UniProtKB - B4DFJ1 (B4DFJ1_HUMAN)
Protein
Submitted name:
TERF1-interacting nuclear factor 2
Gene
TINF2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: TERF1-interacting nuclear factor 2ImportedSubmitted name: cDNA FLJ53728, highly similar to TERF1-interacting nuclear factor 2Imported |
Gene namesi | Name:TINF2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:11824, TINF2 |
Subcellular locationi
Nucleus
- nuclear body Source: HPA
- nucleoplasm Source: HPA
- shelterin complex Source: InterPro
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 20 – 64 | TINF2_NInterPro annotationAdd BLAST | 45 | |
Domaini | 64 – 134 | TINF2_NInterPro annotationAdd BLAST | 71 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 194 – 222 | DisorderedSequence analysisAdd BLAST | 29 |
Phylogenomic databases
GeneTreei | ENSGT00400000022326 |
Family and domain databases
CDDi | cd11657, TIN2_N, 1 hit |
InterProi | View protein in InterPro IPR039098, TINF2 IPR029400, TINF2_N |
PANTHERi | PTHR15512, PTHR15512, 2 hits |
Pfami | View protein in Pfam PF14973, TINF2_N, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
B4DFJ1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATPLVAGPA ALRFAAAASW QVVRGRCVEH FPRVLEFLRS LRAVAPGLVR
60 70 80 90 100
YRHHERLCMG LKAKTKQDLR KILEAQETFY QQVKQLSEAP VDLASKLQEL
110 120 130 140 150
EQEYGEPFLA AMEKLLFEYL CQLEKALPTP QAQQLQDVLS WMQPGVSITS
160 170 180 190 200
SLAWRQYGVD MGWLLPECSV TDSVNLAEPM EQNPPQQQRL ALHNPLPKAK
210 220 230 240 250
PGTHLPQGPS SRTHPEPLAG RHFNLAPLGR RRVQSQWAST RGGHKERPTV
260 270 280 290 300
MLFPFRNLGS PTQVISKPES KEEHAIYTAD LAMGTRAAST GKSKSPCQTL
310 320 330 340 350
GGRALKENPV DLPATEQKEN CLDCYMDPLR LSLLPPRARK PVCPPSLCSS
360 370 380 390 400
VITIGDLVLD SDEEENGQGE GKESLENYQK TKFDTLIPTL CEYLPPSGHG
410
AIPVSSCDCR DSSRPL
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9BSI4 | TINF2_HUMAN | TERF1-interacting nuclear factor 2 | TINF2 TIN2 | 451 | Annotation score: | ||
H0YKA6 | H0YKA6_HUMAN | TERF1-interacting nuclear factor 2 | TINF2 | 146 | Annotation score: | ||
H0YL96 | H0YL96_HUMAN | TERF1-interacting nuclear factor 2 | TINF2 | 85 | Annotation score: | ||
H0YLC9 | H0YLC9_HUMAN | TERF1-interacting nuclear factor 2 | TINF2 | 290 | Annotation score: | ||
H0YL20 | H0YL20_HUMAN | TERF1 (TRF1)-interacting nuclear fa... | TINF2 hCG_38254 | 140 | Annotation score: | ||
H0YMN3 | H0YMN3_HUMAN | TERF1-interacting nuclear factor 2 | TINF2 | 71 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL096870 Genomic DNA No translation available. AK294119 mRNA Translation: BAG57452.1 |
RefSeqi | XP_005267586.1, XM_005267529.3 |
Genome annotation databases
Ensembli | ENST00000646753; ENSP00000494065; ENSG00000092330 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL096870 Genomic DNA No translation available. AK294119 mRNA Translation: BAG57452.1 |
RefSeqi | XP_005267586.1, XM_005267529.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | B4DFJ1 |
PRIDEi | B4DFJ1 |
ProteomicsDBi | 4045 |
Protocols and materials databases
Antibodypediai | 22798, 223 antibodies |
Genome annotation databases
Ensembli | ENST00000646753; ENSP00000494065; ENSG00000092330 |
Organism-specific databases
HGNCi | HGNC:11824, TINF2 |
OpenTargetsi | ENSG00000092330 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00400000022326 |
Miscellaneous databases
BioGRID-ORCSi | 26277, 672 hits in 884 CRISPR screens |
ChiTaRSi | TINF2, human |
GenomeRNAii | 26277 |
Gene expression databases
ExpressionAtlasi | B4DFJ1, baseline and differential |
Family and domain databases
CDDi | cd11657, TIN2_N, 1 hit |
InterProi | View protein in InterPro IPR039098, TINF2 IPR029400, TINF2_N |
PANTHERi | PTHR15512, PTHR15512, 2 hits |
Pfami | View protein in Pfam PF14973, TINF2_N, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B4DFJ1_HUMAN | |
Accessioni | B4DFJ1Primary (citable) accession number: B4DFJ1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 23, 2008 |
Last sequence update: | September 23, 2008 | |
Last modified: | February 10, 2021 | |
This is version 67 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |