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Protein
Submitted name:

cDNA FLJ51975, moderately similar to 14-3-3 protein epsilon (14-3-3E)

Gene

YWHAE

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ51975, moderately similar to 14-3-3 protein epsilon (14-3-3E)Imported
Gene namesi
Name:YWHAEImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000108953.16
HGNCiHGNC:12851 YWHAE

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000108953

PTM / Processingi

Proteomic databases

MaxQBiB4DJF2
PeptideAtlasiB4DJF2
PRIDEiB4DJF2

Expressioni

Gene expression databases

BgeeiENSG00000108953 Expressed in 237 organ(s), highest expression level in female gonad
ExpressionAtlasiB4DJF2 baseline and differential

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 9414_3_3InterPro annotationAdd BLAST91

Sequence similaritiesi

Belongs to the 14-3-3 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0841 Eukaryota
COG5040 LUCA
GeneTreeiENSGT00760000119116
HOVERGENiHBG050423

Family and domain databases

Gene3Di1.20.190.20, 1 hit
InterProiView protein in InterPro
IPR000308 14-3-3
IPR023409 14-3-3_CS
IPR036815 14-3-3_dom_sf
IPR023410 14-3-3_domain
PANTHERiPTHR18860 PTHR18860, 1 hit
PfamiView protein in Pfam
PF00244 14-3-3, 1 hit
SMARTiView protein in SMART
SM00101 14_3_3, 1 hit
SUPFAMiSSF48445 SSF48445, 1 hit
PROSITEiView protein in PROSITE
PS00796 1433_1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

B4DJF2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDDREDLVYQ AKLAEQAERY DEMVESMKKV AGMDVELTVE ERNLLSVAYK
60 70 80 90
NVIGARRASW RIISSIEQKE ENKGGEDKLK MIREYRQMVG KSSF
Length:94
Mass (Da):10,949
Last modified:September 23, 2008 - v1
Checksum:i7CC825310D03C7C3
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P622581433E_HUMAN
14-3-3 protein epsilon
YWHAE
255Annotation score:
K7EIT4K7EIT4_HUMAN
14-3-3 protein epsilon
YWHAE
109Annotation score:
K7EM20K7EM20_HUMAN
14-3-3 protein epsilon
YWHAE
115Annotation score:
I3L3T1I3L3T1_HUMAN
14-3-3 protein epsilon
YWHAE
107Annotation score:
I3L0W5I3L0W5_HUMAN
14-3-3 protein epsilon
YWHAE
38Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC032044 Genomic DNA No translation available.
AK296050 mRNA Translation: BAG58814.1
UniGeneiHs.513851

Genome annotation databases

EnsembliENST00000573196; ENSP00000461766; ENSG00000108953
ENST00000630606; ENSP00000486352; ENSG00000274474
UCSCiuc059zen.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC032044 Genomic DNA No translation available.
AK296050 mRNA Translation: BAG58814.1
UniGeneiHs.513851

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB4DJF2
PeptideAtlasiB4DJF2
PRIDEiB4DJF2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000573196; ENSP00000461766; ENSG00000108953
ENST00000630606; ENSP00000486352; ENSG00000274474
UCSCiuc059zen.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000108953.16
HGNCiHGNC:12851 YWHAE
OpenTargetsiENSG00000108953
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0841 Eukaryota
COG5040 LUCA
GeneTreeiENSGT00760000119116
HOVERGENiHBG050423

Miscellaneous databases

ChiTaRSiYWHAE human

Gene expression databases

BgeeiENSG00000108953 Expressed in 237 organ(s), highest expression level in female gonad
ExpressionAtlasiB4DJF2 baseline and differential

Family and domain databases

Gene3Di1.20.190.20, 1 hit
InterProiView protein in InterPro
IPR000308 14-3-3
IPR023409 14-3-3_CS
IPR036815 14-3-3_dom_sf
IPR023410 14-3-3_domain
PANTHERiPTHR18860 PTHR18860, 1 hit
PfamiView protein in Pfam
PF00244 14-3-3, 1 hit
SMARTiView protein in SMART
SM00101 14_3_3, 1 hit
SUPFAMiSSF48445 SSF48445, 1 hit
PROSITEiView protein in PROSITE
PS00796 1433_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB4DJF2_HUMAN
AccessioniPrimary (citable) accession number: B4DJF2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: September 12, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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