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Protein
Submitted name:

GM12377

Gene

Dsec\GM12377

Organism
Drosophila sechellia (Fruit fly)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei1454Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protein phosphataseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
GM12377Imported
Gene namesi
Name:Dsec\GM12377Imported
ORF Names:Dsec_GM12377Imported, GM12377Imported
OrganismiDrosophila sechellia (Fruit fly)Imported
Taxonomic identifieri7238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000001292 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0167314 Dsec\GM12377

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliB4I0T6
SMRiB4I0T6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 155Fibronectin type-IIIInterPro annotationAdd BLAST95
Domaini176 – 272Fibronectin type-IIIInterPro annotationAdd BLAST97
Domaini362 – 460Fibronectin type-IIIInterPro annotationAdd BLAST99
Domaini461 – 552Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini553 – 635Fibronectin type-IIIInterPro annotationAdd BLAST83
Domaini637 – 735Fibronectin type-IIIInterPro annotationAdd BLAST99
Domaini740 – 830Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini831 – 920Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini935 – 1035Fibronectin type-IIIInterPro annotationAdd BLAST101
Domaini1258 – 1513Tyrosine-protein phosphataseInterPro annotationAdd BLAST256
Domaini1430 – 1504TYR_PHOSPHATASE_2InterPro annotationAdd BLAST75

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1554 – 1574Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

KOiK05694
OMAiIEDMHYG
OrthoDBiEOG091G00JF
PhylomeDBiB4I0T6

Family and domain databases

CDDicd00063 FN3, 8 hits
Gene3Di2.60.40.10, 8 hits
3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR000387 TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00041 fn3, 7 hits
PF00102 Y_phosphatase, 1 hit
PRINTSiPR00700 PRTYPHPHTASE
SMARTiView protein in SMART
SM00060 FN3, 10 hits
SM00194 PTPc, 1 hit
SM00404 PTPc_motif, 1 hit
SUPFAMiSSF49265 SSF49265, 5 hits
SSF52799 SSF52799, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 9 hits
PS00383 TYR_PHOSPHATASE_1, 1 hit
PS50056 TYR_PHOSPHATASE_2, 1 hit
PS50055 TYR_PHOSPHATASE_PTP, 1 hit

Sequencei

Sequence statusi: Complete.

