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UniProtKB - B4PUM2 (PTER_DROYA)
Protein
Phosphotriesterase-related protein
Gene
GE25944
Organism
Drosophila yakuba (Fruit fly)
Status
Functioni
Cofactori
a divalent metal cationBy similarityNote: Binds 2 divalent metal cations per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 22 | Divalent metal cation 1; via tele nitrogenBy similarity | 1 | |
Metal bindingi | 24 | Divalent metal cation 1; via tele nitrogenBy similarity | 1 | |
Metal bindingi | 169 | Divalent metal cation 1By similarity | 1 | |
Metal bindingi | 169 | Divalent metal cation 2By similarity | 1 | |
Metal bindingi | 201 | Divalent metal cation 2; via pros nitrogenBy similarity | 1 | |
Metal bindingi | 230 | Divalent metal cation 2; via tele nitrogenBy similarity | 1 | |
Metal bindingi | 298 | Divalent metal cation 1By similarity | 1 |
GO - Molecular functioni
- hydrolase activity, acting on ester bonds Source: InterPro
- zinc ion binding Source: InterPro
GO - Biological processi
- catabolic process Source: InterPro
Keywordsi
Molecular function | Hydrolase |
Ligand | Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Phosphotriesterase-related protein (EC:3.1.-.-)Alternative name(s): Parathion hydrolase-related protein |
Gene namesi | ORF Names:GE25944 |
Organismi | Drosophila yakuba (Fruit fly) |
Taxonomic identifieri | 7245 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000388682 | 1 – 350 | Phosphotriesterase-related proteinAdd BLAST | 350 |
Expressioni
Gene expression databases
Bgeei | FBgn0242991, Expressed in adult organism and 1 other tissue |
Family & Domainsi
Sequence similaritiesi
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.PROSITE-ProRule annotation
Phylogenomic databases
eggNOGi | ENOG502QQQR, Eukaryota |
HOGENOMi | CLU_054760_0_1_1 |
OMAi | MVKCGFI |
OrthoDBi | 972282at2759 |
PhylomeDBi | B4PUM2 |
Family and domain databases
CDDi | cd00530, PTE, 1 hit |
InterProi | View protein in InterPro IPR017947, AryldialkylPase_Zn-BS IPR032466, Metal_Hydrolase IPR001559, Phosphotriesterase |
PANTHERi | PTHR10819, PTHR10819, 1 hit |
Pfami | View protein in Pfam PF02126, PTE, 1 hit |
SUPFAMi | SSF51556, SSF51556, 1 hit |
PROSITEi | View protein in PROSITE PS01322, PHOSPHOTRIESTERASE_1, 1 hit PS51347, PHOSPHOTRIESTERASE_2, 1 hit |
i Sequence
Sequence statusi: Complete.
B4PUM2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTVQTVLGT ITPNLLGRTL THEHVALDFE HFYRPPPPDF ESELKAKISM
60 70 80 90 100
STLGYVRLYP YSSKENVRFY DEEALEAAKK DVLLYKKHGG GSIVENSSYG
110 120 130 140 150
LKRNLEFIVE LAKSTGVHFI AGTGHYIHAM QDASHASLTV EQMSDLYSKD
160 170 180 190 200
IITGQQVNGQ MVKCGFIGEV ASVYPIHDFE KNAIKAAGEI QEVLGCGVSM
210 220 230 240 250
HPHRVTKAPF EIMRLYLEAG GRADKCVMSH LDRTIFDIDE LLEFAKLGCY
260 270 280 290 300
IQYDLFGTEC SFYQLNTSVD MISDGQRIDN LIKLIKEGLV DKLLMSHDIH
310 320 330 340 350
TKHRLTSYGG HGYHHIHTNI LPRMFDRGVT LEQVEQMTVT NPANWLAFDP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CM000160 Genomic DNA Translation: EDW96639.1 |
RefSeqi | XP_002096927.1, XM_002096891.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0272462; FBpp0270954; FBgn0242991 |
GeneIDi | 6536345 |
KEGGi | dya:Dyak_GE25944 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CM000160 Genomic DNA Translation: EDW96639.1 |
RefSeqi | XP_002096927.1, XM_002096891.2 |
3D structure databases
SMRi | B4PUM2 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7245.FBpp0270954 |
Genome annotation databases
EnsemblMetazoai | FBtr0272462; FBpp0270954; FBgn0242991 |
GeneIDi | 6536345 |
KEGGi | dya:Dyak_GE25944 |
Phylogenomic databases
eggNOGi | ENOG502QQQR, Eukaryota |
HOGENOMi | CLU_054760_0_1_1 |
OMAi | MVKCGFI |
OrthoDBi | 972282at2759 |
PhylomeDBi | B4PUM2 |
Gene expression databases
Bgeei | FBgn0242991, Expressed in adult organism and 1 other tissue |
Family and domain databases
CDDi | cd00530, PTE, 1 hit |
InterProi | View protein in InterPro IPR017947, AryldialkylPase_Zn-BS IPR032466, Metal_Hydrolase IPR001559, Phosphotriesterase |
PANTHERi | PTHR10819, PTHR10819, 1 hit |
Pfami | View protein in Pfam PF02126, PTE, 1 hit |
SUPFAMi | SSF51556, SSF51556, 1 hit |
PROSITEi | View protein in PROSITE PS01322, PHOSPHOTRIESTERASE_1, 1 hit PS51347, PHOSPHOTRIESTERASE_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PTER_DROYA | |
Accessioni | B4PUM2Primary (citable) accession number: B4PUM2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 3, 2009 |
Last sequence update: | September 23, 2008 | |
Last modified: | February 23, 2022 | |
This is version 51 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Drosophila annotation project |