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Protein

G protein-coupled receptor kinase

Gene

Dvir\GJ19694

Organism
Drosophila virilis (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei318Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
G protein-coupled receptor kinaseUniRule annotation (EC:2.7.11.-UniRule annotation)
Gene namesi
Name:Dvir\GJ19694Imported
ORF Names:Dvir_GJ19694Imported, GJ19694Imported
OrganismiDrosophila virilis (Fruit fly)Imported
Taxonomic identifieri7244 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
Proteomesi
  • UP000008792 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0206836 Dvir\GJ19694

Expressioni

Gene expression databases

BgeeiFBgn0206836

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiB4MCJ4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 175RGSInterPro annotationAdd BLAST122
Domaini191 – 454Protein kinaseInterPro annotationAdd BLAST264
Domaini455 – 522AGC-kinase C-terminalInterPro annotationAdd BLAST68
Domaini557 – 657PHInterPro annotationAdd BLAST101

Sequence similaritiesi

Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0986 Eukaryota
ENOG410YRQZ LUCA
InParanoidiB4MCJ4
KOiK00910
OrthoDBiEOG091G0AEI

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR000239 GPCR_kinase
IPR011009 Kinase-like_dom_sf
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR016137 RGS
IPR036305 RGS_sf
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00069 Pkinase, 1 hit
PF00615 RGS, 1 hit
PRINTSiPR00717 GPCRKINASE
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00315 RGS, 1 hit
SM00133 S_TK_X, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF48097 SSF48097, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS50003 PH_DOMAIN, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS50132 RGS, 1 hit

Sequencei

Sequence statusi: Complete.

B4MCJ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADLEAVLAD VSYLMAMEKS KCTPAARASK KLILPDPSVR SVMYKYLEKE
60 70 80 90 100
NELNFHNIFN QIIGYLLFKD FCENDSDEPI QQLKFYEQIK NFEKTECYEE
110 120 130 140 150
RKKMAREIYD NFIMEEMLSH TYEYSKDAVA NVQKYLLKNE VPVNLFEPYM
160 170 180 190 200
DEIFGQLKGR PFKKFLESDK FTRFCQWKNL ELNIQLSMND FSVHRIIGRG
210 220 230 240 250
GFGEVYGCRK ADTGKMYAMK CLDKKRIKMK QGEMLALNER NMLQAVSTGI
260 270 280 290 300
DCPFIVCMTY AFHTPDKLCF ILDLMNGGDL HYHLSQHGVF SEDEMKFYAA
310 320 330 340 350
EVILGLEHMH KRYIVYRDLK PANILLDENG HIRISDLGLA CDYSRKKPHA
360 370 380 390 400
SVGTHGYMSP EVLSKGTSYD SCADWFSFGC MLYKLLKGHS PFRQHKTKDK
410 420 430 440 450
HEIDRMTLTM NVELPDSFSV ELRNLLDMLL QRDVPKRLGC MGNGADEVKM
460 470 480 490 500
HNFFSGIDWH QVYIQKYTPP LVPPRGEVNA ADAFDIGSFD EEDTKGIKLN
510 520 530 540 550
DNDQDLYKHF SLTISERWQQ EVSETVFETI NSETDKIEHK KKAKQKQHFD
560 570 580 590 600
ADEKESDCIL HGYIKKLGGS FASLWQTKYA KLYPNRLELY SDSGNNKPEL
610 620 630 640 650
IFLDQVEDVS SDFVHYKNEQ CIQIRVNDGS RDGRIILTNS DEIGLKEWAL
660 670 680 690 700
SLRSAHKMSQ DLLGSMAKKA GKIYGSERDA NKSMYILGGN CSTTSSNGSK
Length:700
Mass (Da):80,711
Last modified:January 20, 2016 - v2
Checksum:i440D6557BD6BB2C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH940659 Genomic DNA Translation: EDW71382.2
RefSeqiXP_002058847.2, XM_002058811.2

Genome annotation databases

EnsemblMetazoaiFBtr0443939; FBpp0400302; FBgn0206836
GeneIDi6635312
KEGGidvi:Dvir_GJ19694

Similar proteinsi

Entry informationi

Entry nameiB4MCJ4_DROVI
AccessioniPrimary (citable) accession number: B4MCJ4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: January 20, 2016
Last modified: June 20, 2018
This is version 81 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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