UniProtKB - B4KTK4 (CIAO1_DROMO)
Protein
Probable cytosolic iron-sulfur protein assembly protein Ciao1
Gene
Ciao1
Organism
Drosophila mojavensis (Fruit fly)
Status
Functioni
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.UniRule annotation
GO - Biological processi
- iron-sulfur cluster assembly Source: UniProtKB
Names & Taxonomyi
Protein namesi | Recommended name: Probable cytosolic iron-sulfur protein assembly protein Ciao1UniRule annotation |
Gene namesi | Name:Ciao1UniRule annotation ORF Names:GI18956 |
Organismi | Drosophila mojavensis (Fruit fly) |
Taxonomic identifieri | 7230 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › |
Proteomesi |
|
Subcellular locationi
Cytosol
- CIA complex Source: InterPro
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000382487 | 1 – 331 | Probable cytosolic iron-sulfur protein assembly protein Ciao1Add BLAST | 331 |
Proteomic databases
PRIDEi | B4KTK4 |
Expressioni
Gene expression databases
Bgeei | FBgn0141695 Expressed in 2 organ(s), highest expression level in head |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 12 – 51 | WD 1Add BLAST | 40 | |
Repeati | 57 – 96 | WD 2Add BLAST | 40 | |
Repeati | 97 – 136 | WD 3Add BLAST | 40 | |
Repeati | 142 – 181 | WD 4Add BLAST | 40 | |
Repeati | 188 – 227 | WD 5Add BLAST | 40 | |
Repeati | 246 – 285 | WD 6Add BLAST | 40 | |
Repeati | 297 – 331 | WD 7Add BLAST | 35 |
Sequence similaritiesi
Belongs to the WD repeat CIA1 family.UniRule annotation
Keywords - Domaini
Repeat, WD repeatPhylogenomic databases
InParanoidi | B4KTK4 |
OMAi | EFECAAV |
OrthoDBi | 793298at2759 |
PhylomeDBi | B4KTK4 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
HAMAPi | MF_03037 ciao1, 1 hit |
InterProi | View protein in InterPro IPR028608 CIAO1/Cia1 IPR020472 G-protein_beta_WD-40_rep IPR015943 WD40/YVTN_repeat-like_dom_sf IPR001680 WD40_repeat IPR019775 WD40_repeat_CS IPR017986 WD40_repeat_dom IPR036322 WD40_repeat_dom_sf |
PANTHERi | PTHR19920 PTHR19920, 1 hit |
Pfami | View protein in Pfam PF00400 WD40, 6 hits |
PRINTSi | PR00320 GPROTEINBRPT |
SMARTi | View protein in SMART SM00320 WD40, 7 hits |
SUPFAMi | SSF50978 SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS00678 WD_REPEATS_1, 1 hit PS50082 WD_REPEATS_2, 6 hits PS50294 WD_REPEATS_REGION, 1 hit |
i Sequence
Sequence statusi: Complete.
B4KTK4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGRLILEHTL QGHKGRIWGV AWHPKGNSFA SCGEDKAIRI WSLSGNTWTT
60 70 80 90 100
KTILSDGHKR TIREVRWSPC GEYLASASFD ATTAIWSKHE CTATLEGHEN
110 120 130 140 150
EVKSVSWSRS GGLLATCSRD KSVWIWEVAG DDEFECAAVL NAHSQDVKRV
160 170 180 190 200
VWHPTKEILA SASYDNTIKM YAESALDSDW DCTATLSSHT STVWSIDFDA
210 220 230 240 250
DGERLVSCSD DATLKIWRAY HPGNEAGIAT PDKTTVWKCV CTLSGLHTRA
260 270 280 290 300
IYDVSWCKLT GLIASACGDD AIRIFKESSD SKRDAPSFEL LTSEESAHEQ
310 320 330
DVNAVEWNPV NVGQLISCSD DGTIKIWKLQ E
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH933808 Genomic DNA Translation: EDW09587.1 |
RefSeqi | XP_002005652.1, XM_002005616.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0169681; FBpp0168173; FBgn0141695 |
GeneIDi | 6579773 |
KEGGi | dmo:Dmoj_GI18956 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH933808 Genomic DNA Translation: EDW09587.1 |
RefSeqi | XP_002005652.1, XM_002005616.2 |
3D structure databases
SMRi | B4KTK4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7230.FBpp0168173 |
Proteomic databases
PRIDEi | B4KTK4 |
Genome annotation databases
EnsemblMetazoai | FBtr0169681; FBpp0168173; FBgn0141695 |
GeneIDi | 6579773 |
KEGGi | dmo:Dmoj_GI18956 |
Phylogenomic databases
InParanoidi | B4KTK4 |
OMAi | EFECAAV |
OrthoDBi | 793298at2759 |
PhylomeDBi | B4KTK4 |
Gene expression databases
Bgeei | FBgn0141695 Expressed in 2 organ(s), highest expression level in head |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
HAMAPi | MF_03037 ciao1, 1 hit |
InterProi | View protein in InterPro IPR028608 CIAO1/Cia1 IPR020472 G-protein_beta_WD-40_rep IPR015943 WD40/YVTN_repeat-like_dom_sf IPR001680 WD40_repeat IPR019775 WD40_repeat_CS IPR017986 WD40_repeat_dom IPR036322 WD40_repeat_dom_sf |
PANTHERi | PTHR19920 PTHR19920, 1 hit |
Pfami | View protein in Pfam PF00400 WD40, 6 hits |
PRINTSi | PR00320 GPROTEINBRPT |
SMARTi | View protein in SMART SM00320 WD40, 7 hits |
SUPFAMi | SSF50978 SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS00678 WD_REPEATS_1, 1 hit PS50082 WD_REPEATS_2, 6 hits PS50294 WD_REPEATS_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CIAO1_DROMO | |
Accessioni | B4KTK4Primary (citable) accession number: B4KTK4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 1, 2009 |
Last sequence update: | September 23, 2008 | |
Last modified: | May 8, 2019 | |
This is version 58 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Drosophila annotation project |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families