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Entry version 91 (16 Oct 2019)
Sequence version 1 (23 Sep 2008)
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Protein

Histone H3

Gene

103627323

Organism
Zea mays (Maize)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Histone H3UniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:103627323Imported
Synonyms:100192746Imported
ORF Names:ZEAMMB73_Zm00001d016908Imported, ZEAMMB73_Zm00001d029394Imported, ZEAMMB73_Zm00001d036036Imported, ZEAMMB73_Zm00001d045475Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiZea mays (Maize)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4577 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007305 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleosome coreUniRule annotationSAAS annotation, NucleusUniRule annotationSAAS annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4577.GRMZM2G171387_P01

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 132HistoneInterPro annotationAdd BLAST132

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 43DisorderedSequence analysisAdd BLAST43

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the histone H3 family.UniRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1745 Eukaryota
COG2036 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000155290

KEGG Orthology (KO)

More...
KOi
K11253

Identification of Orthologs from Complete Genome Data

More...
OMAi
CTMARTK

Database of Orthologous Groups

More...
OrthoDBi
1564596at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.20.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009072 Histone-fold
IPR007125 Histone_H2A/H2B/H3
IPR000164 Histone_H3/CENP-A

The PANTHER Classification System

More...
PANTHERi
PTHR11426 PTHR11426, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00125 Histone, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00622 HISTONEH3

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00428 H3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47113 SSF47113, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00322 HISTONE_H3_1, 1 hit
PS00959 HISTONE_H3_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

B4FCH2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARTKQTARK STGGKAPRKQ LATKAARKSA PTTGGVKKPH RYRPGTVALR
60 70 80 90 100
EIRKYQKSTE LLIRKLPFQR LVREIAQDFK TDLRFQSHAV LALQEAAEAY
110 120 130
LVGLFEDTNL CAIHAKRVTI MPKDIQLARR IRGERA
Length:136
Mass (Da):15,406
Last modified:September 23, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6D72383BF2E9EBE6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1D6K4W8A0A1D6K4W8_MAIZE
Histone H3
100192746 ZEAMMB73_Zm00001d029394
50Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D6HB41A0A1D6HB41_MAIZE
Histone H3
103627323 ZEAMMB73_Zm00001d016908
55Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BT034810 mRNA Translation: ACF79815.1
BT042286 mRNA Translation: ACF87291.1
BT043468 mRNA Translation: ACF88473.1
EU952417 mRNA Translation: ACG24535.1
EU952814 mRNA Translation: ACG24932.1
EU952884 mRNA Translation: ACG25002.1
EU953487 mRNA Translation: ACG25605.1
EU958923 mRNA Translation: ACG31041.1
EU958930 mRNA Translation: ACG31048.1
EU974018 mRNA Translation: ACG46136.1
BT087344 mRNA Translation: ACR37697.1
CM000781 Genomic DNA Translation: AQK71917.1
CM000781 Genomic DNA Translation: AQK71918.1
CM000781 Genomic DNA Translation: AQK71919.1
CM000781 Genomic DNA Translation: AQK71920.1
CM000781 Genomic DNA Translation: AQK71921.1
CM000781 Genomic DNA Translation: AQK71922.1
CM000782 Genomic DNA Translation: AQK80197.1
CM000785 Genomic DNA Translation: AQL02337.1
CM007647 Genomic DNA Translation: ONL98646.1
CM007647 Genomic DNA Translation: ONL98647.1
CM007647 Genomic DNA Translation: ONL98649.1

NCBI Reference Sequences

More...
RefSeqi
NP_001131417.1, NM_001137945.2
NP_001304168.1, NM_001317239.1
NP_001311109.1, NM_001324180.1
XP_008645853.1, XM_008647631.1
XP_008645854.1, XM_008647632.1
XP_008645855.1, XM_008647633.1
XP_008659340.1, XM_008661118.1

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
Zm00001d016908_T001; Zm00001d016908_P001; Zm00001d016908
Zm00001d016908_T002; Zm00001d016908_P002; Zm00001d016908
Zm00001d016908_T003; Zm00001d016908_P003; Zm00001d016908
Zm00001d016908_T004; Zm00001d016908_P004; Zm00001d016908
Zm00001d016908_T006; Zm00001d016908_P006; Zm00001d016908
Zm00001d016908_T007; Zm00001d016908_P007; Zm00001d016908
Zm00001d029394_T002; Zm00001d029394_P002; Zm00001d029394
Zm00001d029394_T003; Zm00001d029394_P003; Zm00001d029394
Zm00001d029394_T004; Zm00001d029394_P004; Zm00001d029394
Zm00001d036036_T001; Zm00001d036036_P001; Zm00001d036036
Zm00001d045475_T001; Zm00001d045475_P001; Zm00001d045475

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100192746
100194139
103627323
103638137

