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Entry version 72 (16 Jan 2019)
Sequence version 1 (23 Sep 2008)
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Protein
Submitted name:

Serine/threonine-protein kinase MHK

Gene

100272250

Organism
Zea mays (Maize)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: InterPro
  • protein serine/threonine kinase activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinaseImported, Transferase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Serine/threonine-protein kinase MHKImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:100272250Imported
ORF Names:ZEAMMB73_Zm00001d034834Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiZea mays (Maize)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4577 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007305 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
B4FJ92

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
B4FJ92 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4577.GRMZM2G045241_P01

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 283Protein kinaseInterPro annotationAdd BLAST280

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0661 Eukaryota
ENOG410XPBB LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000233024

KEGG Orthology (KO)

More...
KOi
K08829

Identification of Orthologs from Complete Genome Data

More...
OMAi
IFEHMEC

Database of Orthologous Groups

More...
OrthoDBi
76933at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00069 Pkinase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00220 S_TKc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56112 SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

B4FJ92-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MERYKLIRKI GDGTCGNVFM ASNVETNEIV AVKKMKRKFC HWEECISLRE
60 70 80 90 100
VKALQKLFHP NIVKLKEVTM ENHELFFIFE HMECNLYDVI RERQVAFPER
110 120 130 140 150
DIRNFMVQIL QGLAYMHNNG YFHRDLKPEN LLVTNGIIKI ADFGLAREIS
160 170 180 190 200
SNPPYTDYVS TRWYRAPEVL LQSSVYTPAI DMWAVGAILA ELFTLSPLFP
210 220 230 240 250
GESETDQLYK ICTVLGTPDC TIWPEGMNLP RSCSFKFFQN PPRNLWELIP
260 270 280 290 300
NASSEAIDLI QQLCSWDPRR RPTAEQALQH PFFNVCNWVP RPVHDAYHTK
310 320 330 340 350
TNGPKAEPRL ELNLWDFSTE PDDCVLDLTL SLKPSFSGTD LGKHVPRRTE
360 370 380 390 400
EEILLYPGFE NTPVKSGFWP LVPSDRPVGD VPAIPSWQQA YMVDSQGAFS
410 420
GSPFLQSNLL ENRSLAPIRQ VNFF
Length:424
Mass (Da):48,777
Last modified:September 23, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE3EACDA32DDA9AB9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1D6LBT8A0A1D6LBT8_MAIZE
Serine/threonine-protein kinase MHK
100272250 ZEAMMB73_Zm00001d034834
319Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D6LBU0A0A1D6LBU0_MAIZE
Serine/threonine-protein kinase MHK
100272250 ZEAMMB73_Zm00001d034834
96Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D6LBU4A0A1D6LBU4_MAIZE
Serine/threonine-protein kinase MHK
100272250 ZEAMMB73_Zm00001d034834
96Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BT037180 mRNA Translation: ACF82185.1
BT037708 mRNA Translation: ACF82713.1
BT038347 mRNA Translation: ACF83352.1
EU967780 mRNA Translation: ACG39898.1
CM007647 Genomic DNA Translation: ONM11560.1
CM007647 Genomic DNA Translation: ONM11561.1
CM007647 Genomic DNA Translation: ONM11562.1
CM007647 Genomic DNA Translation: ONM11564.1
CM007647 Genomic DNA Translation: ONM11565.1
CM007647 Genomic DNA Translation: ONM11568.1

NCBI Reference Sequences

More...
RefSeqi
NP_001140217.1, NM_001146745.1
XP_008666097.1, XM_008667875.1
XP_008666104.1, XM_008667882.1
XP_008666111.1, XM_008667889.1
XP_008666116.1, XM_008667894.1

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Zm.8127

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
Zm00001d034834_T001; Zm00001d034834_P001; Zm00001d034834
Zm00001d034834_T002; Zm00001d034834_P002; Zm00001d034834
Zm00001d034834_T003; Zm00001d034834_P003; Zm00001d034834
Zm00001d034834_T005; Zm00001d034834_P005; Zm00001d034834
Zm00001d034834_T008; Zm00001d034834_P008; Zm00001d034834
Zm00001d034834_T009; Zm00001d034834_P009; Zm00001d034834

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100272250

Gramene; a comparative resource for plants

More...
Gramenei
Zm00001d034834_T001; Zm00001d034834_P001; Zm00001d034834
Zm00001d034834_T002; Zm00001d034834_P002; Zm00001d034834
Zm00001d034834_T003; Zm00001d034834_P003; Zm00001d034834
Zm00001d034834_T005; Zm00001d034834_P005; Zm00001d034834
Zm00001d034834_T008; Zm00001d034834_P008; Zm00001d034834
Zm00001d034834_T009; Zm00001d034834_P009; Zm00001d034834

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
zma:100272250

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT037180 mRNA Translation: ACF82185.1
BT037708 mRNA Translation: ACF82713.1
BT038347 mRNA Translation: ACF83352.1
EU967780 mRNA Translation: ACG39898.1
CM007647 Genomic DNA Translation: ONM11560.1
CM007647 Genomic DNA Translation: ONM11561.1
CM007647 Genomic DNA Translation: ONM11562.1
CM007647 Genomic DNA Translation: ONM11564.1
CM007647 Genomic DNA Translation: ONM11565.1
CM007647 Genomic DNA Translation: ONM11568.1
RefSeqiNP_001140217.1, NM_001146745.1
XP_008666097.1, XM_008667875.1
XP_008666104.1, XM_008667882.1
XP_008666111.1, XM_008667889.1
XP_008666116.1, XM_008667894.1
UniGeneiZm.8127

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

STRINGi4577.GRMZM2G045241_P01

Proteomic databases

PaxDbiB4FJ92

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiZm00001d034834_T001; Zm00001d034834_P001; Zm00001d034834
Zm00001d034834_T002; Zm00001d034834_P002; Zm00001d034834
Zm00001d034834_T003; Zm00001d034834_P003; Zm00001d034834
Zm00001d034834_T005; Zm00001d034834_P005; Zm00001d034834
Zm00001d034834_T008; Zm00001d034834_P008; Zm00001d034834
Zm00001d034834_T009; Zm00001d034834_P009; Zm00001d034834
GeneIDi100272250
GrameneiZm00001d034834_T001; Zm00001d034834_P001; Zm00001d034834
Zm00001d034834_T002; Zm00001d034834_P002; Zm00001d034834
Zm00001d034834_T003; Zm00001d034834_P003; Zm00001d034834
Zm00001d034834_T005; Zm00001d034834_P005; Zm00001d034834
Zm00001d034834_T008; Zm00001d034834_P008; Zm00001d034834
Zm00001d034834_T009; Zm00001d034834_P009; Zm00001d034834
KEGGizma:100272250

Phylogenomic databases

eggNOGiKOG0661 Eukaryota
ENOG410XPBB LUCA
HOGENOMiHOG000233024
KOiK08829
OMAiIFEHMEC
OrthoDBi76933at2759

Gene expression databases

ExpressionAtlasiB4FJ92 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB4FJ92_MAIZE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B4FJ92
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: January 16, 2019
This is version 72 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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