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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Phenylobacterium zucineum (strain HLK1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:PHZ_c2895
OrganismiPhenylobacterium zucineum (strain HLK1)
Taxonomic identifieri450851 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaePhenylobacterium
Proteomesi
  • UP000001868 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953881 – 593Arginine--tRNA ligaseAdd BLAST593

Proteomic databases

PRIDEiB4R8T9

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi450851.PHZ_c2895

Structurei

3D structure databases

ProteinModelPortaliB4R8T9
SMRiB4R8T9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B4R8T9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDLKTALGE AVEAAFAAEG VPAELARVTA SDRPDLADFQ SNGALAAAKR
60 70 80 90 100
VGKNPREIAT AVAGRLQGDP RLASVEIAGP GFLNLKVADA ALAARADAIA
110 120 130 140 150
ADPRAGAGTV PAPRRVIVDY GGPNVAKPMH VGHLRASIIG ESVKRLYRFR
160 170 180 190 200
GDTVIGDAHF GDWGYQMGLL IGAVCDEDAE IRALVDQLNA SGDPNGEIPA
210 220 230 240 250
AFERVTLADL DRLYPLAAAK GKEDPAYRDR ARKLTADLQA HKPGCYLLWR
260 270 280 290 300
RFRDVTQVAL ERDFHALGVD FDWWKGESDV DHLIQPMVAE LADKGLLVDD
310 320 330 340 350
QGARIVRVAR EGDKRELPPL LVVSSEGSAM YGTTDLATIL DRKREFDPQL
360 370 380 390 400
VIYCVDQRQA DHFEIVFRAA YLAGYAEEGQ LEHIGFGTMN GTDGKPFKTR
410 420 430 440 450
EGGVLKLADL IEMTRSKARE RLHEAGLGED LPAEEFEDIA GKVAVAALKF
460 470 480 490 500
ADLSNFRGTS YVFDLDRFTS FEGKTGPYLL YQAVRVKSLL RKAEAEGAQA
510 520 530 540 550
GPVTVAEPAE RDLVLTLDAF ETALQEAYDK KAPNALAEHA YRLSQAFSKF
560 570 580 590
YAACPILAAP PPVRGSRLTL AQATLRQLEL ALDILGIAVP ERM
Length:593
Mass (Da):64,241
Last modified:September 23, 2008 - v1
Checksum:i27945A89A03EC77D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000747 Genomic DNA Translation: ACG79304.1
RefSeqiWP_012523442.1, NC_011144.1

Genome annotation databases

EnsemblBacteriaiACG79304; ACG79304; PHZ_c2895
KEGGipzu:PHZ_c2895

Similar proteinsi

Entry informationi

Entry nameiSYR_PHEZH
AccessioniPrimary (citable) accession number: B4R8T9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: March 28, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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