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Protein
Submitted name:

Heterogeneous nuclear ribonucleoprotein R, isoform CRA_a

Gene

HNRNPR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRibonucleoproteinImported, RNA-bindingPROSITE-ProRule annotation, Viral nucleoproteinImported

Names & Taxonomyi

Protein namesi
Submitted name:
Heterogeneous nuclear ribonucleoprotein R, isoform CRA_aImported
Submitted name:
cDNA FLJ54544, highly similar to Heterogeneous nuclear ribonucleoprotein RImported
Gene namesi
Name:HNRNPRImported
Synonyms:HNRPRImported
ORF Names:hCG_38907Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000125944.18
HGNCiHGNC:5047 HNRNPR

Subcellular locationi

    Keywords - Cellular componenti

    Virion

    Pathology & Biotechi

    Organism-specific databases

    OpenTargetsiENSG00000125944

    PTM / Processingi

    Proteomic databases

    MaxQBiB4DT28
    PRIDEiB4DT28

    Expressioni

    Gene expression databases

    BgeeiENSG00000125944

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    Domaini26 – 105RRMInterPro annotationAdd BLAST80
    Domaini107 – 189RRMInterPro annotationAdd BLAST83
    Domaini202 – 272RRMInterPro annotationAdd BLAST71

    Phylogenomic databases

    GeneTreeiENSGT00550000074366
    HOVERGENiHBG051917

    Family and domain databases

    CDDicd12488 RRM2_hnRNPR, 1 hit
    Gene3Di3.30.70.330, 3 hits
    InterProiView protein in InterPro
    IPR006535 HnRNP_R/Q_splicing_fac
    IPR034411 hnRNPR_RRM2
    IPR012677 Nucleotide-bd_a/b_plait_sf
    IPR035979 RBD_domain_sf
    IPR000504 RRM_dom
    PfamiView protein in Pfam
    PF00076 RRM_1, 3 hits
    SMARTiView protein in SMART
    SM00360 RRM, 3 hits
    SUPFAMiSSF54928 SSF54928, 3 hits
    TIGRFAMsiTIGR01648 hnRNP-R-Q, 1 hit
    PROSITEiView protein in PROSITE
    PS50102 RRM, 3 hits

    Sequencei

    Sequence statusi: Complete.

    B4DT28-1 [UniParc]FASTAAdd to basket

    « Hide

            10         20         30         40         50
    MKTYRQREKQ GSKVQESTKG PDEAKIKVFV GKIPRDLYED ELVPLFEKAG
    60 70 80 90 100
    PIWDLRLMMD PLSGQNRGYA FITFCGKEAA QEAVKLCDSY EIRPGKHLGV
    110 120 130 140 150
    CISVANNRLF VGSIPKNKTK ENILEEFSKV TEGLVDVILY HQPDDKKKNR
    160 170 180 190 200
    GFCFLEYEDH KSAAQARRRL MSGKVKVWGN VVTVEWADPV EEPDPEVMAK
    210 220 230 240 250
    VKVLFVRNLA TTVTEEILEK SFSEFGKLER VKKLKDYAFV HFEDRGAAVK
    260 270 280 290 300
    AMDEMNGKEI EGEEIEIVLA KPPDKKRKER QAARQASRST AYEDYYYHPP
    310 320 330 340 350
    PRMPPPIRGR GRGGGRGGYG YPPDYYGYED YYDDYYGYDY HDYRGGYEDP
    360 370 380 390 400
    YYGYDDGYAV RGRGGGRGGR GAPPPPRGRG APPPRGRAGY SQRGAPLGPP
    410 420 430 440 450
    RGSRGGRGGP AQQQRGRGSR GSRGNRGGNV GGKRKADGYN QPDSKRRQTN
    460 470 480 490
    NQQNWGSQPI AQQPLQQGGD YSGNYGYNND NQEFYQDTYG QQWK
    Length:494
    Mass (Da):55,718
    Last modified:September 23, 2008 - v1
    Checksum:i45858B5A0A499397
    GO

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AL109936 Genomic DNA No translation available.
    AK300029 mRNA Translation: BAG61840.1
    CH471134 Genomic DNA Translation: EAW95040.1
    RefSeqiNP_001284551.1, NM_001297622.1
    UniGeneiHs.373763

    Genome annotation databases

    EnsembliENST00000606561; ENSP00000475760; ENSG00000125944
    ENST00000635199; ENSP00000489386; ENSG00000282958
    GeneIDi10236
    UCSCiuc009vql.4 human

    Similar proteinsi

    Entry informationi

    Entry nameiB4DT28_HUMAN
    AccessioniPrimary (citable) accession number: B4DT28
    Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: July 18, 2018
    This is version 78 of the entry and version 1 of the sequence. See complete history.
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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