Gramene; a comparative resource for plants

More...
Gramenei
Zm00001d016908_T001; Zm00001d016908_P001; Zm00001d016908
Zm00001d016908_T002; Zm00001d016908_P002; Zm00001d016908
Zm00001d016908_T003; Zm00001d016908_P003; Zm00001d016908
Zm00001d016908_T004; Zm00001d016908_P004; Zm00001d016908
Zm00001d016908_T006; Zm00001d016908_P006; Zm00001d016908
Zm00001d016908_T007; Zm00001d016908_P007; Zm00001d016908
Zm00001d029394_T002; Zm00001d029394_P002; Zm00001d029394
Zm00001d029394_T003; Zm00001d029394_P003; Zm00001d029394
Zm00001d029394_T004; Zm00001d029394_P004; Zm00001d029394
Zm00001d036036_T001; Zm00001d036036_P001; Zm00001d036036
Zm00001d045475_T001; Zm00001d045475_P001; Zm00001d045475

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
zma:100192746
zma:100194139
zma:103627323
zma:103638137

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT034810 mRNA Translation: ACF79815.1
BT042286 mRNA Translation: ACF87291.1
BT043468 mRNA Translation: ACF88473.1
EU952417 mRNA Translation: ACG24535.1
EU952814 mRNA Translation: ACG24932.1
EU952884 mRNA Translation: ACG25002.1
EU953487 mRNA Translation: ACG25605.1
EU958923 mRNA Translation: ACG31041.1
EU958930 mRNA Translation: ACG31048.1
EU974018 mRNA Translation: ACG46136.1
BT087344 mRNA Translation: ACR37697.1
CM000781 Genomic DNA Translation: AQK71917.1
CM000781 Genomic DNA Translation: AQK71918.1
CM000781 Genomic DNA Translation: AQK71919.1
CM000781 Genomic DNA Translation: AQK71920.1
CM000781 Genomic DNA Translation: AQK71921.1
CM000781 Genomic DNA Translation: AQK71922.1
CM000782 Genomic DNA Translation: AQK80197.1
CM000785 Genomic DNA Translation: AQL02337.1
CM007647 Genomic DNA Translation: ONL98646.1
CM007647 Genomic DNA Translation: ONL98647.1
CM007647 Genomic DNA Translation: ONL98649.1
RefSeqiNP_001131417.1, NM_001137945.2
NP_001304168.1, NM_001317239.1
NP_001311109.1, NM_001324180.1
XP_008645853.1, XM_008647631.1
XP_008645854.1, XM_008647632.1
XP_008645855.1, XM_008647633.1
XP_008659340.1, XM_008661118.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi4577.GRMZM2G171387_P01

Genome annotation databases

EnsemblPlantsiZm00001d016908_T001; Zm00001d016908_P001; Zm00001d016908
Zm00001d016908_T002; Zm00001d016908_P002; Zm00001d016908
Zm00001d016908_T003; Zm00001d016908_P003; Zm00001d016908
Zm00001d016908_T004; Zm00001d016908_P004; Zm00001d016908
Zm00001d016908_T006; Zm00001d016908_P006; Zm00001d016908
Zm00001d016908_T007; Zm00001d016908_P007; Zm00001d016908
Zm00001d029394_T002; Zm00001d029394_P002; Zm00001d029394
Zm00001d029394_T003; Zm00001d029394_P003; Zm00001d029394
Zm00001d029394_T004; Zm00001d029394_P004; Zm00001d029394
Zm00001d036036_T001; Zm00001d036036_P001; Zm00001d036036
Zm00001d045475_T001; Zm00001d045475_P001; Zm00001d045475
GeneIDi100192746
100194139
103627323
103638137
GrameneiZm00001d016908_T001; Zm00001d016908_P001; Zm00001d016908
Zm00001d016908_T002; Zm00001d016908_P002; Zm00001d016908
Zm00001d016908_T003; Zm00001d016908_P003; Zm00001d016908
Zm00001d016908_T004; Zm00001d016908_P004; Zm00001d016908
Zm00001d016908_T006; Zm00001d016908_P006; Zm00001d016908
Zm00001d016908_T007; Zm00001d016908_P007; Zm00001d016908
Zm00001d029394_T002; Zm00001d029394_P002; Zm00001d029394
Zm00001d029394_T003; Zm00001d029394_P003; Zm00001d029394
Zm00001d029394_T004; Zm00001d029394_P004; Zm00001d029394
Zm00001d036036_T001; Zm00001d036036_P001; Zm00001d036036
Zm00001d045475_T001; Zm00001d045475_P001; Zm00001d045475
KEGGizma:100192746
zma:100194139
zma:103627323
zma:103638137

Phylogenomic databases

eggNOGiKOG1745 Eukaryota
COG2036 LUCA
HOGENOMiHOG000155290
KOiK11253
OMAiCTMARTK
OrthoDBi1564596at2759

Family and domain databases

Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR009072 Histone-fold
IPR007125 Histone_H2A/H2B/H3
IPR000164 Histone_H3/CENP-A
PANTHERiPTHR11426 PTHR11426, 1 hit
PfamiView protein in Pfam
PF00125 Histone, 1 hit
PRINTSiPR00622 HISTONEH3
SMARTiView protein in SMART
SM00428 H3, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit
PROSITEiView protein in PROSITE
PS00322 HISTONE_H3_1, 1 hit
PS00959 HISTONE_H3_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB4FCH2_MAIZE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B4FCH2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 16, 2019
This is version 91 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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