UniProtKB - B4DRC2 (B4DRC2_HUMAN)
Protein
Submitted name:
Sex comb on midleg-like protein 2
Gene
SCML2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Sex comb on midleg-like protein 2ImportedSubmitted name: cDNA FLJ60333, highly similar to Sex comb on midleg-like protein 2Imported |
Gene namesi | Name:SCML2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:10581, SCML2 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 13 – 60 | RBRInterPro annotationAdd BLAST | 48 | |
Domaini | 92 – 201 | SLEDInterPro annotationAdd BLAST | 110 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 56 | DisorderedSequence analysisAdd BLAST | 56 | |
Regioni | 202 – 287 | DisorderedSequence analysisAdd BLAST | 86 | |
Regioni | 307 – 345 | DisorderedSequence analysisAdd BLAST | 39 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 21 | PolarSequence analysisAdd BLAST | 21 | |
Compositional biasi | 210 – 231 | PolyampholyteSequence analysisAdd BLAST | 22 | |
Compositional biasi | 307 – 325 | PolarSequence analysisAdd BLAST | 19 |
Phylogenomic databases
GeneTreei | ENSGT00940000159407 |
Family and domain databases
Gene3Di | 1.20.1380.20, 1 hit |
InterProi | View protein in InterPro IPR033763, SCML2_RBR IPR021987, SLED IPR038348, SLED_sf |
Pfami | View protein in Pfam PF17208, RBR, 1 hit PF12140, SLED, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
B4DRC2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQSPQKTTLI LPTQQVRRSS RIKPPGPTAV PKRSSSVKNI TPRKKGPNSG
60 70 80 90 100
KKEKPLPVIC STSAASLKSL TRDRGMLYKD VASGPCKIVM STVCVYVNKH
110 120 130 140 150
GNFGPHLDPK RIQQLPDHFG PGPVNVVLRR IVQACVDCAL ETKTVFGYLK
160 170 180 190 200
PDNRGGEVIT ASFDGETHSI QLPPVNSASF ALRFLENFCH SLQCDNLLSS
210 220 230 240 250
QPFSSSRGHT HSSAEHDKNQ SAKEDVTERQ STKRSPQQTV PYVVPLSPKL
260 270 280 290 300
PKTKEYASEG EPLFAGGSAI PKEENLSEDS KSSSLNSGNY LNPACRNPMY
310 320 330 340
IHTSVSQDFS RSVPGTTSSP LVGDISPKSS PHEVKFQMQR KSEGN
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UQR0 | SCML2_HUMAN | Sex comb on midleg-like protein 2 | SCML2 | 700 | Annotation score: | ||
H0Y6S1 | H0Y6S1_HUMAN | Sex comb on midleg-like protein 2 | SCML2 | 124 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL031007 Genomic DNA No translation available. AL096763 Genomic DNA No translation available. KF459011 Genomic DNA No translation available. Z93023 Genomic DNA No translation available. AK299190 mRNA Translation: BAG61234.1 |
Genome annotation databases
Ensembli | ENST00000665583; ENSP00000499630; ENSG00000102098 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL031007 Genomic DNA No translation available. AL096763 Genomic DNA No translation available. KF459011 Genomic DNA No translation available. Z93023 Genomic DNA No translation available. AK299190 mRNA Translation: BAG61234.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | B4DRC2 |
PRIDEi | B4DRC2 |
ProteomicsDBi | 4939 |
Protocols and materials databases
Antibodypediai | 475, 168 antibodies |
Genome annotation databases
Ensembli | ENST00000665583; ENSP00000499630; ENSG00000102098 |
Organism-specific databases
HGNCi | HGNC:10581, SCML2 |
OpenTargetsi | ENSG00000102098 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000159407 |
Gene expression databases
ExpressionAtlasi | B4DRC2, baseline and differential |
Family and domain databases
Gene3Di | 1.20.1380.20, 1 hit |
InterProi | View protein in InterPro IPR033763, SCML2_RBR IPR021987, SLED IPR038348, SLED_sf |
Pfami | View protein in Pfam PF17208, RBR, 1 hit PF12140, SLED, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B4DRC2_HUMAN | |
Accessioni | B4DRC2Primary (citable) accession number: B4DRC2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 23, 2008 |
Last sequence update: | September 23, 2008 | |
Last modified: | October 7, 2020 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |