Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Serine/threonine-protein phosphatase Pgam5, mitochondrial

Gene

Pgam5

Organism
Drosophila persimilis (Fruit fly)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity (By similarity).By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase Pgam5, mitochondrialBy similarity (EC:3.1.3.16)
Alternative name(s):
Phosphoglycerate mutase family member 5 homologBy similarity
Gene namesi
Name:Pgam5By similarity
ORF Names:GL20215
OrganismiDrosophila persimilis (Fruit fly)
Taxonomic identifieri7234 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000008744 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0157810 Dper\GL20215

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 23HelicalSequence analysisAdd BLAST17

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003907071 – 289Serine/threonine-protein phosphatase Pgam5, mitochondrialAdd BLAST289

Interactioni

Subunit structurei

Interacts with Pk92B/ASK1.By similarity

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB4GXS1
SMRiB4GXS1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

KOiK15637
OMAiHLTNRIP
OrthoDBiEOG091G0DEJ
PhylomeDBiB4GXS1

Family and domain databases

CDDicd07067 HP_PGM_like, 1 hit
Gene3Di3.40.50.1240, 1 hit
InterProiView protein in InterPro
IPR013078 His_Pase_superF_clade-1
IPR029033 His_PPase_superfam
PfamiView protein in Pfam
PF00300 His_Phos_1, 2 hits
SMARTiView protein in SMART
SM00855 PGAM, 1 hit
SUPFAMiSSF53254 SSF53254, 1 hit

Sequencei

Sequence statusi: Complete.

B4GXS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKFTAFACG TGAGLLTFYL TKLNEPKAAV HNSWTRSEKP VDPCALWDHN
60 70 80 90 100
WDLRDPKSLV KPVKNDLSQE QNRYNTELEK VVPKHARHII LIRHGEYLDV
110 120 130 140 150
GDTDETHHLT ERGREQAKYT GKRLCELGIK WDKVIASTMV RAQETADIIL
160 170 180 190 200
NEIDYEKTKV KNCAFLREGA PIPPQPPVGH WKPEASQFFR DGARIEAAFR
210 220 230 240 250
RYFYRAYPDQ TKDSYTLLVG HGNVIRYFVC RALQFPPEAW LRISINHASI
260 270 280
TWLTISPSGN VSIKYLGDTG FMPVNHLTNR IPRAAKNVV
Length:289
Mass (Da):33,113
Last modified:September 23, 2008 - v1
Checksum:i4D179957B2D1BA3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH479196 Genomic DNA Translation: EDW27548.1
RefSeqiXP_002023400.1, XM_002023364.1

Genome annotation databases

EnsemblMetazoaiFBtr0185830; FBpp0184322; FBgn0157810
GeneIDi6598375
KEGGidpe:Dper_GL20215

Similar proteinsi

Entry informationi

Entry nameiPGAM5_DROPE
AccessioniPrimary (citable) accession number: B4GXS1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 19, 2010
Last sequence update: September 23, 2008
Last modified: March 28, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health