UniProtKB - B4DGG2 (B4DGG2_HUMAN)
Protein
Submitted name:
cDNA FLJ56070, highly similar to Sorting nexin-13
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- phosphatidylinositol binding Source: InterPro
GO - Biological processi
- positive regulation of GTPase activity Source: InterPro
- protein transport Source: UniProtKB-KW
Keywordsi
Biological process | Protein transportARBA annotation, Transport |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA FLJ56070, highly similar to Sorting nexin-13Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 35 – 59 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 65 – 98 | HelicalSequence analysisAdd BLAST | 34 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 145 – 332 | PXAInterPro annotationAdd BLAST | 188 | |
Domaini | 421 – 544 | RGSInterPro annotationAdd BLAST | 124 | |
Domaini | 607 – 728 | PXInterPro annotationAdd BLAST | 122 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 25 | DisorderedSequence analysisAdd BLAST | 25 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 341 – 361 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 831 – 851 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the sorting nexin family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisFamily and domain databases
CDDi | cd06873, PX_SNX13, 1 hit cd08719, RGS_SNX13, 1 hit |
Gene3Di | 3.30.1520.10, 1 hit |
InterProi | View protein in InterPro IPR003114, Phox_assoc IPR001683, PX_dom IPR036871, PX_dom_sf IPR016137, RGS IPR036305, RGS_sf IPR037437, SNX13_PX IPR037896, SNX13_RGS IPR013937, Sorting_nexin_C |
Pfami | View protein in Pfam PF08628, Nexin_C, 1 hit PF00787, PX, 1 hit PF02194, PXA, 1 hit PF00615, RGS, 1 hit |
SMARTi | View protein in SMART SM00312, PX, 1 hit SM00313, PXA, 1 hit SM00315, RGS, 1 hit |
SUPFAMi | SSF48097, SSF48097, 1 hit SSF64268, SSF64268, 1 hit |
PROSITEi | View protein in PROSITE PS50195, PX, 1 hit PS51207, PXA, 1 hit PS50132, RGS, 1 hit |
i Sequence
Sequence statusi: Complete.
B4DGG2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAARPSRATG PRGGQRSRVK PPPGRRLKEQ LPPLAAARAV FAAATAVIML
60 70 80 90 100
TEASLSIWGW GSLGIVLFLI TFGPFVIFYL TFYILCYVGG GLVVTLLFGK
110 120 130 140 150
TNSEKYLEQC EHSFLPPTSP GVPKCLEEMK REARIIKIDR RLTGANIIDE
160 170 180 190 200
PLQQVIQFSL RDYVQYWYYT LSDDESFLLE IRQTLQNALI QFATRSKEID
210 220 230 240 250
WQPYFTTRIV DDFGTHLRVF RKAQQKITEK DDQVKGTAED LVDTFFEVEV
260 270 280 290 300
EMEKEVCRDL VCTSPKDEEG FLRDLCEVLL YLLLPPGDFQ NKIMRYFVRE
310 320 330 340 350
ILARGILLPL INQLSDPDYI NQYVIWMIRD SNCNYEAFMN IIKLSDNIGE
360 370 380 390 400
LEAVRDKAAE ELQYLRSLDT AGDDINTIKN QINSLLFVKK VCDSRIQRLQ
410 420 430 440 450
SGKEINTVKL AANFGKLCTV PLDSILVDNV ALQFFMDYMQ QTGGQAHLFF
460 470 480 490 500
WMTVEGYRVT AQQQLEVLLS RQRDGKHQTN QTKGLLRAAA VGIYEQYLSE
510 520 530 540 550
KASPRVTVDD YLVAKLADTL NHEDPTPEIF DDIQRKVYEL MLRDERFYPS
560 570 580 590 600
FRQNALYVRM LAELDMLKDP SFRGSDDGDG ESFNGSPTGS INLSLDDLSN
610 620 630 640 650
VSSDDSVQLH AYISDTGVCN DHGKTYALYA ITVHRRNLNS EEMWKTYRRY
660 670 680 690 700
SDFHDFHMRI TEQFESLSSI LKLPGKKTFN NMDRDFLEKR KKDLNAYLQL
710 720 730 740 750
LLAPEMMKAS PALAHYVYDF LENKAYSKGK GDFARKMDTF VNPLRNSMRN
760 770 780 790 800
VSNAVKSLPD SLAEGMTKMS DNMGKMSERL GQDIKQSFFK VPPLIPKTDS
810 820 830 840 850
DPEHRRVSAQ LDDNVDDNIP LRVMLLLMDE VFDLKERNQW LRRNIKNLLQ
860 870 880 890 900
QLIRATYGDT INRKIVDHVD WMTSPEQVAD SVKRFRDAFW PNGILAEAVP
910 920 930 940 950
CRDKSIRMRT RVAGKTKLLA IMPDELKHII GAETTRKGIL RVFEMFQHNQ
960 970 980 990 1000
LNRRMVYVFL EGFLETLFPQ YKFRELFNKL HSRSKQMQKY KQKLQTTQAP
SLQKR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK294582 mRNA Translation: BAG57773.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK294582 mRNA Translation: BAG57773.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | B4DGG2 |
Family and domain databases
CDDi | cd06873, PX_SNX13, 1 hit cd08719, RGS_SNX13, 1 hit |
Gene3Di | 3.30.1520.10, 1 hit |
InterProi | View protein in InterPro IPR003114, Phox_assoc IPR001683, PX_dom IPR036871, PX_dom_sf IPR016137, RGS IPR036305, RGS_sf IPR037437, SNX13_PX IPR037896, SNX13_RGS IPR013937, Sorting_nexin_C |
Pfami | View protein in Pfam PF08628, Nexin_C, 1 hit PF00787, PX, 1 hit PF02194, PXA, 1 hit PF00615, RGS, 1 hit |
SMARTi | View protein in SMART SM00312, PX, 1 hit SM00313, PXA, 1 hit SM00315, RGS, 1 hit |
SUPFAMi | SSF48097, SSF48097, 1 hit SSF64268, SSF64268, 1 hit |
PROSITEi | View protein in PROSITE PS50195, PX, 1 hit PS51207, PXA, 1 hit PS50132, RGS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B4DGG2_HUMAN | |
Accessioni | B4DGG2Primary (citable) accession number: B4DGG2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 23, 2008 |
Last sequence update: | September 23, 2008 | |
Last modified: | December 2, 2020 | |
This is version 61 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |