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Protein

Uracil-DNA glycosylase

Gene

ung

Organism
Neisseria gonorrhoeae (strain NCCP11945)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.UniRule annotation

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei61Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processDNA damage, DNA repair

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylaseUniRule annotation (EC:3.2.2.27UniRule annotation)
Short name:
UDGUniRule annotation
Gene namesi
Name:ungUniRule annotation
Ordered Locus Names:NGK_1026
OrganismiNeisseria gonorrhoeae (strain NCCP11945)
Taxonomic identifieri521006 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000002564 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000965961 – 219Uracil-DNA glycosylaseAdd BLAST219

Structurei

3D structure databases

ProteinModelPortaliB4RLL6
SMRiB4RLL6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229528
KOiK03648
OMAiQANGLCF

Family and domain databases

CDDicd10027 UDG_F1, 1 hit
Gene3Di3.40.470.10, 1 hit
HAMAPiMF_00148 UDG, 1 hit
InterProiView protein in InterPro
IPR002043 UDG_fam1
IPR018085 Ura-DNA_Glyclase_AS
IPR005122 Uracil-DNA_glycosylase-like
IPR036895 Uracil-DNA_glycosylase-like_sf
PANTHERiPTHR11264 PTHR11264, 1 hit
PfamiView protein in Pfam
PF03167 UDG, 1 hit
SMARTiView protein in SMART
SM00986 UDG, 1 hit
SUPFAMiSSF52141 SSF52141, 1 hit
TIGRFAMsiTIGR00628 ung, 1 hit
PROSITEiView protein in PROSITE
PS00130 U_DNA_GLYCOSYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

B4RLL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTWHDALGG EKQQPYFQEI LNAVRQERLS GQIIYPPEAD VFNAFRLTAF
60 70 80 90 100
DRVKVVILGQ DPYHGVGQAH GLAFSVRQGV RIPPSLLNIY KELETDIEGF
110 120 130 140 150
SIPAHGCLTA WAEQGILLLN TVLTVRAGQA HSHALLGWER FTDTVIRQLA
160 170 180 190 200
THRKHLVFML WGGYAQQKGR LIDSQNHLIL TAPHPSPLSA YRGFFGCRHF
210
SQANSYLSQH GIEPINWKL
Length:219
Mass (Da):24,688
Last modified:September 23, 2008 - v1
Checksum:i8B55F4010567E3E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001050 Genomic DNA Translation: ACF29703.1
RefSeqiWP_003688628.1, NC_011035.1

Genome annotation databases

EnsemblBacteriaiACF29703; ACF29703; NGK_1026
KEGGingk:NGK_1026

Similar proteinsi

Entry informationi

Entry nameiUNG_NEIG2
AccessioniPrimary (citable) accession number: B4RLL6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: October 25, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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