UniProtKB - B4IJE9 (B4IJE9_DROSE)
Protein
Protein lin-7 homolog
Gene
Dsec\GM17757
Organism
Drosophila sechellia (Fruit fly)
Status
Functioni
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.UniRule annotation
GO - Molecular functioni
- L27 domain binding Source: UniProtKB-UniRule
GO - Biological processi
- border follicle cell migration Source: EnsemblMetazoa
- exocytosis Source: UniProtKB-UniRule
- neurotransmitter secretion Source: UniProtKB-UniRule
- protein transport Source: UniProtKB-UniRule
- regulation of synaptic growth at neuromuscular junction Source: EnsemblMetazoa
Keywordsi
Biological process | ExocytosisUniRule annotationARBA annotation, Protein transportUniRule annotationARBA annotation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Protein lin-7 homologUniRule annotation |
Gene namesi | Name:Dsec\GM17757Imported ORF Names:Dsec_GM17757Imported |
Organismi | Drosophila sechellia (Fruit fly)Imported |
Taxonomic identifieri | 7238 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
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Subcellular locationi
Plasma membrane
- Cell membrane UniRule annotationARBA annotation; Peripheral membrane protein UniRule annotationARBA annotation
Other locations
- Cell junction ARBA annotation
- Membrane ARBA annotation; Peripheral membrane protein ARBA annotation
Plasma Membrane
- basolateral plasma membrane Source: UniProtKB-UniRule
- MPP7-DLG1-LIN7 complex Source: UniProtKB-UniRule
- postsynaptic membrane Source: EnsemblMetazoa
- subapical complex Source: EnsemblMetazoa
Other locations
- presynapse Source: UniProtKB-UniRule
Keywords - Cellular componenti
Cell junctionUniRule annotationARBA annotation, Cell membraneUniRule annotationARBA annotation, MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 10 – 65 | L27InterPro annotationAdd BLAST | 56 | |
Domaini | 93 – 175 | PDZInterPro annotationAdd BLAST | 83 |
Sequence similaritiesi
Phylogenomic databases
HOGENOMi | CLU_097962_0_0_1 |
OMAi | MENRFER |
PhylomeDBi | B4IJE9 |
Family and domain databases
Gene3Di | 2.30.42.10, 1 hit |
InterProi | View protein in InterPro IPR014775, L27_C IPR004172, L27_dom IPR036892, L27_dom_sf IPR017365, LIN7 IPR001478, PDZ IPR036034, PDZ_sf |
Pfami | View protein in Pfam PF02828, L27, 1 hit PF00595, PDZ, 1 hit |
PIRSFi | PIRSF038039, Lin-7_homologue, 2 hits |
SMARTi | View protein in SMART SM00569, L27, 1 hit SM00228, PDZ, 1 hit |
SUPFAMi | SSF101288, SSF101288, 1 hit SSF50156, SSF50156, 1 hit |
PROSITEi | View protein in PROSITE PS51022, L27, 1 hit PS50106, PDZ, 1 hit |
i Sequence
Sequence statusi: Complete.
B4IJE9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADNAEPLTL SRDVKRSIEL LEKLQASGDF PTTKLAALQK VLNSDFMTSV
60 70 80 90 100
REVYEHVYET VDIQGSHDVR ASATAKATVA AFAASEGHAH PRVVELPKTE
110 120 130 140 150
EGLGFNVMGG KEQNSPIYIS RIIPGGVADR HGGLKRGDQL LSVNGVSVEG
160 170 180 190
ENHEKAVELL KQAVGSVKLV VRYTPKVLEE MEMRFDKQRN TRRRQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH480848 Genomic DNA Translation: EDW51140.1 |
RefSeqi | XP_002043859.1, XM_002043823.1 |
Genome annotation databases
EnsemblMetazoai | FBtr0200742; FBpp0199234; FBgn0172665 |
GeneIDi | 6619644 |
KEGGi | dse:6619644 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH480848 Genomic DNA Translation: EDW51140.1 |
RefSeqi | XP_002043859.1, XM_002043823.1 |
3D structure databases
SMRi | B4IJE9 |
ModBasei | Search... |
Genome annotation databases
EnsemblMetazoai | FBtr0200742; FBpp0199234; FBgn0172665 |
GeneIDi | 6619644 |
KEGGi | dse:6619644 |
Phylogenomic databases
HOGENOMi | CLU_097962_0_0_1 |
OMAi | MENRFER |
PhylomeDBi | B4IJE9 |
Family and domain databases
Gene3Di | 2.30.42.10, 1 hit |
InterProi | View protein in InterPro IPR014775, L27_C IPR004172, L27_dom IPR036892, L27_dom_sf IPR017365, LIN7 IPR001478, PDZ IPR036034, PDZ_sf |
Pfami | View protein in Pfam PF02828, L27, 1 hit PF00595, PDZ, 1 hit |
PIRSFi | PIRSF038039, Lin-7_homologue, 2 hits |
SMARTi | View protein in SMART SM00569, L27, 1 hit SM00228, PDZ, 1 hit |
SUPFAMi | SSF101288, SSF101288, 1 hit SSF50156, SSF50156, 1 hit |
PROSITEi | View protein in PROSITE PS51022, L27, 1 hit PS50106, PDZ, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B4IJE9_DROSE | |
Accessioni | B4IJE9Primary (citable) accession number: B4IJE9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 23, 2008 |
Last sequence update: | September 23, 2008 | |
Last modified: | December 2, 2020 | |
This is version 66 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |