAMsiTIGR02348 GroEL, 1 hit
PROSITEiView protein in PROSITE
PS00296 CHAPERONINS_CPN60, 1 hit

Sequencei

Sequence statusi: Complete.

B4S6H2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAKDILFDA EARAKLKVGV DKLANAVKVT LGPAGRNVLI DKKFGAPTST
60 70 80 90 100
KDGVTVAKEV ELEDAFENMG AQMVREVSSK TSDVAGDGTT TATVLAQAIY
110 120 130 140 150
REGLKNVAAG ARPIDLKRGI DLAVKDVVAE LREISRDITG KKEIAQVGTI
160 170 180 190 200
SANNDPEIGE LIAEAMDKVG KDGVITVEEA KGMDTELTVV EGMQFDRGYL
210 220 230 240 250
SPYFVTNSEK MDADLEDPYI LIYDKKISNM KELLPVLEKT AQSGRPLMII
260 270 280 290 300
AEDIEGEALA TLVVNKLRGT LKVCAVKAPG FGDRRKAMLE DIAILTGGTV
310 320 330 340 350
ISEEKGYKLE NATISYLGQA ASITVDKDNT TIVDGKGQAD DIKARIGEIK
360 370 380 390 400
GQIEKSTSDY DTEKLQERLA KLSGGVAVLN IGASTEVEMK EKKARVEDAL
410 420 430 440 450
HATRAAVQEG IVAGGGVALI RAAKALDATN PENEDQKTGV DIIRRALEEP
460 470 480 490 500
LRQIVANTGT TDGAVVVEKV KNSEGDYGFN ARTEEYMNLI EAGVVDPTKV
510 520 530 540
TRTALENAAS VAGILLTTEA AITDIKEDGS DMPPMPGGMG GMGGMGGMM
Length:549
Mass (Da):58,252
Last modified:September 23, 2008 - v1
Checksum:iCB2D70C1F2F2F5D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001108 Genomic DNA Translation: ACF45727.1
RefSeqiWP_012505264.1, NC_011059.1

Genome annotation databases

EnsemblBacteriaiACF45727; ACF45727; Paes_0680
KEGGipaa:Paes_0680

Similar proteinsi

Entry informationi

Entry nameiCH60_PROA2
AccessioniPrimary (citable) accession number: B4S6H2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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