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UniProtKB - B4PWD8 (B4PWD8_DROYA)
Protein
Submitted name:
Uncharacterized protein
Gene
Dyak\GE17743
Organism
Drosophila yakuba (Fruit fly)
Status
Functioni
GO - Molecular functioni
- ecdysteroid 25-hydroxylase activity Source: EnsemblMetazoa
- heme binding Source: InterPro
- iron ion binding Source: InterPro
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
GO - Biological processi
- border follicle cell migration Source: EnsemblMetazoa
- ecdysone biosynthetic process Source: EnsemblMetazoa
- embryonic development via the syncytial blastoderm Source: EnsemblMetazoa
Keywordsi
Molecular function | MonooxygenaseUniRule annotation, Oxidoreductase |
Ligand | HemeUniRule annotation, Iron, Metal-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:Dyak\GE17743Imported ORF Names:Dyak_GE17743Imported |
Organismi | Drosophila yakuba (Fruit fly)Imported |
Taxonomic identifieri | 7245 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Subcellular locationi
Endoplasmic reticulum
- endoplasmic reticulum Source: EnsemblMetazoa
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 20 – 39 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 119 – 139 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | FBgn0235189, Expressed in adult organism and 1 other tissue |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 305 – 343 | DisorderedSequence analysisAdd BLAST | 39 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 305 – 324 | Basic and acidic residuesSequence analysisAdd BLAST | 20 | |
Compositional biasi | 325 – 342 | Acidic residuesSequence analysisAdd BLAST | 18 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG0156, Eukaryota |
HOGENOMi | CLU_001570_22_0_1 |
OMAi | IMGGYGI |
OrthoDBi | 702827at2759 |
PhylomeDBi | B4PWD8 |
Family and domain databases
Gene3Di | 1.10.630.10, 1 hit |
InterProi | View protein in InterPro IPR001128, Cyt_P450 IPR017972, Cyt_P450_CS IPR002401, Cyt_P450_E_grp-I IPR036396, Cyt_P450_sf |
Pfami | View protein in Pfam PF00067, p450, 1 hit |
PRINTSi | PR00463, EP450I PR00385, P450 |
SUPFAMi | SSF48264, SSF48264, 1 hit |
PROSITEi | View protein in PROSITE PS00086, CYTOCHROME_P450, 1 hit |
i Sequence
Sequence statusi: Complete.
B4PWD8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSADIVDVVG GYTGWMPSVQ SLSFLLVPGA LVLVILYLCE REYDDILGVS
60 70 80 90 100
PPGPWGLPLL GYLPFLDGRA PHKSLQKLAQ RYGGIFELKM GRVRTVILTD
110 120 130 140 150
AALVRDFFRR DVMNGRAPLY LTHGIMGGFG IICAQLDIWR HARRETIDWL
160 170 180 190 200
KALGMTRRPG ELRARLERRI ARGVNECVQL FESEAKKSCA SEVDPLPALH
210 220 230 240 250
HSLGNIINDL VFGITYKRND PDWLYLQRLQ EEGVKLIGVS GVVNFLPWLR
260 270 280 290 300
HLPANKRNIR FLLEGKAKTH AIYDRIVEAC LQRLREKQQV FKELQEQKRL
310 320 330 340 350
QRQLAKEQRR QSKEASANQE RIEPEIAADE DDEEESDEED KFEPESILEH
360 370 380 390 400
FLVVRDTDSQ LYCDDQLRHL LADLFGAGVD TSLATLRWFL LYLAREQRCQ
410 420 430 440 450
RRLHELLLPL GPSPSLEELE SLAYLRACIS ETMRIRSVVP LGIPHGCKEE
460 470 480 490 500
AIMGDYNIKG GSMIVCLEWA IHMDPVAFPE PEQFRPERFL TPEGSYQAPP
510 520 530 540 550
QFIPFSSGYR MCPGEDMARM ILTLFTGRIL RRFHLELPPG TEVDMAGESG
560 570 580
ITLTPVPHKL RFTKLPAVEM RHEPDGSVLQ D
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CM000162 Genomic DNA Translation: EDX02756.1 |
RefSeqi | XP_002101648.1, XM_002101612.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0264261; FBpp0262753; FBgn0235189 |
GeneIDi | 6525828 |
KEGGi | dya:Dyak_GE17743 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CM000162 Genomic DNA Translation: EDX02756.1 |
RefSeqi | XP_002101648.1, XM_002101612.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7245.FBpp0262753 |
Genome annotation databases
EnsemblMetazoai | FBtr0264261; FBpp0262753; FBgn0235189 |
GeneIDi | 6525828 |
KEGGi | dya:Dyak_GE17743 |
Phylogenomic databases
eggNOGi | KOG0156, Eukaryota |
HOGENOMi | CLU_001570_22_0_1 |
OMAi | IMGGYGI |
OrthoDBi | 702827at2759 |
PhylomeDBi | B4PWD8 |
Gene expression databases
Bgeei | FBgn0235189, Expressed in adult organism and 1 other tissue |
Family and domain databases
Gene3Di | 1.10.630.10, 1 hit |
InterProi | View protein in InterPro IPR001128, Cyt_P450 IPR017972, Cyt_P450_CS IPR002401, Cyt_P450_E_grp-I IPR036396, Cyt_P450_sf |
Pfami | View protein in Pfam PF00067, p450, 1 hit |
PRINTSi | PR00463, EP450I PR00385, P450 |
SUPFAMi | SSF48264, SSF48264, 1 hit |
PROSITEi | View protein in PROSITE PS00086, CYTOCHROME_P450, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | B4PWD8_DROYA | |
Accessioni | B4PWD8Primary (citable) accession number: B4PWD8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 23, 2008 |
Last sequence update: | September 23, 2008 | |
Last modified: | May 25, 2022 | |
This is version 69 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |