UniProtKB - B4JDU5 (KRR1_DROGR)
Protein
KRR1 small subunit processome component homolog
Gene
dbe
Organism
Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi)
Status
Functioni
Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Binds to RNA. Required for female germline development, cell viability during eye development and for survival of dividing cells and epithelial cells during early wing disk development (By similarity).By similarity
GO - Molecular functioni
- RNA binding Source: UniProtKB-KW
GO - Biological processi
- multicellular organism development Source: UniProtKB-KW
- rRNA processing Source: UniProtKB-KW
Keywordsi
Molecular function | Developmental protein, Ribonucleoprotein, RNA-binding |
Biological process | Ribosome biogenesis, rRNA processing |
Names & Taxonomyi
Protein namesi | Recommended name: KRR1 small subunit processome component homologBy similarityAlternative name(s): KRR-R motif-containing protein 1By similarity Protein dribbleBy similarity |
Gene namesi | Name:dbeBy similarity Synonyms:dribbleBy similarity ORF Names:GH10489 |
Organismi | Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi) |
Taxonomic identifieri | 7222 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Hawaiian Drosophila › |
Proteomesi |
|
Subcellular locationi
Nucleus
- nucleolus By similarity
Nucleus
- nucleolus Source: UniProtKB-SubCell
- nucleoplasm Source: EnsemblMetazoa
Other locations
- ribonucleoprotein complex Source: EnsemblMetazoa
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000415653 | 1 – 341 | KRR1 small subunit processome component homologAdd BLAST | 341 |
Interactioni
Subunit structurei
Monomer.
Component of the ribosomal small subunit (SSU) processome (By similarity).
By similarityProtein-protein interaction databases
STRINGi | 7222.FBpp0144395 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 126 – 194 | KHSequence analysisAdd BLAST | 69 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 271 – 341 | Sequence analysisAdd BLAST | 71 |
Sequence similaritiesi
Belongs to the KRR1 family.Sequence analysis
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | KOG2874, Eukaryota |
HOGENOMi | CLU_040185_0_2_1 |
InParanoidi | B4JDU5 |
OMAi | VHKKEKF |
OrthoDBi | 944899at2759 |
PhylomeDBi | B4JDU5 |
Family and domain databases
Gene3Di | 3.30.1370.10, 2 hits |
InterProi | View protein in InterPro IPR041174, KH_8 IPR004087, KH_dom IPR036612, KH_dom_type_1_sf IPR024166, rRNA_assembly_KRR1 |
PANTHERi | PTHR12581, PTHR12581, 1 hit |
Pfami | View protein in Pfam PF17903, KH_8, 1 hit |
PIRSFi | PIRSF006515, KRR1, 1 hit |
SMARTi | View protein in SMART SM00322, KH, 1 hit |
SUPFAMi | SSF54791, SSF54791, 1 hit |
i Sequence
Sequence statusi: Complete.
B4JDU5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDSETEETT KQSTEPVDNA WSLKIPTFKA EDNPHGMVEE SSFATLFPKY
60 70 80 90 100
REKYLKEVWP LVQQTVAEHH LRAELDLIEG SMVVKTTRKT WDPYIIIKSR
110 120 130 140 150
DMIKLMARSV PFEQAKRVLQ DETGCDIIKI GNLVHKKEKF VKRRQRLIGP
160 170 180 190 200
NGATLKSIEL LTDCYVLVQG NTVAALGPYK GLQQVRDIVL ETMNNVHPIY
210 220 230 240 250
NIKALMIKRE LMKDPQLANE DWSRFLPKFK NKNISKRKQP KSRKPKGEYT
260 270 280 290 300
PFPPAQPESK IDKQLASGEY FLNKEQKQAK RQQERVAKQA EAAKKQDERR
310 320 330 340
NKDFMPPTED SPEQNRKRPS EASKVDVKAL KAKLLKANKQ K
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH916368 Genomic DNA Translation: EDW03465.1 |
RefSeqi | XP_001988598.1, XM_001988562.1 |
Genome annotation databases
EnsemblMetazoai | FBtr0145903; FBpp0144395; FBgn0117970 |
GeneIDi | 6562924 |
KEGGi | dgr:Dgri_GH10489 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH916368 Genomic DNA Translation: EDW03465.1 |
RefSeqi | XP_001988598.1, XM_001988562.1 |
3D structure databases
SMRi | B4JDU5 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7222.FBpp0144395 |
Genome annotation databases
EnsemblMetazoai | FBtr0145903; FBpp0144395; FBgn0117970 |
GeneIDi | 6562924 |
KEGGi | dgr:Dgri_GH10489 |
Phylogenomic databases
eggNOGi | KOG2874, Eukaryota |
HOGENOMi | CLU_040185_0_2_1 |
InParanoidi | B4JDU5 |
OMAi | VHKKEKF |
OrthoDBi | 944899at2759 |
PhylomeDBi | B4JDU5 |
Family and domain databases
Gene3Di | 3.30.1370.10, 2 hits |
InterProi | View protein in InterPro IPR041174, KH_8 IPR004087, KH_dom IPR036612, KH_dom_type_1_sf IPR024166, rRNA_assembly_KRR1 |
PANTHERi | PTHR12581, PTHR12581, 1 hit |
Pfami | View protein in Pfam PF17903, KH_8, 1 hit |
PIRSFi | PIRSF006515, KRR1, 1 hit |
SMARTi | View protein in SMART SM00322, KH, 1 hit |
SUPFAMi | SSF54791, SSF54791, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | KRR1_DROGR | |
Accessioni | B4JDU5Primary (citable) accession number: B4JDU5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 22, 2012 |
Last sequence update: | September 23, 2008 | |
Last modified: | December 2, 2020 | |
This is version 53 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Drosophila annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families