UniProtKB - B4E3W2 (B4E3W2_HUMAN)
Protein
Submitted name:
Fanconi anemia group C protein
Gene
FANCC
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Fanconi anemia group C proteinImportedSubmitted name: cDNA FLJ61092, highly similar to Fanconi anemia group C proteinImported |
Gene namesi | Name:FANCCImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:3584, FANCC |
Subcellular locationi
Nucleus
- Fanconi anaemia nuclear complex Source: InterPro
Expressioni
Gene expression databases
ExpressionAtlasi | B4E3W2, baseline and differential |
Genevisiblei | B4E3W2, HS |
Family & Domainsi
Phylogenomic databases
GeneTreei | ENSGT00390000016390 |
OrthoDBi | 1546359at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR000686, FANCC |
PANTHERi | PTHR16798, PTHR16798, 1 hit |
Pfami | View protein in Pfam PF02106, Fanconi_C, 1 hit |
PRINTSi | PR00494, FANCONICGENE |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All
B4E3W2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAQDSVDLSC DYQFWMQKLS VWDQASTLET QQDTCLHVAQ FQEFLRKMYE
60 70 80 90 100
ALKEMDSNTV IERFPTIGQL LAKACWNPFI LAYDESQKIL IWCLCCLINK
110
EPQNSGQSKL NSWIQ
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ00597 | FANCC_HUMAN | Fanconi anemia group C protein | FANCC FAC, FACC | 558 | Annotation score: | ||
A0A087WW44 | A0A087WW44_HUMAN | Fanconi anemia group C protein | FANCC | 492 | Annotation score: | ||
A0A0S2Z3N5 | A0A0S2Z3N5_HUMAN | Fanconi anemia complementation grou... | FANCC | 119 | Annotation score: | ||
B1ALR7 | B1ALR7_HUMAN | Fanconi anemia group C protein | FANCC | 150 | Annotation score: | ||
A0A3B3IS26 | A0A3B3IS26_HUMAN | Fanconi anemia group C protein | FANCC | 135 | Annotation score: | ||
A0A3B3IS92 | A0A3B3IS92_HUMAN | Fanconi anemia group C protein | FANCC | 131 | Annotation score: | ||
A0A3B3IU87 | A0A3B3IU87_HUMAN | Fanconi anemia group C protein | FANCC | 153 | Annotation score: | ||
A0A3B3ITN9 | A0A3B3ITN9_HUMAN | Fanconi anemia group C protein | FANCC | 58 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL157384 Genomic DNA No translation available. AL161729 Genomic DNA No translation available. AL354893 Genomic DNA No translation available. AL446023 Genomic DNA No translation available. AK304887 mRNA Translation: BAG65624.1 |
RefSeqi | NP_001230673.1, NM_001243744.1 |
Genome annotation databases
Ensembli | ENST00000474949; ENSP00000497729; ENSG00000158169 ENST00000649519; ENSP00000497630; ENSG00000158169 |
GeneIDi | 2176 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL157384 Genomic DNA No translation available. AL161729 Genomic DNA No translation available. AL354893 Genomic DNA No translation available. AL446023 Genomic DNA No translation available. AK304887 mRNA Translation: BAG65624.1 |
RefSeqi | NP_001230673.1, NM_001243744.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
DNASUi | 2176 |
Genome annotation databases
Ensembli | ENST00000474949; ENSP00000497729; ENSG00000158169 ENST00000649519; ENSP00000497630; ENSG00000158169 |
GeneIDi | 2176 |
Organism-specific databases
CTDi | 2176 |
HGNCi | HGNC:3584, FANCC |
OpenTargetsi | ENSG00000158169 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000016390 |
OrthoDBi | 1546359at2759 |
Miscellaneous databases
BioGRID-ORCSi | 2176, 39 hits in 848 CRISPR screens |
ChiTaRSi | FANCC, human |
GenomeRNAii | 2176 |
Gene expression databases
ExpressionAtlasi | B4E3W2, baseline and differential |
Genevisiblei | B4E3W2, HS |
Family and domain databases
InterProi | View protein in InterPro IPR000686, FANCC |
PANTHERi | PTHR16798, PTHR16798, 1 hit |
Pfami | View protein in Pfam PF02106, Fanconi_C, 1 hit |
PRINTSi | PR00494, FANCONICGENE |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B4E3W2_HUMAN | |
Accessioni | B4E3W2Primary (citable) accession number: B4E3W2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 23, 2008 |
Last sequence update: | September 23, 2008 | |
Last modified: | December 2, 2020 | |
This is version 63 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |