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Protein

DNA ligase

Gene

Dgri\GH20192

Organism
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dgri\GH20192Imported
ORF Names:Dgri_GH20192Imported
OrganismiDrosophila grimshawi (Fruit fly) (Idiomyia grimshawi)Imported
Taxonomic identifieri7222 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaHawaiian Drosophila
Proteomesi
  • UP000001070 Componenti: Unassembled WGS sequence

Subcellular locationi

Interactioni

Protein-protein interaction databases

STRINGi7222.FBpp0154098

Structurei

3D structure databases

ProteinModelPortaliB4J642
SMRiB4J642
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini402 – 538DNA_LIGASE_A3InterPro annotationAdd BLAST137

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0967 Eukaryota
COG1793 LUCA
InParanoidiB4J642
KOiK10747
OMAiWIKYKRD
OrthoDBiEOG091G06OS
PhylomeDBiB4J642

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

B4J642-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEPMEPLPS KQKIISLTSD SNESEGTDIY NPSLELYHPI NHAYWRAEGV
60 70 80 90 100
TPYLALARTF QVIEETKGRL KMIDILSNFF CSVMMVSPED LVPCVYLSIN
110 120 130 140 150
QLAPAYEGLE LGVAETTLMK AICKATGRNL AHIKSQTQLI GDLGIVAEQS
160 170 180 190 200
RVSQRMMFRP KPLNVRAVFA KLKEIANISG QSKITLVYDI FVACRLSEAR
210 220 230 240 250
FFIRSLIGKL RIGIAEQSLL TALAIALVKK LHINDCKRID KVAEIYKDEI
260 270 280 290 300
AETTLILKTT FCQCPNYDII IPAILKYDIE ELQERCPMHP GMPLRPMLAQ
310 320 330 340 350
PTKGVHEVLE RFSGMHITCE WKYDGERAQI HLNEQGEISI FSRNSENNTP
360 370 380 390 400
KYPDLIARSK PILKTEVKSY ILDSEIVAWD IERKQILPFQ ILSTRKRKNV
410 420 430 440 450
DIDDIKVQVC VYIFDLLYIN GKSLVTQPLS ERRKILFEHF QEVEGEWKFA
460 470 480 490 500
TALNTNDMDE VQQFLEESIK GNCEGLMVKT LDEEATYEIA KRSRNWLKLK
510 520 530 540 550
KDYLSNVGDS LDLVVIGGYK GKGRRTGIYG GFLLACYDTD NEEYQTICKI
560 570 580 590 600
GTGFTDEDLR QHSEFFSTNK LSEAKSYFRY DSSLEPDDWF EPCQVWEVKC
610 620 630 640 650
ADLSLSPIHR AGIGIVDAER GISLRFPRFI RIRDDKSPEN ATDANQVAHM
660 670
YSSQDVVKNN QKSSNSMDLE SDFY
Length:674
Mass (Da):76,917
Last modified:September 23, 2008 - v1
Checksum:i31302D18EA11CE00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH916367 Genomic DNA Translation: EDW01900.1
RefSeqiXP_001987033.1, XM_001986997.1

Genome annotation databases

EnsemblMetazoaiFBtr0459884; FBpp0410323; FBgn0127656
GeneIDi6559920
KEGGidgr:Dgri_GH20192

Similar proteinsi

Entry informationi

Entry nameiB4J642_DROGR
AccessioniPrimary (citable) accession number: B4J642
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 18, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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