B4I0T6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDCATRKQQQ LRAHHQQQQI QIQRQTYGRK RRQLQKQHHN LHHHYYHHNQ
60 70 80 90 100
QQQQKHFVWL VVGILTIYLA QHANAADLVI NVPNASSNAN AFYRIDYSPP
110 120 130 140 150
FGFPEPNTTI PASDIGKDIK FSRALPGTEY NFWLYYTNST HRSSYWTLVT
160 170 180 190 200
HLPKTHCISK SLSARCIFLK RAEPNTPGKF IVWFRNETTL LVLWQPPFPA
210 220 230 240 250
GIYTHYRVSI TPDDAIQSVL YVEREGEPPG PAQAAFKGLV PGREYNISVQ
260 270 280 290 300
TVSEDETSSV PTTARYLTVP ERVLNVTFDE AYTTSSSFRV RWGAAANLQR
310 320 330 340 350
IRCLPVMLST SRIFNVPRAP NSDSVYFDYP DVLEPGRTYE VVVKTIADNV
360 370 380 390 400
NSWPASGEVT LRPRPVRSLG GFLDDRRNAL HISWEPAETG RQDSYRISYH
410 420 430 440 450
EQTNASEVPA PFPVAAESQI TTNLTEYTLD SLLAGRRYLI AVQALSKGVA
460 470 480 490 500
SNASDITRYT RPAAPLIQEL RSIDQGLMLS WRSDVNSRQD RYEVHYQRNG
510 520 530 540 550
TREERTMATN ETSLTIHYLH PGSGYEVKVH AISHGVRSEP HSYFQAVFPK
560 570 580 590 600
PPQNLTLQTV HTNLVVLHWQ PPEGSDFSEY VVRYRTDASP WQRISGLHEN
610 620 630 640 650
EARIKDMHYG ERYLVQVNTV SFGVESPHPL ELNVTMPPQP VSNVVPLVDS
660 670 680 690 700
RNLTLEWPRP DGHVDFYTLK WWPTDEEDRV EFKNVTQLED LSSPSVRIPI
710 720 730 740 750
EDLSPGRQYR FEVQASSNGI RSGTTHLSTR TMPLIQSDVF IANAGHEQGQ
760 770 780 790 800
DETITLSYTP TPADSTRFDI YRFSMGDPTI KDKEKLANDT ERKLSFSGLT
810 820 830 840 850
PGKLYNVTVW TVSGGVASLP VQRLYRLYPL PISDLNAIQV AAREITLHWT
860 870 880 890 900
APAGEYTDFE LQYLSADEEA PQLLQNVTKN TEITLQGLRP YHNYTFTVVV
910 920 930 940 950
RSGSTQGADS ADVSVSTLMR SSAPISASYQ TLTAPPGKVE YFQPSDVQPG
960 970 980 990 1000
EVTFEWSLEP AEQHGPIDYF RITCQNADDA ADVSSYEFPV NATQGKIDGL
1010 1020 1030 1040 1050
VPGNHYIFRI QAKSALGYGA EREHIQTMPI LAPPVPEPSV TPLEVSRTSS
1060 1070 1080 1090 1100
TIEISFRQGY FSNAHGMVRS YTIIIAEDVG KNASGLEMPS WQDVQAYTVW
1110 1120 1130 1140 1150
LPYQAIEPYN PFLTSNGSRK NSLEAEHFTI GTANCEKHQA GYCNGPLRAG
1160 1170 1180 1190 1200
TTYRIKIRAF TDEDKFTDTV YSSPITTERS DTVIVAATVS AVLLVAMVLA
1210 1220 1230 1240 1250
VVYCQHRCQL IRRASKLARM QDELAALPEG YITPNRPVHV KDFSEHYRIM
1260 1270 1280 1290 1300
SADSDFRFSE EFEELKHVGR DQACSFANLP CNRPKNRFTN ILPYDHSRFK
1310 1320 1330 1340 1350
LQPVDDDDGS DYINANYMPG HNSPREFIVT QGPLHSTREE FWRMCWESNS
1360 1370 1380 1390 1400
RAIVMLTRCF EKGREKCDQY WPVDRVAMFY GDIKVQLIID THYHDWSISE
1410 1420 1430 1440 1450
FMVSRNCESR IMRHFHFTTW PDFGVPEPPQ SLVRFVRAFR DVIGTDMRPI
1460 1470 1480 1490 1500
IVHCSAGVGR SGTFIALDRI LQHIHKSDYV DIFGIVFAMR KERVFMVQTE
1510 1520 1530 1540 1550
QQYVCIHQCL LAVLEGKEHL LADSLELHAN DGYEERQPQT KMGTLPIRAS
1560 1570 1580 1590 1600
LAMAEKLDAD LMTNKDEVED QEQQQLQLAT EEKPKGDDEE VDDDDDDEDD
1610 1620 1630 1640 1650
DQQPLNNETT ATLSSASCSS STHDVHVVLQ EAIEHPKQEQ EQSHADTESE
1660 1670
TTDSDDDDED GDGKVAKDGA VADEDGWWY
Length:1,679
Mass (Da):190,408
Last modified:September 23, 2008 - v1
Checksum:i241464C2D0B74DE4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH480819 Genomic DNA Translation: EDW53117.1
RefSeqiXP_002036958.1, XM_002036922.1

Genome annotation databases

EnsemblMetazoaiFBtr0195362; FBpp0193854; FBgn0167314
GeneIDi6612450
KEGGidse:Dsec_GM12377

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH480819 Genomic DNA Translation: EDW53117.1
RefSeqiXP_002036958.1, XM_002036922.1

3D structure databases

ProteinModelPortaliB4I0T6
SMRiB4I0T6
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0195362; FBpp0193854; FBgn0167314
GeneIDi6612450
KEGGidse:Dsec_GM12377

Organism-specific databases

FlyBaseiFBgn0167314 Dsec\GM12377

Phylogenomic databases

KOiK05694
OMAiIEDMHYG
OrthoDBiEOG091G00JF
PhylomeDBiB4I0T6

Family and domain databases

CDDicd00063 FN3, 8 hits
Gene3Di2.60.40.10, 8 hits
3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR000387 TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00041 fn3, 7 hits
PF00102 Y_phosphatase, 1 hit
PRINTSiPR00700 PRTYPHPHTASE
SMARTiView protein in SMART
SM00060 FN3, 10 hits
SM00194 PTPc, 1 hit
SM00404 PTPc_motif, 1 hit
SUPFAMiSSF49265 SSF49265, 5 hits
SSF52799 SSF52799, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 9 hits
PS00383 TYR_PHOSPHATASE_1, 1 hit
PS50056 TYR_PHOSPHATASE_2, 1 hit
PS50055 TYR_PHOSPHATASE_PTP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB4I0T6_DROSE
AccessioniPrimary (citable) accession number: B4I0T6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 10, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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