UniProtKB - B4DIH5 (B4DIH5_HUMAN)
Protein
COP9 signalosome complex subunit 2
Gene
COPS2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: COP9 signalosome complex subunit 2ARBA annotation |
Gene namesi | Name:COPS2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000166200.14 |
HGNCi | HGNC:30747, COPS2 |
Subcellular locationi
Nucleus
- COP9 signalosome Source: InterPro
Other locations
- cytoplasm Source: UniProtKB-SubCell
Expressioni
Gene expression databases
Bgeei | ENSG00000166200, Expressed in calcaneal tendon and 247 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 190 – 352 | PCIInterPro annotationAdd BLAST | 163 |
Sequence similaritiesi
Belongs to the CSN2 family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00530000063301 |
HOGENOMi | CLU_028981_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR037750, COPS2 IPR000717, PCI_dom IPR011990, TPR-like_helical_dom_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR10678:SF3, PTHR10678:SF3, 1 hit |
Pfami | View protein in Pfam PF01399, PCI, 1 hit |
SMARTi | View protein in SMART SM00088, PINT, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF48452, SSF48452, 1 hit |
PROSITEi | View protein in PROSITE PS50250, PCI, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
B4DIH5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDMEDDFMC DDEEDYDLTN FPEMMNRYKQ LLTYIRSAVT RNYSEKSINS
60 70 80 90 100
ILDYISTSKQ MDLLQEFYET TLEALKDAKN DRLWFKTNTK LGKLYLEREE
110 120 130 140 150
YGKLQKILRQ LHQSCQTDDG EDDLKKGTQL LEIYALEIQM YTAQKNNKKL
160 170 180 190 200
KALYEQSLHI KSAIPHPLIM GVIRECGGKM HLREGEFEKA HTDFFEAFKN
210 220 230 240 250
YDESGSPRRT TCLKYLVLAN MLMKSGINPF DSQEAKPYKN DPEILAMTNL
260 270 280 290 300
VSAYQNNDIT EFEKILKTNH SNIMDDPFIR EHIEELLRNI RTQVLIKLIK
310 320 330 340 350
PYTRIHIPFI SKELNIDVAD VESLLVQCIL DNTIHGRIDQ VNQLLELDHQ
360 370
KRGGARYTAL DKWTNQLNSL NQAVVSKLA
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP61201 | CSN2_HUMAN | COP9 signalosome complex subunit 2 | COPS2 CSN2, TRIP15 | 443 | Annotation score: | ||
H0YM03 | H0YM03_HUMAN | COP9 signalosome complex subunit 2 | COPS2 | 183 | Annotation score: | ||
H0YKU5 | H0YKU5_HUMAN | COP9 signalosome complex subunit 2 | COPS2 | 263 | Annotation score: | ||
H0YMC2 | H0YMC2_HUMAN | COP9 signalosome complex subunit 2 | COPS2 | 55 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC013452 Genomic DNA No translation available. AK295598 mRNA Translation: BAG58487.1 |
Genome annotation databases
Ensembli | ENST00000542928; ENSP00000443664; ENSG00000166200 |
UCSCi | uc010ufa.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC013452 Genomic DNA No translation available. AK295598 mRNA Translation: BAG58487.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | B4DIH5 |
PRIDEi | B4DIH5 |
ProteomicsDBi | 4306 |
Protocols and materials databases
Antibodypediai | 12106, 396 antibodies |
Genome annotation databases
Ensembli | ENST00000542928; ENSP00000443664; ENSG00000166200 |
UCSCi | uc010ufa.3, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000166200.14 |
HGNCi | HGNC:30747, COPS2 |
OpenTargetsi | ENSG00000166200 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00530000063301 |
HOGENOMi | CLU_028981_0_0_1 |
Miscellaneous databases
ChiTaRSi | COPS2, human |
Gene expression databases
Bgeei | ENSG00000166200, Expressed in calcaneal tendon and 247 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR037750, COPS2 IPR000717, PCI_dom IPR011990, TPR-like_helical_dom_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR10678:SF3, PTHR10678:SF3, 1 hit |
Pfami | View protein in Pfam PF01399, PCI, 1 hit |
SMARTi | View protein in SMART SM00088, PINT, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF48452, SSF48452, 1 hit |
PROSITEi | View protein in PROSITE PS50250, PCI, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B4DIH5_HUMAN | |
Accessioni | B4DIH5Primary (citable) accession number: B4DIH5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 23, 2008 |
Last sequence update: | September 23, 2008 | |
Last modified: | October 7, 2020 | |
This is version 100 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |