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Protein

Importin subunit alpha

Gene

Dwil\GK17499

Organism
Drosophila willistoni (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Importin subunit alphaUniRule annotation
Gene namesi
Name:Dwil\GK17499Imported
ORF Names:Dwil_GK17499Imported, GK17499Imported
OrganismiDrosophila willistoni (Fruit fly)Imported
Taxonomic identifieri7260 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000007798 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0219498 Dwil\GK17499

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi7260.FBpp0246642

Structurei

3D structure databases

ProteinModelPortaliB4ML90
SMRiB4ML90
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 52IBBInterPro annotationAdd BLAST52
Repeati159 – 202ARMPROSITE-ProRule annotationAdd BLAST44
Repeati202 – 230ARMPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the importin alpha family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0166 Eukaryota
COG5064 LUCA
InParanoidiB4ML90
OMAiPYAITIE
OrthoDBiEOG091G095Z
PhylomeDBiB4ML90

Family and domain databases

Gene3Di1.20.5.690, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR032413 Arm_3
IPR000225 Armadillo
IPR002652 Importin-a_IBB
IPR036975 Importin-a_IBB_sf
IPR024931 Importing_su_alpha
PfamiView protein in Pfam
PF00514 Arm, 8 hits
PF16186 Arm_3, 1 hit
PF01749 IBB, 1 hit
PIRSFiPIRSF005673 Importin_alpha, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 8 hits
SUPFAMiSSF48371 SSF48371, 2 hits
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 2 hits
PS51214 IBB, 1 hit

Sequencei

Sequence statusi: Complete.

B4ML90-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSATHKQRYK NVGLDSTEMR RRREEVGIQL RKTKREQQLF KRRNVVLEPQ
60 70 80 90 100
TAGSGMDSSS SSELQSNDMQ MADSTTSGQM GKLLPGVVTQ QPDVTGLNQQ
110 120 130 140 150
QQQHQQQQQL LQTQSIINGE MIQMLYSDKE SDQLEATQKF RKLLSRDPNP
160 170 180 190 200
PIEEVIQKDI VPQFVNFLRN NTNATLQFEA AWTLTNIASG TSHQTKVVIE
210 220 230 240 250
AGAVPIFIEL LSSPHDDVQE QAVWALGNIA GDSPTCRDHL LSSGILVPLL
260 270 280 290 300
HVLSTSERIT MIRNAVWTLS NLCRGKNPPA DFAKIVHGLP ILARLLDYTD
310 320 330 340 350
VDVLSDTCWA ISYLSDGPND KIQAVIDAGV CRRLVELLLH PQQNVSTAAL
360 370 380 390 400
RAVGNIVTGD DQQTQVILSY NALPCISHLL RSSAETIRKE SCWTISNIAA
410 420 430 440 450
GNREQIQAII NANIFPQLMG IMQTAEFKTR KEAAWAITNA TSSGTSEQIN
460 470 480 490 500
YLVQVGCIPP MCDFLTVVDS DIVQVALNAL ENILKAGEKF QARPNPYAMA
510 520 530 540 550
IEQCGGLDKI EYLQAHENRD IYHKSFYIIE QYFGNEEEDA RVAPVAGSQQ
560
YEFNPHDLPE GGFNF
Length:565
Mass (Da):62,860
Last modified:September 23, 2008 - v1
Checksum:i66878636574E0E28
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH963847 Genomic DNA Translation: EDW73348.1
RefSeqiXP_002062362.1, XM_002062326.2

Genome annotation databases

EnsemblMetazoaiFBtr0248150; FBpp0246642; FBgn0219498
GeneIDi6639049
KEGGidwi:Dwil_GK17499

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH963847 Genomic DNA Translation: EDW73348.1
RefSeqiXP_002062362.1, XM_002062326.2

3D structure databases

ProteinModelPortaliB4ML90
SMRiB4ML90
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7260.FBpp0246642

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0248150; FBpp0246642; FBgn0219498
GeneIDi6639049
KEGGidwi:Dwil_GK17499

Organism-specific databases

FlyBaseiFBgn0219498 Dwil\GK17499

Phylogenomic databases

eggNOGiKOG0166 Eukaryota
COG5064 LUCA
InParanoidiB4ML90
OMAiPYAITIE
OrthoDBiEOG091G095Z
PhylomeDBiB4ML90

Family and domain databases

Gene3Di1.20.5.690, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR032413 Arm_3
IPR000225 Armadillo
IPR002652 Importin-a_IBB
IPR036975 Importin-a_IBB_sf
IPR024931 Importing_su_alpha
PfamiView protein in Pfam
PF00514 Arm, 8 hits
PF16186 Arm_3, 1 hit
PF01749 IBB, 1 hit
PIRSFiPIRSF005673 Importin_alpha, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 8 hits
SUPFAMiSSF48371 SSF48371, 2 hits
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 2 hits
PS51214 IBB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB4ML90_DROWI
AccessioniPrimary (citable) accession number: B4ML90
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: September 12, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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